618385-01-6 structure, C29H33FN2O4

Vorapaxar

CAS No.

618385-01-6

Formula:

C29H33FN2O4

Basic Info

Vorapaxar (brand name Zontivity, formerly known as SCH 530348) is a thrombin receptor (protease-activated receptor, PAR-1) antagonist based on the natural product himbacine, discovered by Schering-Plough and developed by Merck & Co.

Formula
C29H33FN2O4
Molecular Weight
492.582
Exact Mass
492.242
LogP
6.0204
PSA
77.52
Synonyms

Ethyl [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]vinyl}-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-y l]carbamate

((1r,3ar,4ar,6r,8ar,9s,9as)-9-((1e)-2-(5-(3-fluorophenyl)-2-pyridinyl)ethenyl)dodecahydro-1-methyl-3-oxonaphtho(2,3-c)furan-6-yl)-carbamic acid ethyl ester

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Properties

Density
1.25 g/cm3
Boiling Point
676ºC at 760 mmHg
Flash Point
362.632ºC
Refractive Index
1.594

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