107-46-0 structure, C6H18OSi2

hexamethyldisiloxane

CAS No.

107-46-0

Formula:

C6H18OSi2

Basic Info

Hexamethyldisiloxane (HMDSO) is an organosilicon compound with the formula O[Si(CH3)3]2. This volatile colourless liquid is used as a solvent and as a reagent in organic synthesis. It is prepared by the hydrolysis of trimethylsilyl chloride. The molecule is the protypical disiloxane and resembles a subunit of polydimethylsiloxane.

Formula
C6H18OSi2
Molecular Weight
162.378
Exact Mass
162.09
LogP
2.6728
PSA
9.23
Synonyms

Disiloxane, hexamethyl-

H7310

ls-7130

CH7310

HX 18

Related CAS No. 104-46-0 (incorrect)

HMDSO

HMDO

os10

Fluka AG

kf96l

SF 0.65

expand collapse

Properties

Appearance & Physical State
Clear liquid
Density
0.764
Boiling Point
101ºC
Melting Point
-59ºC
Flash Point
-1ºC
Refractive Index
1.3765-1.3785
Water Solubility
insoluble
Stability
Stable, but moisture sensitive. Highly flammable. Incompatible with strong acids, strong bases, oxidizing agents.
Storage Condition
Flammables area
Vapor Density
>1 (vs air)

Safety Info

RTECS
JM9237000
Safety Statements
S16
WGK Germany
3
Risk Statements
R11
HS Code
29310095
RIDADR
UN 1993
Hazard Class
3
Packing Group
II
Caution Statement
P210; P273; P391; P403 + P235; P501
Hazard Codes
F
Hazard Declaration

H225; H410
Caution Statement

P210; P273; P391; P403 + P235; P501

Synthesis Route

1.Synthesis Route

80431-36-3

1013-88-3

107-46-0

110086-50-5
2.Synthesis Route

556-67-2

75-76-3

16029-98-4

107-46-0

107-52-8
3.Synthesis Route

556-67-2

107-46-0

541-02-6

107-52-8

540-97-6

Downstream Product

541-01-5

141-63-9

141-62-8

107-51-7

107-52-8
Home > Encyclopedia > Biochemicals and Pharmaceutical Chemicals > Pharmaceutical Intermediates > hexamethyldisiloxane

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