1.Identification

1.1 GHS Product identifier

1.2 Other means of identification

1.3 Recommended use of the chemical and restrictions on use

1.4 Supplier's details

1.5 Emergency phone number

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 4

Acute toxicity - Inhalation, Category 4

Carcinogenicity, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H332 Harmful if inhaled H351 Suspected of causing cancer H400 Very toxic to aquatic life
Precautionary statement(s)
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P280 Wear protective gloves/protective clothing/eye protection/face protection. P273 Avoid release to the environment.
Response	P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell. P330 Rinse mouth. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P312 Call a POISON CENTER/doctor/…if you feel unwell. P308+P313 IF exposed or concerned: Get medical advice/ attention. P391 Collect spillage.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest. Refer for medical attention.

In case of skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap.

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rinse mouth. Give a slurry of activated charcoal in water to drink. Give one or two glasses of water to drink. Refer for medical attention . See Notes.

4.2 Most important symptoms/effects, acute and delayed

Excerpt from ERG Guide 151 [Substances - Toxic (Non-combustible)]: Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Carbamates and related compounds/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

/Wear/ self-contained breathing apparatus with a full facepiece operated in pressure-demand or other positive pressure mode /when fighting fire/.

5.2 Specific hazards arising from the chemical

Excerpt from ERG Guide 151 [Substances - Toxic (Non-combustible)]: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways. (ERG, 2016)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Remove all ignition sources. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

6.3 Methods and materials for containment and cleaning up

Store in original containers only. If the contents are leaking or material is spilled, follow these steps while wearing protective equipment. 1. Collect and place in suitable containers for disposal. 2. Wash area with soap and water to remove remaining pesticides. 3. Follow washing with clear water rinse. 4. Do not allow runoff to enter sewer or contaminate water supplies.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Separated from oxidants and food and feedstuffs. Well closed. Keep in a well-ventilated room.PESTICIDE STORAGE: Storage should be under lock and key and secure from access by unauthorized persons and children. Storage should be in a cool, dry area away from any heat or ignition source. Do not allow storage in a damp or humid area. Do not stack over 2 pallets high. Move bags carefully so as not to tear or puncture. Do not move from one area to another unless they are securely sealed to prevent dust from escaping. Keep container tightly sealed when not in use. Keep away from any puncture source. Avoid storage near water supplies, food, feed and fertilizer to avoid contamination. Avoid contamination with acids and alkalies. Store in original containers only.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 5 mg/cu m.

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

STABLE TO HEAT, LIGHT, ACIDS; HYDROLYZED IN ALKALIES

10.3 Possibility of hazardous reactions

... FLAMMABILITY POINT OF 193 DEG C.CARBARYL is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates. This compound is unstable in an alkaline media. . This compound is incompatible with the following: Strong oxidizers, strongly alkaline pesticides (NIOSH, 2016).

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

... Incompatible with alkaline materials such as Bordeaux mixture, lime, and lime sulfur.

10.6 Hazardous decomposition products

When heated to decomposition it emits toxic fumes of /nitrogen oxides/.

11.Toxicological information

Acute toxicity

• Oral: LD50 Rat oral 230 mg/kg
• Inhalation: no data available
• Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Cancer Classification: Likely to be Carcinogenic to Humans

Reproductive toxicity

No information is available on the reproductive or developmental effects of carbaryl in humans. Two studies produced teratogenic effects in dogs fed carbaryl, but dogs were judged inappropriate for human health risk assessment because of differences in metabolism. Other studies demonstrating teratogenic effects also caused maternal toxicity. Reduced fertility and litter size and increased mortality in offspring have been observed in rats exposed to carbaryl in their diet over three generations.

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

• Toxicity to fish: LC50; Species: /Salmo salar/ (Atlantic salmon, weight 0.4 g); Conditions: static bioassay; Concentration: 4500 ug/L for 96 hr (95% confidence limit: 3820-5310 ug/L) /Technical material, 99.5%
• Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea, juvenile about 4 days); Conditions: freshwater, static, 20°C, pH 8.0, alkalinity 250 mg/L CaCO3; Concentration: 21 ug/L for 24 hr (95% confidence interval: 17-25 ug/L); Effect: intoxication, immobilization /formulated product
• Toxicity to algae: no data available
• Toxicity to microorganisms: no data available

12.2 Persistence and degradability

THE PERSISTENCE OF 14C-CARBONYL-LABELED CARBARYL AT CONCN OF 2 & 200 PPM IN 5 DIFFERENT JAPANESE RICE PADDY SOILS WAS STUDIED. EVOLUTION OF CARBON DIOXIDE WAS NOT RAPID & VARIED BETWEEN 2% & 40% OVER 32 DAY TEST PERIOD. HYDROLYSIS OF CARBONYL LINKAGE WAS THE DOMINANT METABOLIC PATHWAY. AN ISOLATED SOIL MICROORGANISM RAPIDLY DEGRADED NAPHTHOL & PRODUCED A NUMBER OF UNIDENTIFIED AROMATIC COMPOUNDS.

12.3 Bioaccumulative potential

Carbaryl had a measured BCF value of 34, 30 and 9 in golden orfe(1), golden ide(2), and topmouth gudeon, respectively(3). An avg BCF of 9 was determined based on data compilations of freshwater fish at steady state with carbaryl in solution and by the kinetic method (ratio between first-order uptake and elimination rate constants)(4). According to a classification scheme(5), these BCF values suggest the potential for bioconcentration in aquatic organisms is low(SRC).

12.4 Mobility in soil

Carbaryl was estimated to leach <20 cm/yr assuming an annual rainfall of 150 cm; a loam soil and a temperature of 25°C were assumed(1). Soil-sorption coefficient (Koc) values of 370 and 390 were determined using a soil slurry method and reverse phase HPLC, respectively(2). In another study, carbaryl had a Koc value of 230(3). Freundlich k values are 0.017 and 0.046 in kaolinite and bentonite clays, respectively(4). In Ca-bentionite, alluvial and highly calcareous soils, the Freundlich adsorption isotherm showed a non-linear pattern and the adsorption was found to be temperature dependent, the adsorption being higher at lower temperature(5). In a study of the degradation and sorption from urban creek sediments from southern California, the sorption coefficient of carbaryl increased with time, indicating that in sediment carbaryl may become less available over time because of increased sorption(6). After 1 day of incubation, the estimated Koc was 310 to 420 for carbaryl. The measured Kd values of carbaryl in sediment after 1, 2, 6, and 28 days were 2.1, 2.4, 5.6, and 47.7 mL/g, respectively(6). A Koc of 230 mL/g has been reported for carbaryl(7). Carbaryl was reported to have a mean Koc value of 288 in the 1993 UK database(8). According to a classification scheme(2), these Koc values suggest that carbaryl is expected to have moderate mobility in soil.

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

14.2 UN Proper Shipping Name

14.3 Transport hazard class(es)

14.4 Packing group, if applicable

14.5 Environmental hazards

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

16.Other information

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.