33125-97-2 structure, C14H16N2O2

etomidate

CAS No.

33125-97-2

Formula:

C14H16N2O2

Basic Info

Etomidate (USAN, INN, BAN) (marketed as Amidate) is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation for short procedures such as reduction of dislocated joints, tracheal intubation, and cardioversion. It was discovered at Janssen Pharmaceutica in 1964 and was introduced as an intravenous agent in 1972 in Europe and in 1983 in the United States.

Formula
C14H16N2O2
Molecular Weight
244.289
Exact Mass
244.121
LogP
2.6691
PSA
44.12
Synonyms

Amidate,R16659

R-1665

Amidate R16659

PROPISCIN

HYPNOMIDATE

(R)-Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate

RADENARCON

Etomidate

D-ETOMIDATE

(R)-(+)-1-(1-Phenylethyl)-1H-imidazole-5-carboxylic Acid Ethyl Ester

AMIDATE

Ethyl (R)-(+)-1-(1-Phenylethyl)-1H-imidazole-5-carboxylate

expand collapse

Properties

Appearance & Physical State
White powder.
Density
1.11g/cm3
Boiling Point
391.5ºC at 760mmHg
Melting Point
72-74ºC
Flash Point
190.6ºC
Refractive Index
1.561
Stability
Stable at normal temperatures and pressures.
Storage Condition
2-8ºC

Safety Info

Safety Statements
S36
Risk Statements
R22
HS Code
2933990090
Caution Statement
P273
Hazard Codes
Xn
Hazard Declaration

H302; H400
Caution Statement

P273

Synthesis Route

1.Synthesis Route

1445-91-6

23785-21-9

33125-97-2
2.Synthesis Route

97849-55-3

56649-48-0

33125-97-2

Precursor

56649-48-0 spectrum, Etomidate Acid

56649-48-0
1445-91-6 spectrum, (S)-1-phenylethanol

1445-91-6
23785-21-9 spectrum, ethyl 1H-imidazole-5-carboxylate

23785-21-9
97849-55-3 spectrum, [1-11C]ethyl iodide

97849-55-3

Downstream Product

56649-48-0
Home > Encyclopedia > Miscellaneous > Chemical Reagents > Aromatic Compounds > etomidate

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