58822-25-6 structure, C28H37N5O7

[LEU5]-ENKEPHALIN

CAS No.

58822-25-6

Formula:

C28H37N5O7

Basic Info

Leu-enkephalin is an endogenous opioid peptide neurotransmitter with the amino acid sequence Tyr-Gly-Gly-Phe-Leu that is found naturally in the brains of many animals, including humans. It is one of the two forms of enkephalin; the other is met-enkephalin. The tyrosine residue at position 1 is thought to be analogous to the 3-hydroxyl group on morphine. Leu-enkephalin has agonistic actions at both the μ- and δ-opioid receptors, with significantly greater preference for the latter. It has little to no effect on the κ-opioid receptor.

Formula
C28H37N5O7
Molecular Weight
555.623
Exact Mass
555.269
LogP
2.1013
PSA
199.95
Synonyms

LEU-ENKEPHALIN

H-TyrGlyGlyPheLeu-OH

L-TYR-GLY-GLY-PHE-LEU

SGS 518 oxalate

LEUCINE-ENKEPHALIN

Leu-Enkelphalin

L-leucine enkephalin

enkephalin,leucine

ENKEPHALIN L

TYR-GLY-GLY-PHE-LEU

YGGFL

H2N-Tyr-Gly-Gly-Phe-Leu-COOH

expand collapse

Properties

Appearance & Physical State
White lyophilized powder
Density
1.274 g/cm3
Boiling Point
998.8ºC at 760 mmHg
Flash Point
557.8ºC
Refractive Index
1.586
Storage Condition
-20ºC

Safety Info

Safety Statements
S22-S24/25
WGK Germany
3

Synthesis Route

1.Synthesis Route
2.Synthesis Route
3.Synthesis Route

Related Compound Information