486460-32-6 structure, C16H15F6N5O

sitagliptin

CAS No.

486460-32-6

Formula:

C16H15F6N5O

Basic Info

Sitagliptin (INN; previously identified as MK-0431 and marketed as the phosphate salt under the trade name Januvia) is an oral antihyperglycemic (antidiabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class. It was developed, and is marketed, by Merck & Co. This enzyme-inhibiting drug is used either alone or in combination with other oral antihyperglycemic agents (such as metformin or a thiazolidinedione) for treatment of diabetes mellitus type 2.

Formula
C16H15F6N5O
Molecular Weight
407.314
Exact Mass
407.118
LogP
2.6547
PSA
77.04
Synonyms

Janumet

Sitagliptin

Unii-qfp0p1dv7z

expand collapse

Properties

Appearance & Physical State
yellow grease
Density
1.614g/cm3
Boiling Point
529.905ºC at 760 mmHg
Flash Point
274.277ºC
Refractive Index
1.59

Synthesis Route

Downstream Product

Related Compound Information