Leu-enkephalin is an endogenous opioid peptide neurotransmitter with the amino acid sequence Tyr-Gly-Gly-Phe-Leu that is found naturally in the brains of many animals, including humans. It is one of the two forms of enkephalin; the other is met-enkephalin. The tyrosine residue at position 1 is thought to be analogous to the 3-hydroxyl group on morphine. Leu-enkephalin has agonistic actions at both the μ- and δ-opioid receptors, with significantly greater preference for the latter. It has little to no effect on the κ-opioid receptor.
LEU-ENKEPHALIN
H-TyrGlyGlyPheLeu-OH
L-TYR-GLY-GLY-PHE-LEU
SGS 518 oxalate
LEUCINE-ENKEPHALIN
Leu-Enkelphalin
L-leucine enkephalin
enkephalin,leucine
ENKEPHALIN L
TYR-GLY-GLY-PHE-LEU
YGGFL
H2N-Tyr-Gly-Gly-Phe-Leu-COOH
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