DADLE|63631-40-3 - MOLBASE Encyclopedia

: DADLE

CAS No.
63631-40-3

Formula:
C29H39N5O7

DADLE ([D-Ala2, D-Leu5]-Enkephalin) is a synthetic opioid peptide with analgesic properties. Although it is often considered a selective delta opioid receptor agonist, it also binds to the μ1 subtype of mu opioid receptors.
Treatment with DADLE results in transient depression of mean arterial blood pressure and heart rate.
Its peptide sequence is Tyr-D-Ala-Gly-Phe-D-Leu.

YAGFL

2-D-Alanine-5-D-leucine-enkephalin

<D-Ala2,D-Leu5>Leu-enkephalin

Enkephalin,Leucine-2-Alanine

TYR-D-ALA-GLY-PHE-D-LEU

TYR-D-ALA-GLY-PHE-D-LEU ACOH H2O

H-Tyr-D-Ala-Gly-Phe-D-Leu-OH

BW-180

D-Leu5>nekephalin

expand collapse

1.Synthesis Route

240820-24-0

63631-40-3

91-64-5

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Related Compound Information

DADLE
FMRF AMIDE
2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanamide
(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoic acid
2-[[2-[[2-[(2-formamido-4-methylsulfanylbutanoyl)amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoic acid
2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
acetic acid,(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanamide
DAGO ACETATE SALT
FMRF AMIDE
H-D-PHE-MET-ARG-PHE-NH2

DADLE

63631-40-3

C29H39N5O7

Basic Info

Properties

Synthesis Route

1.Synthesis Route

Related Compound Information

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