60-41-3 structure, C42H46N4O8S

STRYCHNINE

CAS No.

60-41-3

Formula:

C42H46N4O8S

Basic Info

Strychnine is a highly toxic, colorless, bitter crystalline alkaloid used as a pesticide, particularly for killing small vertebrates such as birds and rodents. Strychnine, when inhaled, swallowed, or absorbed through eyes or mouth, causes a poisoning which results in muscular convulsions and eventually death through asphyxia. While it has no known medicinal effects, in the past the convulsant effect was believed to be beneficial in small doses. The most common source is from the seeds of the Strychnos nux-vomica tree.

Formula
C42H46N4O8S
Molecular Weight
766.902
Exact Mass
766.304
LogP
4.6188
PSA
148.54
Synonyms

Strychnine Sulfate BPC

L-STRYCHNINE

strychiniumsulfate

vampirol

Strychniniumsulfat

Strychnidin-10-one, sulfate (2:1)

STRYCHNINE ALKALOID

antivampire

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Properties

Boiling Point
559.9ºC at 760 mmHg
Melting Point
284-286ºC(lit.)
Flash Point
292.4ºC

Safety Info

RTECS
WL2550000
Safety Statements
S36/37; S45; S60; S61
WGK Germany
3
Risk Statements
R27/28; R50/53; R26/28
RIDADR
UN 1692 6.1/PG 1
Hazard Class
6.1(a)
Packing Group
I
Hazard Codes

MSDS

SDS 1.0
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SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name STRYCHNINE

1.2 Other means of identification

Product number -
Other names Strychnine Sulfate BPC

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

Company MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road,
Xuhui District, Shanghai, China
Telephone +86(21)64956998
Fax +86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-400-6021-666
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 2

Acute toxicity - Inhalation, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Danger

Hazard statement(s)

H300 Fatal if swallowed

H330 Fatal if inhaled

H410 Very toxic to aquatic life with long lasting effects

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P284 [In case of inadequate ventilation] wear respiratory protection.

P273 Avoid release to the environment.

Response

P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/…

P321 Specific treatment (see ... on this label).

P330 Rinse mouth.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P310 Immediately call a POISON CENTER/doctor/…

P320 Specific treatment is urgent (see ... on this label).

P391 Collect spillage.

Storage

P405 Store locked up.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
STRYCHNINE STRYCHNINE 60-41-3 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

no data available

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state no data available
Colour no data available
Odour no data available
Melting point/ freezing point 284-286ºC(lit.)
Boiling point or initial boiling point and boiling range 559.9ºC at 760 mmHg
Flammability no data available
Lower and upper explosion limit / flammability limit no data available
Flash point 292.4ºC
Auto-ignition temperature no data available
Decomposition temperature no data available
pH no data available
Kinematic viscosity no data available
Solubility no data available
Partition coefficient n-octanol/water (log value) no data available
Vapour pressure no data available
Density and/or relative density no data available
Relative vapour density no data available
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

no data available

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

no data available

11.Toxicological information

Acute toxicity

  • Oral: no data available
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: no data available
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

no data available

12.3 Bioaccumulative potential

no data available

12.4 Mobility in soil

no data available

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN1692 IMDG: UN1692 IATA: UN1692

14.2 UN Proper Shipping Name

ADR/RID: STRYCHNINE or STRYCHNINE SALTS
IMDG: STRYCHNINE or STRYCHNINE SALTS
IATA: STRYCHNINE or STRYCHNINE SALTS

14.3 Transport hazard class(es)

ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1

14.4 Packing group, if applicable

ADR/RID: I IMDG: I IATA: I

14.5 Environmental hazards

ADR/RID: yes IMDG: yes IATA: yes

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
STRYCHNINE STRYCHNINE 60-41-3 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Not Listed.
China Catalog of Hazardous chemicals 2015 Not Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Not Listed.

16.Other information

Information on revision

Creation Date Aug 18, 2017
Revision Date Aug 18, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
MSDS
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Section 1. Chemical Product and Company Identification
    Strychnine Hemisulfate
    Common Name/
    Trade Name
    Manufacturer
    Commercial Name(s)
    Synonym
    Chemical Name
    Chemical Family
    Strychnine Hemisulfate

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at    
    least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.
    Skin Contact        Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.    
    Cold water may be used.
    Serious Skin Contact        Not available.    
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get    
    medical attention.
    Serious Inhalation        Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or    
    waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
    resuscitation. Seek medical attention.
    Ingestion        If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by    
    mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical
    attention immediately.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product Non-flammable.
    Auto-Ignition Temperature Not applicable.
    Flash Points        Not applicable.    
    Flammable Limits        Not applicable.    
    Products of Combustion        Not available.    
    Fire Hazards in Presence of Not applicable.
    Various Substances
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    of Various Substances        Risks of explosion of the product in presence of static discharge: Not available.    
    Fire Fighting Media        Not applicable.    
    and Instructions
    Special Remarks on        Not available.    
    Fire Hazards
    Special Remarks on Explosion Not available.
    Hazards

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container.    
    Large Spill
    Poisonous solid.
    Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to
    disposal.
    Strychnine Hemisulfate

Section 7. Handling and Storage
    Precautions        Do not ingest. Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear    
    suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label.
    Keep away from incompatibles such as acids, alkalis.
    Storage        Keep container tightly closed. Keep container in a cool, well-ventilated area.    

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.    
    Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
    a Large Spill        to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist    
    BEFORE handling this product.
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid. (Powdered solid.)        Odor        Not available.    
    Taste        Bitter.    
    Molecular Weight        383.5 g/mole    
    Color        Off-white.    
    pH (1% soln/water)        Not available.    
    Not available.
    Boiling Point
    Melting Point        Not available.    
    Not available.
    Critical Temperature
    Specific Gravity        Not available.    
    Vapor Pressure        Not applicable.    
    Vapor Density        Not available.    
    Volatility        Not available.    
    Odor Threshold        Not available.    
    Water/Oil Dist. Coeff.        Not available.    
    Ionicity (in Water)        Not available.    
    Dispersion Properties        See solubility in water.    
    Solubility        Soluble in cold water.    

Section 10. Stability and Reactivity Data
    The product is stable.
    Stability
    Instability Temperature        Not available.    
    Conditions of Instability        Excess heat, incompatible materials, dust generation    
    Reactive with acids, alkalis.
    Incompatibility with various
    substances
    Not available.
    Corrosivity
    Strychnine Hemisulfate
    Incompatible with alkalies, alkali carbonates, bicarbonates, benzoates, dichromates, bromides, iodides, tannic and
    Special Remarks on
    Reactivity        picric acids, salicylates, borax, gold chlorides, piperazine.    
    Not available.
    Special Remarks on
    Corrosivity
    Polymerization        Will not occur.    

Section 11. Toxicological Information
    Routes of Entry        Inhalation. Ingestion.    
    Toxicity to Animals        Acute oral toxicity (LD50): 2.6 mg/kg [Rat].    
    Chronic Effects on Humans Not available.
    Other Toxic Effects on        Very hazardous in case of ingestion, of inhalation.    
    Humans        Slightly hazardous in case of skin contact (irritant).    
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on        Not available.    
    Chronic Effects on Humans
    Special Remarks on other        Acute Potential Health Effects:    
    Toxic Effects on Humans        Skin: May cause skin irritation.    
    Eyes: May cause eye irritation.
    Inhalation: Inhalation of dust or fumes (when heated to decompositioni) can result in respiratory tract irritation with
    chemical pneumonitis, bronchospasm, or noncardiogenic pulmonary edema. It is rapidly absorbed from the
    respiratory tract, and intranasally resulting in toxicity within 30 minutes.
    Ingestion: May be fatal if swallowed. It is rapidly absorbed from the gastrointestinal tract.
    Styrchnine poisoning causes nausea, vomiting, and profuse diarrhea. It can affect the cardiovascular system,
    respiration, behavior/central nevrous system, blood and brain. It is a central nervous system stimulant which can
    cause severe headaches, and tonic convulsions. A prodromal syndrome including muscular cramps, stiffness,
    and agitation is commonly reported prior to the onset of convulsions; generalized convulsions may be the initial
    event. Generalized convulsions usually occur within 15 to 60 minutes after acute ingestion and within 30 minutes
    after being absorbe from the respiratory tract. Hypothermia (low body temperature), hypotension (low blood
    pressure), and hypertension (high blood pressure) have been noted in Strychnine poisoning. Hypotension
    appears to be due to marked acidosis and hypoxia in individuals with severe poisoning. Severe and prolonged
    convulsions may result in marked hyperthermia (high body temperature). Temperatures as high as 43 C. have
    been reported. Bilateral horizontal pendular nystagmus (involuntary eye movement) may occur. Bradycardia
    (slow heartbeat) can be associated with hypotension and tachycardia (fast heartbeat) as well as tachypena (fast,
    shallow breathing)commonly accompanies agitation and neuromuscular hyperactivity. The affected individual may
    complain of chest tightness, difficulty breathing, and a feeling of suffocation. Cardiac arrest may result from
    severe or prolonged convulsions or respiratory arrest. With severe or prolonged convulsions, sustained
    contractions of the chest wall muscles and diaphragm may lead to respiratory paralysis. A period of flaccid
    paralysis with apnea (no breathing) and cyanosis (bluish discoloration) may also occur after the period of
    convulsions. Renal failure, rapid breakdown of skeletal muscle tissue (Rhabdomyolysis), multiple organ failure
    (including liver necrosis) may also occur. Death is usually due to respiratory failure.

Section 12. Ecological Information
    Not available.
    Ecotoxicity
    BOD5 and COD        Not available.    
    Products of Biodegradation        Possibly hazardous short term degradation products are not likely. However, long term degradation products may    
    arise.
    Toxicity of the Products        The products of degradation are less toxic than the product itself.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation
    Strychnine Hemisulfate

Section 13. Disposal Considerations
    Waste Disposal        Waste must be disposed of in accordance with federal, state and local environmental    
    control regulations.

Section 14. Transport Information
    DOT Classification        CLASS 6.1: Poisonous material.    
    : Strychnine salt (styrchnine hemisulfate) UNNA: 1692 PG: I
    Identification
    Not available.
    Special Provisions for
    Transport
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    Illinois toxic substances disclosure to employee act: Strychnine Hemisulfate
    Federal and State
    Illinois chemical safety act: Strychnine Hemisulfate
    Regulations
    New York release reporting list: Strychnine Hemisulfate
    Pennsylvania RTK: Strychnine Hemisulfate
    Massachusetts RTK: Strychnine Hemisulfate
    Massachusetts spill list: Strychnine Hemisulfate
    New Jersey: Strychnine Hemisulfate
    New Jersey spill list: Strychnine Hemisulfate
    Louisiana RTK reporting list: Strychnine Hemisulfate
    SARA 302/304/311/312 extremely hazardous substances: Strychnine Hemisulfate
    CERCLA: Hazardous substances.: Strychnine Hemisulfate: 10 lbs. (4.536 kg)
    California        California prop. 65: This product contains the following ingredients for which the State of California has found    
    Proposition 65        to cause cancer which would require a warning under the statute: No products were found.    
    Warnings
    California prop. 65: This product contains the following ingredients for which the State of California has found
    to cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).    
    EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No.
    200-47-7).
    Canada: Not listed on Canadian Domestic Substance List (DSL) or Canadian Non-Domestic Substances List
    (NDSL)
    China: Not listed on National Inventory.
    Japan: Not listed on National Inventory (ENCS).
    Korea: Not listed on National Inventory (KECI).
    Philippines: Not listed on National Inventory (PICCS).
    Australia: Not listed on AICS.
    WHMIS (Canada) CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC).
    Other Classifications
    DSCL (EEC)        R28- Very toxic if swallowed.        S28- After contact with skin, wash immediately    
    with plenty of [***]
    S36/37- Wear suitable protective clothing and
    gloves.
    S45- In case of accident or if you feel unwell,
    seek medical advice immediately (show the
    label where possible).
    Strychnine Hemisulfate
    Health Hazard
    HMIS (U.S.A.)        3 National Fire Protection    
    0 Flammability
    0 Association (U.S.A.)
    Fire Hazard
    3 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    E
    WHMIS (Canada)
    (Pictograms)
    DSCL (Europe)
    (Pictograms)
    TDG (Canada)
    (Pictograms)
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Gloves.
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or
    equivalent. Wear appropriate respirator
    when ventilation is inadequate.
    Safety glasses.


SECTION 16 - ADDITIONAL INFORMATION
N/A

Spectrum

NMR Spectrum 1H NMR : Predict
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Toxicity

ACUTE TOXICITY DATA
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Type of Test
LDLo - Lowest published lethal dose
Exposure Route
Oral
Species Observed
Human - man
Dose/Duration
37 mg/kg
Toxic Effects
Behavioral--convulsions or effect on seizure threshold<br>Cardiac--pulse rate<br>Lungs, Thorax, or Respiration--pleural thickening
Reference
Journal of Analytical Toxicology. (Preston Pub. Inc., POB 48312, Niles, IL 60648) V.1- 1977- Volume(issue)/page/year: 10,120,1986
ACUTE TOXICITY DATA
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Type of Test
LD50 - Lethal dose, 50 percent kill
Exposure Route
Oral
Species Observed
Rodent - rat
Dose/Duration
2600 ug/kg
Toxic Effects
Details of toxic effects not reported other than lethal dose value--
Reference
Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 31,113,1942
ACUTE TOXICITY DATA
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Type of Test
LD50 - Lethal dose, 50 percent kill
Exposure Route
Intraperitoneal
Species Observed
Rodent - rat
Dose/Duration
1 mg/kg
Toxic Effects
Behavioral--convulsions or effect on seizure threshold
Reference
Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,1125,1973

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