1.Identification
1.1 GHS Product identifier
| Product name | diazinon |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | Antlak |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | For industry use only. Organophosphates and carbamates |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
| Company | MOLBASE (Shanghai) Biotechnology Co., Ltd. |
|---|---|
| Address | Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road, Xuhui District, Shanghai, China |
| Telephone | +86(21)64956998 |
| Fax | +86(21)54365166 |
1.5 Emergency phone number
| Emergency phone number | +86-400-6021-666 |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
2.Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Oral, Category 4
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |   |
|---|---|
| Signal word | Warning |
| Hazard statement(s) | H302 Harmful if swallowed H400 Very toxic to aquatic life H410 Very toxic to aquatic life with long lasting effects |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. |
| Response | P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell. P330 Rinse mouth. P391 Collect spillage. |
| Storage | none |
| Disposal | P501 Dispose of contents/container to ... |
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| diazinon | diazinon | 333-41-5 | none | 100% |
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
In case of skin contact
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
In case of eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
If swallowed
Rinse mouth. Give a slurry of activated charcoal in water to drink. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
LIQUID: POISONOUS IF SWALLOWED. Irritating to skin and eyes. (USCG, 1999)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Airway protection. Insure that a clear airway exists. Intubate the patients and aspirate the secretions with a large-bore suction device if necessary. Administer oxygen by mechanically assisted pulmonary ventilation if respiration is depressed. Improve tissue oxygenation as much as possible before administering atropine, so as to minimize the risk of ventricular fibrillation. In severe poisonings, it may be necessary to support pulmonary ventilation mechanically for several days. /Organophosphate pesticides/
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
Fire Extinguishing Media: dry chemical, foam, carbon dioxide.
5.2 Specific hazards arising from the chemical
Not flammable. POISONOUS GASES ARE PRODUCED WHEN HEATED. Oxides of sulfur and of phosphorus are generated in fires. (USCG, 1999)
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations.
6.3 Methods and materials for containment and cleaning up
In case of spill or leak: For small spills, sweep up keeping dust to a minimum, and place in a approved chemical container. Wash the spill area with water containing a strong detergent, absorb with pet litter or other absorbent material, sweep up, and place in a chemical container. Seal the container and handle in an approved manner. Flush the area with water to remove any residue. Do not allow wash water to contaminate water supplies. Wear appropriate PPE. /Diazinon 50W/
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Separated from strong oxidants, strong acids, bases and food and feedstuffs. Keep in a well-ventilated room.Store in original container only in cool, dry, well-ventilated, secure area out of reach of children and animals.
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
Recommended Exposure Limit: 10 Hour Time-Weighted Average: 0.1 mg/cu m [skin].
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
| Physical state | light to dark brown liquid |
|---|---|
| Colour | Colorless oil |
| Odour | Faint ester-like odor |
| Melting point/ freezing point | >120ºC (dec.) |
| Boiling point or initial boiling point and boiling range | 306ºC |
| Flammability | Class IIIA Combustible Liquid: Fl.P. at or above 60°C and below 93.33°C.Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. |
| Lower and upper explosion limit / flammability limit | no data available |
| Flash point | 2°C |
| Auto-ignition temperature | > 400°C. /Diazinon 50W/ |
| Decomposition temperature | at 120°C°C |
| pH | no data available |
| Kinematic viscosity | no data available |
| Solubility | In water:Slightly soluble. 0.004 g/100 mL |
| Partition coefficient n-octanol/water (log value) | log Kow = 3.81 |
| Vapour pressure | 0.0001 mm Hg (NIOSH, 2016) |
| Density and/or relative density | 1.117 |
| Relative vapour density | no data available |
| Particle characteristics | no data available |
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
More stable in alkaline formulations, then when at neutral or acid pH.
10.3 Possibility of hazardous reactions
PRACTICALLY NONFLAMMABLE.Organothiophosphates, such as DIAZINON, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. POISONOUS GASES ARE PRODUCED WHEN HEATED. Oxides of sulfur and of phosphorus are generated in fires (USCG, 1999). DIAZINON is incompatible with the following: Strong acids & alkalis, copper-containing compounds [Note: Hydrolyzes slowly in water & dilute acid.] (NIOSH, 2016).
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Strong acids and alkalis, copper containing compounds [Note: Hydrolyzes slowly in water and dilute acid].
10.6 Hazardous decomposition products
When heated to decomposition it emits very toxic fumes of /phosphorus oxides, sulfur oxides, and nitrogen oxides/.
11.Toxicological information
Acute toxicity
- Oral: LD50 Rat male oral 1340 mg/kg
- Inhalation: LC50 Rat inhalation >5540 mg/cu m 4 hr
- Dermal: LD50 Rat acute percutaneous > mg/kg 2150; rabbit acute percutaneous 540-650 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Not Likely to be Carcinogenic to Humans
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
- Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill) weight 1 g; Conditions: freshwater, static, 18°C, pH 7.1, hardness 44 mg/L CaCO3; Concentration: 362 ug/L for 24 hr (95% confidence interval: 270-480 ug/L) /92% purity formulation
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water Flea) age <24 hr neonate; Conditions: freshwater, static, 21°C; Concentration: 6.1 ug/L for 48 hr (95% confidence interval: 4.8-7.4 ug/L); Effect: intoxication, immobilization /100% purity formualtion
- Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green Algae); Conditions: freshwater, static; Concentration: 3700 ug/L for 7 days; Effect: population abundance /formulation
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
AEROBIC: Half-lives reported for diazinon in sterile (non-sterile) soils were 12.5 weeks (<1 week) in sandy loam and 6.5 weeks (2 weeks) in organic soil(1). Diazinon disappeared more quickly from unsterilized natural water (12 weeks) than from unsterilized distilled or sterilized natural water (>16 weeks), suggesting that degradation is both biological and chemical in nature in natural waters(2). Percent theoretical biological oxygen demand (BOD) was 16% for diazinon incubated with municipal sewage for 7.5-8.3 days(3). Diazinon, present at 100 mg/L, reached 0% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(4).
12.3 Bioaccumulative potential
BCF values were measured in the following species: topmouth gudgeon (Pseudodorasbora parva), 152, silver crucian carp (Cyprinus auratus), 36.6, carp (Cryprinus carpio), 65.1, guppy (Lebisters reticuatus) 17.5, crayfish (Procambarus clarkii), 4.9, red snail (Indoplanorbis exustus), 17.0, pond snail (Cipangopoludina malleata), 5.9(1); a fish (Fundulus heteroclutus), 10(2); species unreported, 35(3); carp, 120, rainbow trout, 63, loach, 26, shrimp, 3(4); sheepshead minnow, 200(5); eel(Anguilla anguilla) muscle and liver, 1600 and 800, respectively(6); perch 27(7); earthworm 8(8); fish from the Philipines, 12(9). According to a classification scheme(10), the range of experimental BCFs suggests the potential for bioconcentration in aquatic organisms is low to moderate(SRC).
12.4 Mobility in soil
The Koc for diazinon ranged from 40-432, and averaged 191 for 3 soils(1); in one sediment, the Koc was 250(1). For sandy loam(2.0% OM, pH 5.4), silt loam(1.4% OM, pH 7.0), silt loam(1.8% OM, pH 6.5) and sand(1.4% OM, pH 7.0), the Kocs were 1,539, 1,007, 1,653, and 1,842, respectively, with a recommended value of 1520(2). The Koc for diazinon was found to be 1589 in an Hungarian brown forest soil(3). The Koc for diazinon in two New Zealand topsoils was 165.22 and 324.49(4); the Koc in a New Zealand subsoil was 1447.47(4). According to a classification scheme(5), these experimental Koc values suggest that diazinon is expected to have moderate to low mobility in soil(SRC). Diazinon was given a leaching index of 2.0 (<20 cm movement/yr with 150 cm of annual rainfall)(6). Diazinon is reported to be fairly strongly adsorbed onto soil with low mobility(7).
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
14.Transport information
14.1 UN Number
| ADR/RID: UN1648 | IMDG: UN1648 | IATA: UN1648 |
14.2 UN Proper Shipping Name
| ADR/RID: ACETONITRILE |
| IMDG: ACETONITRILE |
| IATA: ACETONITRILE |
14.3 Transport hazard class(es)
| ADR/RID: 3 | IMDG: 3 | IATA: 3 |
14.4 Packing group, if applicable
| ADR/RID: III | IMDG: III | IATA: III |
14.5 Environmental hazards
| ADR/RID: yes | IMDG: yes | IATA: yes |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| diazinon | diazinon | 333-41-5 | none |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Not Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Not Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
16.Other information
Information on revision
| Creation Date | Aug 13, 2017 |
|---|---|
| Revision Date | Aug 13, 2017 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
