76-05-1 structure, C2HF3O2

trifluoroacetic acid

CAS No.

76-05-1

Formula:

C2HF3O2

Basic Info

Trifluoroacetic acid (TFA) is an organofluorine compound with the chemical formula CF3CO2H. It is a colorless liquid with a sharp odor similar to vinegar, but stronger in acidity. TFA is an analogue of acetic acid with the three hydrogen atoms replaced by three fluorine atoms. The acidity of TFA is approximately 34,000 times stronger than that of acetic acid due to the electronegativity of the trifluoromethyl group. TFA is widely used in organic chemistry for various purposes.

Formula
C2HF3O2
Molecular Weight
114.023
Exact Mass
113.993
LogP
0.6333
PSA
37.3
Synonyms

TFA

tri-fluoro-acetic acid

PERFLUOROACETATE

Acetic acid, trifluoro-

TRIFLUOROACETATE

WASH BUFFER

IPC-PFFA-2 TFA

trifluoroethanoic acid

perfluoroacetic acid

Trifluoroacetic acid

IPC-PFFA-2

BUFFER A

CF3COOH

expand collapse

Properties

Appearance & Physical State
clear liquid
Density
1.535
Boiling Point
72ºC
Melting Point
-15ºC
Flash Point
-3ºC
Refractive Index
1.3
Water Solubility
miscible
Stability
Stable. Incompatible with combustible material, strong bases, water, strong oxidizing agents. Non-combustible. Hygroscopic. May react violently with bases.
Storage Condition
2-8ºC
Vapor Density
3.9 (vs air)
Vapor Pressure
97.5 mm Hg ( 20 °C)

Safety Info

RTECS
AJ9625000
Safety Statements
S26-S27-S28-S45-S61-S9
WGK Germany
2
Risk Statements
R20; R35; R52/53
HS Code
2915900090
RIDADR
UN 2699
Hazard Class
8
Packing Group
I
Caution Statement
P261; P273; P280; P303 + P361 + P353; P304 + P340 + P310; P305 + P351 + P338
Hazard Codes
Hazard Declaration

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