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Section 1. Chemical Product and Company Identification
    Dibucaine
    Common Name/
    Trade Name
    Dibucaine

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Section 3. Hazards Identification
    Potential Acute Health        Hazardous in case of ingestion. Slightly hazardous in case of skin contact (irritant), of eye contact (irritant),    
    Effects        of inhalation. Severe over-exposure can result in death.    
    CARCINOGENIC EFFECTS: Not available.
    Potential Chronic Health
    MUTAGENIC EFFECTS: Not available.
    Effects
    TERATOGENIC EFFECTS: Not available.
    DEVELOPMENTAL TOXICITY: Not available.
    The substance may be toxic to cardiovascular system, central nervous system (CNS).
    Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure
    to a highly toxic material may produce general deterioration of health by an accumulation in one or many
    human organs.

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Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water    
    for at least 15 minutes. Get medical attention if irritation occurs.
    Skin Contact        In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing    
    contaminated clothing and shoes. Cover the irritated skin with an emollient. Wash clothing before reuse.
    Thoroughly clean shoes before reuse. Get medical attention immediately.
    Serious Skin Contact        Not available.    
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.    
    Get medical attention immediately.
    Serious Inhalation        Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or    
    waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
    resuscitation. WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth
    resuscitation when the inhaled material is toxic, infectious or corrosive. Seek immediate medical attention.
    Ingestion        If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by    
    mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical
    attention immediately.
    Serious Ingestion        Not available.    

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Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        Not available.    
    Flammable Limits        Not available.    
    Products of Combustion        These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...).    
    Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
    Various Substances
    Explosion Hazards in        Risks of explosion of the product in presence of mechanical impact: Not available.    
    Presence of Various        Risks of explosion of the product in presence of static discharge: Not available.    
    Substances
    Fire Fighting Media        SMALL FIRE: Use DRY chemical powder.    
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    Special Remarks on        When heated to decomposition it emits toxic fumes of nitroxides.    
    Fire Hazards
    Special Remarks on Explosion Not available.
    Hazards
    Dibucaine

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Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container.    
    Large Spill        Poisonous solid.    
    Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray
    to reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all

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Section 7. Handling and Storage
    Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do
    Precautions
    not ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice
    immediately and show the container or the label.
    Storage        Keep container tightly closed. Keep container in a cool, well-ventilated area.    

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Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels    
    below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep
    exposure to airborne contaminants below the exposure limit.
    Personal Protection        Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.    
    Gloves.
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be
    a Large Spill        used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a    
    specialist BEFORE handling this product.
    Exposure Limits        Not available.    

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Section 9. Physical and Chemical Properties
    Physical state and appearance Solid. (Hygroscopic powder.)        Odor        Odorless.    
    Not available.
    Taste
    343.46 g/mole
    Molecular Weight
    Color        White.    
    Not applicable.
    pH (1% soln/water)
    Boiling Point        Not available.    
    Melting Point        62°C (143.6°F) - 65 C.    
    Critical Temperature        Not available.    
    Specific Gravity        Not available.    
    Not applicable.
    Vapor Pressure
    Vapor Density        13.1 (Air = 1)    
    Not available.
    Volatility
    Odor Threshold        Not available.    
    Water/Oil Dist. Coeff.        Not available.    
    Not available.
    Ionicity (in Water)
    Dispersion Properties        See solubility in water, diethyl ether.    
    Soluble in diethyl ether.
    Solubility
    Insoluble in cold water, hot water.
    Soluble in Ethanol, Chloroform, Petroleum Ether
    Dibucaine

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Section 10. Stability and Reactivity Data
    The product is stable.
    Stability
    Instability Temperature        Not available.    
    Excess heat
    Conditions of Instability
    Incompatibility with various Not available.
    substances
    Non-corrosive in presence of glass.
    Corrosivity
    Special Remarks on        Sensitive to light.    
    Reactivity
    Special Remarks on        Not available.    
    Corrosivity
    Will not occur.
    Polymerization

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Section 11. Toxicological Information
    Routes of Entry        Inhalation. Ingestion.    
    Toxicity to Animals        LD50: Not available.    
    LC50: Not available.
    Chronic Effects on Humans May cause damage to the following organs: cardiovascular system, central nervous system (CNS).
    Other Toxic Effects on        Hazardous in case of ingestion.    
    Humans        Slightly hazardous in case of skin contact (irritant), of inhalation.    
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on        Not available.    
    Chronic Effects on Humans
    Special Remarks on other        Acute Potential Health Effects:    
    Toxic Effects on Humans        Skin: May cause skin irritation. Can cause local numbness.    
    Eyes: May cause eye irritation.
    Inhalation: May cause respiratory tract irritation.
    Ingestion: Harmful if swallowed. Can cause vomiting, pallor, increased sweating, blurred or double vision.
    May affect behavior/'central nervous system (headache, staggering, convulsions, dizziness, confusion,
    drowsiness, trembling, shivering, anxiety, tiredness, weakness, excitement, somnolence), cardiovascular
    system (low blood pressure, irregular heartbeat, cardiac arresst). May also cause ringning or buzzing in the
    ears, feeling hot or cold, or numb.
    Medical Conditions Aggravated by Exposure: hypersensitivity to material; hear disease; chronic obstructive
    lung disease.

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Section 12. Ecological Information
    Ecotoxicity        Not available.    
    BOD5 and COD        Not available.    
    Possibly hazardous short term degradation products are not likely. However, long term degradation
    Products of Biodegradation
    products may arise.
    The products of degradation are less toxic than the product itself.
    Toxicity of the Products
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation
    Dibucaine

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Section 13. Disposal Considerations
    Waste Disposal        Waste must be disposed of in accordance with federal, state and local environmental    
    control regulations.

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Section 14. Transport Information
    DOT Classification        CLASS 6.1: Poisonous material.    
    UNNA: 1544 : Alkaloid, solid, n.o.s. (Dibucaine) PG: III
    Identification
    Not available.
    Special Provisions for
    Transport
    DOT (Pictograms)

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Section 15. Other Regulatory Information and Pictograms
    No products were found.
    Federal and State
    Regulations
    California        California prop. 65: This product contains the following ingredients for which the State of California has    
    Proposition 65        found to cause cancer which would require a warning under the statute: No products were found.    
    Warnings
    California prop. 65: This product contains the following ingredients for which the State of California has
    found to cause birth defects which would require a warning under the statute: No products were found.
    OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
    Other Regulations
    EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS
    no. 201-632-1)
    Canada: Not listed on Canadian Domestic Substance List (DSL) or Canadian Non- Domestic Substance
    List (NDSL).
    China: Not listed on National Inventory.
    Japan: Not listed on National Inventory (ENCS).
    Korea: Not listed on National Inventory (KECI).
    Philippines: Not listed on National Inventory (PICCS).
    Australia: Listed on AICS.
    WHMIS (Canada) CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
    Other Classifications
    DSCL (EEC)        This product is not classified        Not applicable.    
    according to the EU regulations.
    Health Hazard
    HMIS (U.S.A.)        2 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    2 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    E
    WHMIS (Canada)
    (Pictograms)
    DSCL (Europe)
    (Pictograms)
    Dibucaine
    TDG (Canada)
    (Pictograms)
    6
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Gloves.
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or
    equivalent. Wear appropriate respirator
    when ventilation is inadequate.

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SECTION 16 - ADDITIONAL INFORMATION
N/A