72-55-9 structure, C14H8Cl4

DDE

CAS No.

72-55-9

Formula:

C14H8Cl4

Basic Info

4,4'-DDE is a metabolite of DDT, a synthetic organochlorine insecticide that functions by opening sodium ion channels in the insects’ neurons, causing them to fire spontaneously which in turn leads to death. 4,4'-DDE has shown to have endocrine disrupting effects on gonadotropin hormones in pituitary gonadotrope cells.

Formula
C14H8Cl4
Molecular Weight
318.025
Exact Mass
315.938
LogP
6.1879
PSA
0
Synonyms

Benzene, 1,1‘-(dichloroethenylidene)bis[4-chloro-

2,2-Bis(4-chlorophenyl)-1,1-dichloroethylene

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Properties

Appearance & Physical State
white crystalline powder
Melting Point
87-90ºC
Flash Point
11ºC
Stability
Stable, but light-sensitive. Incompatible with strong bases, strong oxidizing agents.
Storage Condition
APPROX 4ºC

Safety Info

RTECS
KV9450000
Safety Statements
S26; S36/37/39
WGK Germany
3
Risk Statements
R22; R33
HS Code
2903999090
RIDADR
UN 3077 9/PG 3
Hazard Codes

MSDS

SDS 1.0
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SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name DDE

1.2 Other means of identification

Product number -
Other names 2,2-Bis(4-chlorophenyl)-1,1-dichloroethylene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. DDT was extensively used in the past for the control of malaria, typhus, and other insect-transmitted diseases. It was banned for use in the United States in 1972, except in the case of a public health emergency. DDE is a breakdown product of DDT and has no uses.
Uses advised against no data available

1.4 Supplier's details

Company MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road,
Xuhui District, Shanghai, China
Telephone +86(21)64956998
Fax +86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-400-6021-666
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Not classified.

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Warning

Hazard statement(s)

H302 Harmful if swallowed

H311 Toxic in contact with skin

H315 Causes skin irritation

H331 Toxic if inhaled

H332 Harmful if inhaled

H400 Very toxic to aquatic life

Precautionary statement(s)
Prevention

none

Response

none

Storage

none

Disposal

none

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
DDE DDE 72-55-9 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

SYMPTOMS: Symptoms of exposure to this compound may include liver and kidney damage. Based on data for a similar compound, symptoms may also include vomiting, headache, fatigue, malaise, numbness and partial paralysis of the extremities, moderate ataxia, exaggeration of part of the reflexes, mild convulsions, loss of porprioception and vibratory sensation of the extremities, hyperactive knee-jerk reflexes, excitement, confusion and increased respiration. It may also cause nausea and diarrhea. Other symptoms may include tremors of the head and neck muscles, cardiac and respiratory failure and even death. It may also cause paresthesias of the tongue, lips and face, irritability and dizziness. It may cause tonic and clonic convulsions. Other symptoms include apprehension and hyperesthesia of the mouth and face. It may also cause "yellow vision". ACUTE/CHRONIC HAZARDS: This compound is harmful if ingested, inhaled or absorbed through the skin. It may cause irritation. There is clear evidence that this compound is an animal carcinogen. When heated to decomposition it emits very toxic fumes of carbon monoxide and carbon dioxide. It may also emit toxic fumes of hydrogen chloride gas.

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Observation. Persons exposed to high levels of organochlorine pesticides by any route should be observed for sensory disturbances, incoordination, speech slurring, mental aberrations, and involuntary motor activity that would warn of imminent convulsions. /Solid organochlorine insecticides/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher.

5.2 Specific hazards arising from the chemical

Flash point data for this chemical are not available. It is probably combustible.

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a POTW is acceptable only after review by the governing authority. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must meet Hazardous Material Criteria for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practicable to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. /Chemical Carcinogens/

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state white crystalline powder
Colour White, crystalline solid
Odour no data available
Melting point/ freezing point 4°C(lit.)
Boiling point or initial boiling point and boiling range 124°C/16mmHg(lit.)
Flammability no data available
Lower and upper explosion limit / flammability limit no data available
Flash point 107°C(lit.)
Auto-ignition temperature no data available
Decomposition temperature no data available
pH no data available
Kinematic viscosity no data available
Solubility less than 0.1 mg/mL at 22.22°C
Partition coefficient n-octanol/water (log value) log Kow = 6.51
Vapour pressure 6.0X10-6 mm Hg at 25°C
Density and/or relative density no data available
Relative vapour density no data available
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

P,P'-DDE is sensitive to exposure to light. This compound is incompatible with strong oxidizing agents and strong bases. Oxidation is catalyzed by UV radiation.

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

When heated to decomposition it emits very toxic fumes of /chlorides/.

11.Toxicological information

Acute toxicity

  • Oral: LD50 Rat oral 880 mg/kg
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Cancer Classification: Group B2 Probable Human Carcinogen

Reproductive toxicity

No information is available on the reproductive or developmental effects of DDT or DDE in humans via inhalation exposure. No studies are available on the developmental effects in humans after oral exposure to DDT or DDE. However, DDT and DDE have been found in human blood, placental tissue, and umbilical cord blood. Epidemiologic studies did not find an association between DDT maternal blood levels and miscarriages or premature rupture of fetal membranes in humans. Oral animal studies have reported reproductive effects, such as reduced fertility, adverse effects on spermatogenesis, and decreased testicular and ovarian weights from DDT exposure. Developmental effects, such as embryotoxicity and fetotoxicity, but not teratogenicity (birth defects) have also been observed in oral animal studies. DDT has been shown to elicit estrogenic activity in rats after oral exposure .

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: LC50; Species: Oncorhynchus mykiss (Rainbow trout, weight 0.8 g); Conditions: freshwater, static, 12°C, pH 7.1, hardness 44 mg/L CaCO3; Concentration: >87 ug/L for 24 hr /99% purity, technical material
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: DDE was not degraded in static screening tests using settled domestic wastewater inoculum with yeast extract, with 3 additional subcultures added every 7 days(1). No degradation of DDE exposed to ocean sediments in seawater under aerobic conditions were observed after 12 months(2). No degradation of DDE observed after 8 weeks of exposure of DDE in lab tests to raw water from a stream which received domestic and industrial wastes and farm runoff(3). Half-life of DDE exposed to river sediments was 1,100 days(4). BOD after 30 days of <1.0 ug O2/mL for DDE exposed to soil inoculum indicated only slight biodegradation(5).

12.3 Bioaccumulative potential

BCF values of DDE have been reported in the following aquatic organisms: rainbow trout, 81,000(2); fathead minnow, 51,000(3); fish (no species reported, static microcosm study), 27,500(4); Gambusia affinis, 217 (3 days exposure)(1); trout, 1.8X10+5, bluegill sunfish, 1.1X10+5(6). According to a classification scheme(7), these BCF data suggest bioconcentration in aquatic organisms is very high(SRC). BCF values of 28,600 have been reported in zooplankton(5).

12.4 Mobility in soil

The Koc value of p,p'-DDE in soil from Taichung, Taiwan was measured as 26,300(1) and 75,860(2) in soil column batch experiments. The avg log Koc value of DDE in lake sediment was 4.58(3). According to a classification scheme(4), these Koc values suggest that DDE is expected to be immobile in soil(SRC).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN3077 IMDG: UN3077 IATA: UN3077

14.2 UN Proper Shipping Name

ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.

14.3 Transport hazard class(es)

ADR/RID: 9 IMDG: 9 IATA: 9

14.4 Packing group, if applicable

ADR/RID: III IMDG: III IATA: III

14.5 Environmental hazards

ADR/RID: no IMDG: no IATA: no

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
DDE DDE 72-55-9 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Not Listed.
China Catalog of Hazardous chemicals 2015 Not Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Not Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 12, 2017
Revision Date Aug 12, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
MSDS
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Name: 2 2-Bis-(4-chlorophenyl)-1 1-dichloroethylene 99% Material Safety Data Sheet
Synonym: p,p'-DDE ; ethylene,1,1-dichloro-2,2-bis-(p-chlorophenyl)- ; DDT dehydrochloride ; DDE; 1-1'-(Dichloroethenylidene)bis(4-chlorobenzene
CAS: 72-55-9
Section 1 - Chemical Product   MSDS Name:2 2-Bis-(4-chlorophenyl)-1 1-dichloroethylene 99% Material Safety Data Sheet
Synonym:p,p'-DDE ; ethylene,1,1-dichloro-2,2-bis-(p-chlorophenyl)- ; DDT dehydrochloride ; DDE; 1-1'-(Dichloroethenylidene)bis(4-chlorobenzene

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
72-55-9 2,2-Bis-(4-chlorophenyl)-1,1-dichloroe 99 200-784-6
Hazard Symbols: XN
Risk Phrases: 22 33

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Harmful if swallowed. Danger of cumulative effects.Cancer suspect agent.Possible risks of irreversible effects.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed. Ingestion of large amounts may cause liver and/or kidney damage.
Inhalation:
May cause respiratory tract irritation.
Chronic:
May cause cancer according to animal studies. Adverse reproductive effects have been reported in animals. Laboratory experiments have resulted in mutagenic effects.

Section 4 - FIRST AID MEASURES
  Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire.
Extinguishing Media:
For large fires, use water spray, fog or regular foam. For small fires, use dry chemical, carbon dioxide, water spray or regular foam.
Cool containers with flooding quantities of water until well after fire is out.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Do not ingest or inhale. Use with adequate ventilation.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 72-55-9: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Crystals
Color: white
Odor: None reported.
pH: Not available.
Vapor Pressure: 6.5106 mm Hg @ 20 C
Viscosity: Not available.
Boiling Point: 336 deg C
Freezing/Melting Point: 88.00 - 90.00 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: 0.010 ppm
Specific Gravity/Density:
Molecular Formula: C14H8Cl4
Molecular Weight: 318.02

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents - strong bases.
Hazardous Decomposition Products:
Hydrogen chloride, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 72-55-9: KV9450000 LD50/LC50:
CAS# 72-55-9: Oral, mouse: LD50 = 700 mg/kg; Oral, rat: LD50 = 880 mg/kg.
Carcinogenicity:
2,2-Bis-(4-chlorophenyl)-1,1-dichloroethylene - California: carcinogen, initial date 1/1/89 Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
  Ecotoxicity:
Estimated BCF value = 8,300 based on water solubility. Estimated Koc value = 8,300. There was no movement of DDE reported in soil column mobility experiments.

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
USA RQ: CAS# 72-55-9: 1 lb final RQ; 0.454 kg final RQ

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
R 33 Danger of cumulative effects.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 72-55-9: 3
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 72-55-9 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 72-55-9 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

Spectrum

NMR Spectrum 1H NMR : Predict
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Analysis Methods

Kovats' RI, non-polar column, isothermal
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Column Shape
Packed
Active Phase(℃)
Apiezon L
Retention index
2180.
Temperature Control
215.
Method
isothermal
Comments
Chromosorb W; Column length: 1.8 m
Reference
Heinzen, V.E.F.Yunes, R.A.Relationship between gas chromatographic retention indices and molecular connectivity indices of chlorinated pesticides and structurally related compoundsJ. Chromatogr.1992, 598, 2, 243-250.
Kovats' RI, non-polar column, isothermal
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Column Shape
Packed
Active Phase(℃)
Apiezon L
Retention index
2132.
Temperature Control
215.
Method
isothermal
Comments
Chromosorb W; Column length: 1.8 m
Reference
Heinzen, V.E.F.Yunes, R.A.Relationship between gas chromatographic retention indices and molecular connectivity indices of chlorinated pesticides and structurally related compoundsJ. Chromatogr.1992, 598, 2, 243-250.
Kovats' RI, non-polar column, isothermal
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Column Shape
Packed
Active Phase(℃)
OV-1
Retention index
2136.
Temperature Control
200.
Method
isothermal
Comments
Column length: 2. m
Reference
Dubsky, H.Hána, K.Komárková, M.Rittich, B.Stanoveni residui chlórovanych pesticidu plynovou chromatografiiVet. Med. (Prague)1979, 24, 3, 493-498.
Kovats' RI, non-polar column, custom temperature program
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Column Shape
Packed
Active Phase(℃)
SE-30
Retention index
2130.
Temperature Control
Method
custom temperature program
Comments
He, Chromosorb G HP (80-100 mesh); Column length: 1.5 m; Program: not specified
Reference
Ramsey, J.D.Lee, T.D.Osselton, M.D.Moffat, A.C.Gas-liquid chromatographic retention indices of 296 non-drug substances on SE-30 or OV-1 likely to be encountered in toxicological analysesJ. Chromatogr.1980, 184, 2, 185-206.
Van Den Dool and Kratz RI, non-polar column, temperature ramp
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Column Shape
Capillary
Active Phase(℃)
OV-1
Retention index
2113.
Temperature Control
Method
temperature ramp
Comments
25. m/0.32 mm/0.10 μm, 160. C @ 1. min, 1. K/min; T<sub>end</sub>: 240. C
Reference
de Paoli, M.Taccheo-Barbina, M.Bontempelli, G.Gas chromatographic system for the identification of halogenated pesticides by retention indices using n-alkanes as standardsJ. Chromatogr.1991, 547, 355-365.

Toxicity

ACUTE TOXICITY DATA
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Type of Test
LD50 - Lethal dose, 50 percent kill
Exposure Route
Oral
Species Observed
Rodent - rat
Dose/Duration
880 mg/kg
Toxic Effects
Details of toxic effects not reported other than lethal dose value--
Reference
Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 14,515,1969
ACUTE TOXICITY DATA
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Type of Test
LD50 - Lethal dose, 50 percent kill
Exposure Route
Oral
Species Observed
Rodent - mouse
Dose/Duration
700 mg/kg
Toxic Effects
Details of toxic effects not reported other than lethal dose value--
Reference
Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 88,400,1946
ACUTE TOXICITY DATA
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Type of Test
LD50 - Lethal dose, 50 percent kill
Exposure Route
Oral
Species Observed
Rodent - hamster
Dose/Duration
>5 gm/kg
Toxic Effects
Details of toxic effects not reported other than lethal dose value--
Reference
Laboratory Animal Science. (American Assoc. for Laboratory Animal Science, 210 N. Hammes Ave., Suite 205, Joliet, IL 60435) V.21- 1971- Volume(issue)/page/year: 26,274,1976

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