1.Identification

1.1 GHS Product identifier

1.2 Other means of identification

1.3 Recommended use of the chemical and restrictions on use

1.4 Supplier's details

1.5 Emergency phone number

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 4

Acute toxicity - Dermal, Category 4

Skin irritation, Category 2

Skin sensitization, Category 1

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H312 Harmful in contact with skin H315 Causes skin irritation H317 May cause an allergic skin reaction H410 Very toxic to aquatic life with long lasting effects
Precautionary statement(s)
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment.
Response	P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P312 Call a POISON CENTER/doctor/…if you feel unwell. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P332+P313 If skin irritation occurs: Get medical advice/attention. P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest. Refer for medical attention.

In case of skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap.

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

Inhalation or ingestion causes nausea, headache, weight loss, convulsions, possible kidney and liver damage. Contact with eyes causes irritation. (USCG, 1999)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Observation. Persons exposed to high levels of organochlorine pesticides by any route should be observed for sensory disturbances, incoordination, speech slurring, mental aberrations, and involuntary motor activity that would warn of imminent convulsions. /Solid organochlorine insecticides/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.)

5.2 Specific hazards arising from the chemical

Special Hazards of Combustion Products: Irritating hydrogen chloride fumes may form in fire. Behavior in Fire: Xylene solvent vapors may travel to source of ignition and flash back. (USCG, 1999)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: complete protective clothing including self-contained breathing apparatus.

6.3 Methods and materials for containment and cleaning up

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a POTW is acceptable only after review by the governing authority. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must meet Hazardous Material Criteria for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Separated from acids. Keep in a well-ventilated room.Store above 40 deg F, away from feed, foodstuffs, or any body of water.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

Liquid solvent may be flammable.DICOFOL is an organochlorine bridged diphenyl. Halogenated aliphatic compounds are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Halogenated aliphatics are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides. DICOFOL hydrolyzes in alkali. It is slightly corrosive to metals. Contact with steel at elevated temperatures causes formation of toxic gases. .

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Contact with steel at elevated temp causes formation of toxic chlorine & hydrogen chloride gases.

10.6 Hazardous decomposition products

Dangerous: when heated to decomposition ... they evolve highly toxic /hydrogen/ chloride fumes. /chlorides/

11.Toxicological information

Acute toxicity

• Oral: LD50 Rat oral 684-809 mg/kg
• Inhalation: LC50 Rat inhalation >5 mg/L over 4 hrs
• Dermal: LD50 Rabbit percutaneous 2100 mg/kg

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Cancer Classification: Group C Possible Human Carcinogen

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

• Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill, weight 1 g); Conditions: freshwater, static, 18°C, pH 7.1, hardness 44 mg/L CaCO3; Concentration: 1050 ug/L for 24 hr (95% confidence interval: 889-1241 ug/L) /100% purity technical material
• Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea, age 2-26 hr, adult); Conditions: freshwater, static; 80 ug/L for 24 hr (95% confidence interval: 71-90 ug/L); Effect: intoxication, immobilization /formulated product
• Toxicity to algae: no data available
• Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: Dicofol, present at 100 mg/L, reached 0% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1). Dicofol degraded with a half-life of 43 days in a silt loam soil(2). The major metabolites were 1,1-(p-chlorophenyl)-2,2-dichloroethanol, p,p'-DCBP, and 3-hydroxy-4,4'-dichlorobenzophenone(2). Volatile residues were 21-22% of the applied, and unextractable residues were 10-15% of the applied after 12 months(2). In a different study, the aerobic biodegradation half-life of dicofol in soil is expected to range from 259 to 348 days based upon a 300 day open bottle experiment with mixed soil (conducted indoors) and a 300 day open bottle experiment with surface soil (conducted outdoors), respectively(3).

12.3 Bioaccumulative potential

BCFs of 8200 and 6100 were measured in carp (Coprinus carpio) exposed for a 60 day incubation period at concns of 1.0 and 0.1 ug/L of dicofol, respectively(1). The BCF of dicofol was measured as 15,000, 18,900, 9,500 and 14,500 in fathead minnow at dicofol concns of 12.38, 1.15, 14.95 and 1.33 ppb, respectively(2). Dicofol residues accumulated in bluegill sunfish with BCFs of 6,600, 17,000, and 10,000 in fillet, viscera, and whole fish, respectively, during 28 days of exposure(3). The estimated elimination half-life was 33 days(3). BCFs in fish were reported as 8050-13,500 based on whole body weight(4). According to a classification scheme(5), these BCF values suggest the potential for bioconcentration in aquatic organisms is very high. In crop areas, the highest mean concns of dicofol measured in the biotic matrices were 1.4 ppm for small mammals (FL), 3.9 ppm for terrestrial invertebrates (CA), and 3.8 ppm for reptiles/amphibians (FL)(3). In non-crop areas, highest mean concns were 0.3 ppm for small mammals (NY), 0.76 ppm for terrestrial invertebrates (FL), 0.38 ppm for reptiles/amphibians (FL), 0.9 ppm for birds (FL), and 0.26 ppm for fish (FL)(3).

12.4 Mobility in soil

The Koc for dicofol is 8,383 in sand, 8,073 in sandy loam, 5,868 in silty loam, and 5,917 in clay loam(1). Other reported Koc values for dicofol are 7,207 in sand (0.2% organic matter, pH 6.5), 6,945 in sandy loam (1.6% organic matter, pH 5.8), 5,017 in silty loam (2.4% organic matter, pH 7.1), and 5,086 in clay loam (2.8% organic matter, pH 7.0)(2). Dicofol shows moderate to low mobility in batch equilibrium and column leaching studies, with little potential to leach to groundwater(3). In batch equilibrium studies, mobility of dicofol was moderate in sand (Koc of 5,868), and clay loam (Koc of 5,917) soil slurries(3). According to a classification scheme(4), these Koc values suggest that dicofol is expected to be immobile in soil.

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

14.2 UN Proper Shipping Name

14.3 Transport hazard class(es)

14.4 Packing group, if applicable

14.5 Environmental hazards

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

16.Other information

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.