Thioxanthone is a heterocyclic compound that is a sulfur analog of xanthone. Thioxanthone can be prepared by the reaction of diphenyl sulfide with phosgene in the presence of catalytic aluminium chloride. This synthesis can be seen as a special case of the Friedel-Crafts acylation. The reduction product is thioxanthene. Thioxanthone dissolves in concentrated sulfuric acid to give a yellow colored liquid with intense green fluorescence. A mixture of the thioxanthone derivatives of 2- and 4-isopropylthioxanthone (ITX) is used in the printing industry. Pharmaceutical drugs that are derivatives of thioxanthone include hycanthone and lucanthone.
Formula
C13H8OS
Molecular Weight
212.267
Exact Mass
212.03
LogP
3.4147
PSA
45.31
Synonyms
9-Oxothioxanthene,Thioxanthone
Thioxanthen-9-one
9H-Thioxanthen-9-one
Thioxanthone
9-Oxothioxanthene,Thioxanthen-9-one
9-Oxothioxanthene
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Properties
Appearance & Physical State
slightly yellow crystalline powder
Density
1.309g/cm3
Boiling Point
371-373ºC (715 mmHg)
Melting Point
211-216ºC
Flash Point
371-373°C/715mm
Refractive Index
1.692
Water Solubility
practically insoluble
Stability
Stable. Incompatible with strong oxidizing agents.
Storage Condition
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
