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Section 1. Chemical Product and Company Identification
    Pergolide Mesylate
    Common Name/
    Trade Name
    Pergolide Mesylate

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Section 4. First Aid Measures
    Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least
    Eye Contact
    15 minutes. Cold water may be used. Get medical attention.
    In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated
    Skin Contact
    clothing and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse.
    Thoroughly clean shoes before reuse. Get medical attention immediately.
    Serious Skin Contact        Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate    
    medical attention.
    Inhalation        If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get    
    medical attention immediately.
    Serious Inhalation        Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband.    
    WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth resuscitation when the inhaled
    material is toxic, infectious or corrosive. Seek immediate medical attention.
    If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to
    Ingestion
    an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention
    immediately.
    Not available.
    Serious Ingestion

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Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Not available.
    Flash Points
    Not available.
    Flammable Limits
    These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2, SO3...).
    Products of Combustion
    Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
    Non-flammable in presence of shocks.
    Various Substances
    Risks of explosion of the product in presence of mechanical impact: Not available.
    Explosion Hazards in
    Slightly explosive in presence of open flames and sparks.
    Presence of Various
    Substances
    SMALL FIRE: Use DRY chemical powder.
    Fire Fighting Media
    LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
    and Instructions
    As with most organic solids, fire is possible at elevated temperatures
    Special Remarks on
    Fire Hazards
    Fine dust dispersed in air in sufficient concentrations, and in the presences of an ignition source is a potential dust
    Special Remarks on
    explosion hazard.
    Explosion Hazards

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Section 6. Accidental Release Measures
    Use appropriate tools to put the spilled solid in a convenient waste disposal container.
    Small Spill
    Poisonous solid.
    Large Spill
    Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to reduce
    for assistance on disposal.
    Pergolide Mesylate

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Section 7. Handling and Storage
    Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
    Precautions
    ingest. Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable
    respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid
    contact with skin and eyes.
    Keep container tightly closed. Keep container in a cool, well-ventilated area. Sensitive to light. Store in
    Storage
    light-resistant containers.

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Section 8. Exposure Controls/Personal Protection
    Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
    Engineering Controls
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.    
    Personal Protection in Case Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to
    avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE
    of a Large Spill
    handling this product.
    Not available.
    Exposure Limits

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Section 9. Physical and Chemical Properties
    Solid.        Perceptible odor (Slight.)    
    Physical state and        O dor    
    appearance
    Not available.
    Taste
    410.64 g/mole
    Molecular Weight
    White.
    Color
    Not available.
    pH (1% soln/water)
    Not available.
    Boiling Point
    Decomposition temperature: 225°C (437°F)
    Melting Point
    Not available.
    Critical Temperature
    Not available.
    Specific Gravity
    Not applicable.
    Vapor Pressure
    Not available.
    Vapor Density
    Not available.
    Volatility
    Not available.
    Odor Threshold
    Not available.
    Water/Oil Dist. Coeff.
    Not available.
    Ionicity (in Water)
    See solubility in water.
    Dispersion Properties
    Very slightly soluble in cold water.
    Solubility
    Soluble in most organic substances
    Pergolide Mesylate

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Section 10. Stability and Reactivity Data
    The product is stable.
    Stability
    Not available.
    Instability Temperature
    Conditions of Instability Excess heat, dust generation, incompatible materials
    Incompatibility with various Not available.
    substances
    Not available.
    Corrosivity
    Not available.
    Special Remarks on
    Reactivity
    Not available.
    Special Remarks on
    Corrosivity
    Will not occur.
    Polymerization

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Section 11. Toxicological Information
    Inhalation. Ingestion.
    Routes of Entry
    Toxicity to Animals        Acute oral toxicity (LD50): 8.4 mg/kg [Rat].    
    Chronic Effects on Humans May cause damage to the following organs: cardiovascular system, central nervous system (CNS).
    Very hazardous in case of ingestion, .
    Other Toxic Effects on
    Humans        Hazardous in case of skin contact (irritant), of inhalation (lung irritant).    
    Not available.
    Special Remarks on
    Toxicity to Animals
    May cause adverse reproductive effects and birth defects (teratogenic)
    Special Remarks on
    Chronic Effects on Humans
    Acute Potential Health Effects:
    Special Remarks on other
    Skin: Causes skin irritation.
    Toxic Effects on Humans
    Eyes: Causes eye irritation.
    Inhalation: Harmful if inhaled. Causes respiratory tract irritation.
    Ingestion: May be fatal if swallowed. Causes gastrointestinal tract irritation with nausea, and vomiting. May also
    affect behavior/central nervous system (temor, excitement, hallucinations, aggression, convulsions), metabolsim, and
    respiratory system (respiratory stimulation), cardiovascular system, eyes (ptosis, pupillary dilation).
    Chronic Potential Health Effects:
    Ingestion: Repeated or prolonged ingestion may also affect behavior/central nervous system), blood (red and white
    blood cell count), metabolism (weight loss), prostate, ovaries (changes in prostate and ovarian weight).

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Section 12. Ecological Information
    Not available.
    Ecotoxicity
    Not available.
    BOD5 and COD
    Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may
    arise.
    The products of degradation are less toxic than the product itself.
    Toxicity of the Products
    of Biodegradation
    Not available.
    Special Remarks on the
    Products of Biodegradation
    Pergolide Mesylate

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Section 13. Disposal Considerations
    Waste must be disposed of in accordance with federal, state and local environmental control
    Waste Disposal
    regulations.

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Section 14. Transport Information
    CLASS 6.1: Poisonous material.
    DO T Cl assi fi cati on
    UNNA: 2811 : Toxic Solid, Organic, n.o.s. (Pergolide Mesylate) PG: II
    Identification
    Not available.
    Special Provisions for
    Transport
    DO T (Pi ctograms)

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Section 15. Other Regulatory Information and Pictograms
    No products were found.
    Federal and State
    Regulations
    California prop. 65: This product contains the following ingredients for which the State of California has found to
    California
    cause cancer which would require a warning under the statute: No products were found.
    Proposition 65
    Warnings
    California prop. 65: This product contains the following ingredients for which the State of California has found to
    cause birth defects which would require a warning under the statute: No products were found.
    Other Regulations        OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).    
    EINECS: This product is not on the European Inventory of Existing Commercial Chemical Substances.
    Canada: Not listed on Canadian Domestic Substance List (DSL) or Canadian Non- Domestic Substance List (NDSL).
    China: Not listed on National Inventory.
    Japan: Not listed on National Inventory (ENCS).
    Korea: Not listed on National Inventory (KECI).
    Philippines: Not listed on National Inventory (PICCS).
    Australia: Not listed on AICS.
    WHMIS (Canada) It has not been classified by the Service du repertoire toxicologique. However, it may fall
    Other Classifications
    into the CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC).
    R26/27/28- Very toxic by inhalation, in        S22- Do not breathe dust.    
    DSCL (EEC)
    contact with skin and if swallowed.        S26- In case of contact with eyes, rinse    
    R36/37/38- Irritating to eyes, respiratory        immediately with plenty of water and seek    
    system and skin.        medical advice.    
    R40- Limited evidence of a        S36/37/39- Wear suitable protective clothing,    
    carcinogenic effect.        gloves and eye/face protection.    
    R60- May impair fertility.        S38- In case of insufficient ventilation, wear    
    R63- Possible risk of harm to the unborn        suitable respiratory equipment.    
    child.        S45- In case of accident or if you feel unwell,    
    seek medical advice immediately (show the
    label where possible).
    HMIS (U.S.A.)        Health Hazard        3 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    3 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    E
    WHMIS (Canada)
    (Pictograms)
    Pergolide Mesylate
    DSCL (Europe)
    (Pictograms)
    TDG(Canada)
    (Pictograms)
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Gloves.
    Lab coat.
    Dust respirator. Be sure to use an
    approved/certified respirator or equivalent.

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SECTION 16 - ADDITIONAL INFORMATION
N/A