95-47-6 structure, C8H10

o-Xylene

CAS No.

95-47-6

Formula:

C8H10

Basic Info

o-Xylene (ortho-xylene) is an aromatic hydrocarbon, based on benzene with two methyl substituents bonded to adjacent carbon atoms in the aromatic ring (the ortho configuration).
It is a constitutional isomer of m-xylene and p-xylene.
o-Xylene is largely used in the production of phthalic anhydride, and is generally extracted by distillation from a mixed xylene stream in a plant primarily designed for p-xylene production.

Formula
C8H10
Molecular Weight
106.165
Exact Mass
106.078
LogP
2.3034
PSA
0
Synonyms

Benzene, 1,2-dimethyl-

1,2-dimethyl-benzene

Orthoxylene

ortho-Dimethylbenzene

O-Dimethylbenzene

1,2-Xylene

1,2-Dimethylbenzene

o-Xylol

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Properties

Appearance & Physical State
colourless liquid
Density
0.879g/cm3
Boiling Point
143-145ºC
Melting Point
-3ºC
Flash Point
31ºC
Refractive Index
1.505
Stability
Stable. Incompatible with oxidizing agents. Flammable. Hygroscopic.
Storage Condition
0-6ºC
Vapor Density
3.7 (vs air)
Vapor Pressure
<0.1 atm ( 21.1 °C)

Safety Info

RTECS
ZE2450000
Safety Statements
S25
WGK Germany
2
Risk Statements
R10; R20/21; R38
HS Code
2902410000
RIDADR
UN 1307
Hazard Class
3
Packing Group
II
Caution Statement
P210; P261; P273; P301 + P310; P302 + P352 + P312; P331
Hazard Codes

MSDS

SDS 1.0
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SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name o-Xylene

1.2 Other means of identification

Product number -
Other names Benzene, 1,2-dimethyl-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Fuels and fuel additives,Intermediates
Uses advised against no data available

1.4 Supplier's details

Company MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road,
Xuhui District, Shanghai, China
Telephone +86(21)64956998
Fax +86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-400-6021-666
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Flammable liquids, Category 3

Acute toxicity - Dermal, Category 4

Skin irritation, Category 2

Acute toxicity - Inhalation, Category 4

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Warning

Hazard statement(s)

H226 Flammable liquid and vapour

H312 Harmful in contact with skin

H315 Causes skin irritation

H332 Harmful if inhaled

Precautionary statement(s)
Prevention

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

P233 Keep container tightly closed.

P240 Ground and bond container and receiving equipment.

P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.

P242 Use non-sparking tools.

P243 Take action to prevent static discharges.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P264 Wash ... thoroughly after handling.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

Response

P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].

P370+P378 In case of fire: Use ... to extinguish.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P312 Call a POISON CENTER/doctor/…if you feel unwell.

P321 Specific treatment (see ... on this label).

P362+P364 Take off contaminated clothing and wash it before reuse.

P332+P313 If skin irritation occurs: Get medical advice/attention.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

Storage

P403+P235 Store in a well-ventilated place. Keep cool.

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
o-Xylene o-Xylene 95-47-6 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest. Refer for medical attention.

In case of skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap.

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rinse mouth. Do NOT induce vomiting. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

Vapors cause headache and dizziness. Liquid irritates eyes and skin. If taken into lungs, causes severe coughing, distress, and rapidly developing pulmonary edema. If ingested, causes nausea, vomiting, cramps, headache, and coma. Can be fatal. Kidney and liver damage can occur. (USCG, 1999)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Immediate First Aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Aromatic hydrocarbons and related compounds/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.

5.2 Specific hazards arising from the chemical

Behavior in Fire: Vapor is heavier than air and may travel considerable distance to a source of ignition and flash back. (USCG, 1999)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Remove all ignition sources. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

6.3 Methods and materials for containment and cleaning up

ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up: Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Fireproof. Separated from strong oxidants and strong acids.Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Storage class (TRGS 510): Flammable liquids.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 100 ppm (435 mg/cu m).

Recommended Exposure Limit: 15 Min Short-Term Exposure Limit: 150 ppm (655 mg/cu m).

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state colourless liquid
Colour Colorless liquid
Odour Sweet
Melting point/ freezing point -3ºC
Boiling point or initial boiling point and boiling range 143-145°C(lit.)
Flammability Class IC Flammable Liquid: Fl.P. at or above 22.78°C and below 37.78°C.Flammable.
Lower and upper explosion limit / flammability limit Percent vol: lower 0.9; upper 6.7
Flash point 31°C
Auto-ignition temperature 463.89°C
Decomposition temperature no data available
pH no data available
Kinematic viscosity 0.760 mPa.s at 25°C
Solubility Insoluble
Partition coefficient n-octanol/water (log value) log Kow = 3.12
Vapour pressure <0.1 atm ( 21.1 °C)
Density and/or relative density 0.879g/mLat 20°C(lit.)
Relative vapour density 3.7 (vs air)
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

A very dangerous fire hazard when exposed to heat or flame.As a result of flow, agitation, etc., electrostatic charges can be generated.O-XYLENE may react with oxidizing materials. .

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Incompatible materials: Oxidizing agents.

10.6 Hazardous decomposition products

Hazardous decomposition products formed under fire conditions - Carbon oxides.

11.Toxicological information

Acute toxicity

  • Oral: LD50 Rat oral 3608 mg/kg bw
  • Inhalation: LC50 Rat inhalation 6350 ppm (27.4 mg/L)/4 hr /From table/
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Evaluation: There is inadequate evidence in humans for the carcinogenicity of xylenes. There is inadequate evidence in experimental animals for the carcinogenicity of xylenes. Overall classification: Xylenes are not classifiable as to their carcinogenicity to humans (Group 3)./Xylenes, o,m,p isomers/

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill, weight 1.1 g); Conditions: freshwater, flow through, 17.2°C (16.5-18.4°C), pH 7.39 (6.84-7.80), hardness 44.7 mg/L CaCO3 (40.8-47.6 mg/L CaCO3), alkalinity 43.0 mg/L CaCO3 (40.4-49.5 mg/L CaCO3), dissoved oxygen 8.7 mg/L (4.8-10.7 mg/L); Concentration: 16100 ug/L for 96 hr (95% confidence interval: 11600-22400 ug/L)
  • Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea); Conditions: freshwater, static; Concentration: 1000 ug/L for 24 hr; Effect: intoxication, immobilization
  • Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green algae); Conditions: freshwater, static; Concentration: 4700 ug/L for 72 hr; Effect: growth, general /formulated product
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: 2-Xylene has been observed to biodegrade in standard biodegradability tests using various inocula including sewage, activated sludge and sea water(1-4). It was completely degraded in 8 days in groundwater in a gasoline-oil mixture; the acclimation period was 3-4 days(5). In laboratory experiments designed to simulate saturated-flow conditions typical of a river water/ground water infiltration system, degradation was rapid with 70% removal in the first 1.5 cm of the column after 10 days of operation under aerobic conditions(6). Another investigator found that 2-xylene was readily biodegraded (33 mg/day loss) in shallow ground water in an unconfined sand aquifer when oxygen was present(7). As the available oxygen was consumed, the rate of degradation decreased(7). 2-Xylene degraded in two steps with adaptation periods of 14 and 49 days, using an unpolluted groundwater seed(8,9). Xylene (mixed isomers), present at 100 mg/L, reached 100% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test which classified xylene as readily biodegradable(10). Using OECD Guideline 301F (Ready Biodegradability: Manometric Respirometry Test) with a mixture of sewage, soil and natural water inoculum, 2-xylene reached 90-94% of its O2 consumption in 28 days which classified xylene as readily biodegradable in two separate studies(11). An OECD Guideline 301F test using activated sludge found >60% degradation in 28 days, but degradation failed the 10-day window for being readily biodegradable(11).

12.3 Bioaccumulative potential

A log BCF of 1.15 (BCF of 14) was measured in goldfish(1) and a log BCF of 1.3 was measured in eels (Anguilla japonica)(2) for 2-xylene. According to a classification scheme(3), these BCF values indicate that bioconcentration in aquatic organisms is low(SRC). A log BCF value was measured in clams (log BCF of 0.79)(4). A log bioconcentration value of 2.3 ((ug/kg)/(ug/L)) was determined in a green alga, Selenastrium capricornutum(5).

12.4 Mobility in soil

Koc values measured for 2-xylene in various soils (% organic matter) were 24 in Wendover silty clay (16.2%), 26 in Vaudreil sand loam (10.0%), 68 in St. Thomas sand (3.1%), and 138 in Grimsby silt loam (1.0%)(1). Batch adsorption tests, using three solid sandy aquifer materials gave a Koc of 129(2). The Koc for 2-xylene in surface sediments collected from the central Tamar estuary in the UK was 25.4(3). The Koc values for 2-xylene in two river sediments (% organic matter 6.5-16.9 wt%) was 209 and 251, respectively(4). According to a classification scheme(5), these measured Koc values suggests that 2-xylene is expected to have very high to moderate mobility in soil. Using OECD Guideline 121 (estimating Koc via HPLC), the Koc of 2-xylene was estimated to be 537(6). Concentration enhancement has been observed for 2-xylene in a dune-infiltration project on the Rhine River(7); however, no 2-xylene reached groundwater under a rapid infiltration site(8). The log Koc for 2-xylene in coal sediment (% organic matter 52 wt%) was 2.40(4).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN1307 IMDG: UN1307 IATA: UN1307

14.2 UN Proper Shipping Name

ADR/RID: XYLENES
IMDG: XYLENES
IATA: XYLENES

14.3 Transport hazard class(es)

ADR/RID: 3 IMDG: 3 IATA: 3

14.4 Packing group, if applicable

ADR/RID: III IMDG: III IATA: III

14.5 Environmental hazards

ADR/RID: no IMDG: no IATA: no

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
o-Xylene o-Xylene 95-47-6 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 17, 2017
Revision Date Aug 17, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
MSDS
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Name: Custom Oil Standard-Single Element Solution Material Safety Data Sheet
Synonym: None
CAS: 95-47-6
Section 1 - Chemical Product   MSDS Name:Custom Oil Standard-Single Element Solution Material Safety Data Sheet
Synonym:None

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
95-47-6 o-Xylene 8.0-10.0 202-422-2
Hazard Symbols: XN
Risk Phrases: 10 20/21 38

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Flammable. Harmful by inhalation and in contact with skin.
Irritating to skin.
Potential Health Effects
Eye:
Causes severe eye irritation. Splashes of xylene in human eyes generally cause transient superficial injury.
Skin:
May be harmful if absorbed through the skin. Xylene contact causes defatting of the skin with irritation, dryness, and cracking.
Blistering may occur, particularly if exposure to concentrated xylene is prolonged and the exposed area of skin is occluded.
Ingestion:
Aspiration hazard. May cause irritation of the digestive tract. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea.
Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. May cause effects similar to those of acute inhalation.
Inhalation:
Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache, dizziness, unconsciousness and coma. Prolonged exposure may result in dizziness and general weakness. Irritation may lead to chemical pneumonitis and pulmonary edema. May cause liver and kidney damage. Causes irritation of mucous membrane. Exposure may cause blood abnormalities. Odor thresholds ranging from 0.07 to 40 ppm have been reported for xylenes.
Chronic:
Chronic exposure to xylene may cause defatting dermatitis, reversible eye damage, dyspnea (labored breathing), confusion, dizziness, apprehension, memory loss, headache, tremors, weakness, anorexia, nausea, ringing in the ears, irritability, thirst, mild changes in liver function, kidney impairment, anemia, and hyperplasia, but not destruction, of the bone marrow.

Section 4 - FIRST AID MEASURES
  Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
Potential for aspiration if swallowed. Get medical aid immediately.
Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Flammable liquid and vapor. Vapors may form an explosive mixture with air. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas. This liquid floats on water and may travel to a source of ignition and spread fire. May accumulate static electricity.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Water may be ineffective. This material is lighter than water and insoluble in water. The fire could easily be spread by the use of water in an area where the water cannot be contained. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces. U.S. regulations require reporting spills and releases to soil, water and air in excess of reportable quantities. This material creates a fire hazard because it floats on water. If possible, try to contain floating material.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate ventilation. Keep away from heat, sparks and flame.
Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Keep container closed when not in use. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from strong acids.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 95-47-6: United Kingdom, WEL - TWA: 50 ppm TWA; 220 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 441 mg/m3 STEL United States OSHA: 100 ppm TWA; 435 mg/m3 TWA (listed under Xyl (o-, m-, p- isomers)).
Belgium - TWA: 50 ppm VLE; 221 mg/m3 VLE Belgium - STEL: 150 ppm VLE; 442 mg/m3 VLE France - VME: (listed as xylenes (o-, m-, p- isomers)): 100 ppm V 435 mg/m3 VME France - VLE: (listed as xylenes (o-, m-, p- isomers)): 150 ppm V 650 mg/m3 VLE Germany: (listed as xylenes (o-, m-, p- isomers)): 100 ppm VME; 4 mg/m3 VME Germany: (listed as xylenes (o-, m-, p- isomers)): Skin absorber Japan: 50 ppm OEL; 217 mg/m3 OEL Malaysia: 199 ppm TWA; 434 mg/m3 TWA Netherlands: (listed as xylenes (o-, m-, p- isomers)): 50 ppm MAC 210 mg/m3 MAC Russia: (listed as xylenes (o-, m-, p- isomers)): 50 mg/m3 TWA Spain: 50 ppm VLA-ED; 221 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 442 mg/m3 VLA-EC CAS# 100-41-4: United Kingdom, WEL - TWA: 100 ppm TWA; 441 mg/m3 TWA United Kingdom, WEL - STEL: 125 ppm STEL; 552 mg/m3 STEL United States OSHA: 100 ppm TWA; 435 mg/m3 TWA Belgium - TWA: 100 ppm VLE; 442 mg/m3 VLE Belgium - STEL: 125 ppm VLE; 551 mg/m3 VLE France - VME: 100 ppm VME; 435 mg/m3 VME Germany: 100 ppm TWA; 440 mg/m3 TWA Germany: Skin absorber Japan: 50 ppm OEL; 217 mg/m3 OEL Malaysia: 100 ppm TWA; 434 mg/m3 TWA Netherlands: 50 ppm MAC; 215 mg/m3 MAC Russia: 50 mg/m3 TWA Spain: 100 ppm VLA-ED; 441 mg/m3 VLA-ED Spain: 200 ppm VLA-EC; 884 mg/m3 VLA-EC CAS# 106-42-3: United Kingdom, WEL - TWA: 50 ppm TWA; 220 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 441 mg/m3 STEL United States OSHA: 100 ppm TWA; 435 mg/m3 TWA (listed under Xyl (o-, m-, p- isomers)).
Belgium - TWA: 50 ppm VLE; 221 mg/m3 VLE Belgium - STEL: 150 ppm VLE; 442 mg/m3 VLE France - VME: (listed as xylenes (o-, m-, p- isomers)): 100 ppm V 435 mg/m3 VME France - VLE: (listed as xylenes (o-, m-, p- isomers)): 150 ppm V 650 mg/m3 VLE Germany: (listed as xylenes (o-, m-, p- isomers)): 100 ppm VME; 4 mg/m3 VME Germany: (listed as xylenes (o-, m-, p- isomers)): Skin absorber Japan: 50 ppm OEL; 217 mg/m3 OEL Malaysia: 199 ppm TWA; 434 mg/m3 TWA Netherlands: (listed as xylenes (o-, m-, p- isomers)): 50 ppm MAC 210 mg/m3 MAC Russia: (listed as xylenes (o-, m-, p- isomers)): 50 mg/m3 TWA Spain: 50 ppm VLA-ED; 221 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 442 mg/m3 VLA-EC CAS# 108-38-3: United Kingdom, WEL - TWA: 50 ppm TWA; 220 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 441 mg/m3 STEL United States OSHA: 100 ppm TWA; 435 mg/m3 TWA (listed under Xyl (o-, m-, p- isomers)).
Belgium - TWA: 50 ppm VLE; 221 mg/m3 VLE Belgium - STEL: 150 ppm VLE; 442 mg/m3 VLE France - VME: (listed as xylenes (o-, m-, p- isomers)): 100 ppm V 435 mg/m3 VME France - VLE: (listed as xylenes (o-, m-, p- isomers)): 150 ppm V 650 mg/m3 VLE Germany: (listed as xylenes (o-, m-, p- isomers)): 100 ppm VME; 4 mg/m3 VME Germany: (listed as xylenes (o-, m-, p- isomers)): Skin absorber Japan: 50 ppm OEL; 217 mg/m3 OEL Malaysia: 199 ppm TWA; 434 mg/m3 TWA Netherlands: (listed as xylenes (o-, m-, p- isomers)): 50 ppm MAC 210 mg/m3 MAC Russia: (listed as xylenes (o-, m-, p- isomers)): 50 mg/m3 TWA Spain: 50 ppm VLA-ED; 221 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 442 mg/m3 VLA-EC CAS# 1330-20-7: United Kingdom, WEL - TWA: 50 ppm TWA; 220 mg/m3 TWA United Kingdom, WEL - STEL: 100 ppm STEL; 441 mg/m3 STEL United States OSHA: 100 ppm TWA; 435 mg/m3 TWA Belgium - TWA: 50 ppm VLE; 221 mg/m3 VLE Belgium - STEL: 150 ppm VLE; 442 mg/m3 VLE France - VME: 100 ppm VME; 435 mg/m3 VME France - VLE: 150 ppm VLE; 650 mg/m3 VLE Germany: 100 ppm TWA; 440 mg/m3 TWA Germany: Skin absorber Japan: 50 ppm OEL; 217 mg/m3 OEL Malaysia: 199 ppm TWA; 434 mg/m3 TWA Netherlands: 50 ppm MAC; 210 mg/m3 MAC Russia: 50 mg/m3 TWA Spain: 50 ppm VLA-ED; 221 mg/m3 VLA-ED Spain: 100 ppm VLA-EC; 442 mg/m3 VLA-EC CAS# 7440-38-2: United Kingdom, WEL - TWA: 0.1 mg/m3 TWA United Kingdom, WEL - STEL: 0.3 mg/m3 STEL United States OSHA: 0.5 mg/m3 TWA Belgium - TWA: 0.01 mg/m3 VLE Japan: 3 g/m3 OEL (reference value) Malaysia: 0.01 mg/m3 TWA Netherlands: 0.050 mg/m3 MAC Spain: 0.1 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Liquid
Color: light, oily
Odor: nondescriptive
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: > 269 deg F
Freezing/Melting Point: Not available.
Autoignition Temperature: 982 deg F ( 527.78 deg C)
Flash Point: 85 deg F ( 29.44 deg C)
Explosion Limits, lower: 1.1
Explosion Limits, upper: 7.0
Decomposition Temperature:
Solubility in water: Negligible.
Specific Gravity/Density: 0.6-0.9
Molecular Formula:
Molecular Weight:

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
High temperatures, ignition sources.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, acetic acid, nitric acid.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 95-47-6: ZE2450000 CAS# 100-41-4: DA0700000 CAS# 106-42-3: ZE2625000 CAS# 108-38-3: ZE2275000 CAS# 1330-20-7: ZE2100000 CAS# 7440-38-2: CG0525000 LD50/LC50:
CAS# 95-47-6: Inhalation, mouse: LC50 = 4595 ppm/6H; Oral, rat: LD50 = 3567 mg/kg.
CAS# 100-41-4: Draize test, rabbit, eye: 500 mg Severe; Inhalation, mouse: LC50 = 35500 mg/m3/2H; Inhalation, rat: LC50 = 55000 mg/m3/2H; Oral, rat: LD50 = 3500 mg/kg; Oral, rat: LD50 = 3500 mg/kg; Skin, rabbit: LD50 = 17800 uL/kg.
CAS# 106-42-3: Inhalation, rat: LC50 = 4550 ppm/4H; Oral, rat: LD50 = 3910 mg/kg.
CAS# 108-38-3: Draize test, rabbit, eye: 5 mg/24H Severe; Draize test, rabbit, skin: 20 mg/24H Moderate; Inhalation, mouse: LC50 = 5267 ppm/6H; Oral, rat: LD50 = 4988 mg/kg; Skin, rabbit: LD50 = 14100 uL/kg.
CAS# 1330-20-7: Draize test, rabbit, eye: 87 mg Mild; Draize test, rabbit, eye: 5 mg/24H Severe; Draize test, rabbit, skin: 100% Moderate; Draize test, rabbit, skin: 500 mg/24H Moderate; Inhalation, rat: LC50 = 5000 ppm/4H; Oral, mouse: LD50 = 2119 mg/kg; Oral, rat: LD50 = 4300 mg/kg; Skin, rabbit: LD50 = >1700 mg/kg.
CAS# 7440-38-2: Oral, mouse: LD50 = 145 mg/kg; Oral, mouse: LD50 = 144 mg/kg; Oral, rat: LD50 = 763 mg/kg; Oral, rat: LD50 = 763 mg/kg.
Carcinogenicity:
o-Xylene - Not listed by ACGIH, IARC, or NTP.
Ethylbenzene - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 6/11/04 IARC: Group 2B carcinogen p-Xylene - Not listed by ACGIH, IARC, or NTP.
m-Xylene - Not listed by ACGIH, IARC, or NTP.
Xylenes (o-, m-, p- isomers) - Not listed by ACGIH, IARC, or NTP.
Arsenic - ACGIH: A1 - Confirmed Human Carcinogen IARC: Group 1 carcinogen Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
  Ecotoxicity:
Fish: Rainbow trout: LC50 = 13.5 mg/L; 96 Hr; UnspecifiedFish: Goldfish: LD50 = 13 mg/L; 24 Hr; UnspecifiedFish: Fathead Minnow: LC50 = 46 mg/L; 1 Hr; Static bioassayAcute and long-term toxicity to fish and invertebrates: LD50 for goldfish is 13 mg/L/24 Hr.
Cas#1330-20-7: LC50(96Hr.) rainbow trout = 8.05 mg/L, Static condition; LC50(96Hr.) fathead minnow = 16.1 mg/L, flow-through conditions; LC50(96Hr.) bluegill = 16.1 mg/L, flow-through; EC50 (48 Hr.) water flea = 3.82 mg/L, flow-through conditions; EC50(24 Hr.) photobacterium phosphoreum = 0.0084 mg/L, Microtox test.

Section 13 - DISPOSAL CONSIDERATIONS
  Products which are considered hazardous for supply are classified as Special Waste and the disposal of such chemicals is covered by regulations which may vary according to location. Contact a specialist disposal company or the local waste regulator for advice. Empty containers must be decontaminated before returning for recycling.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: XYLENE
Hazard Class: 3
UN Number: 1307
Packing Group: III
IMO
Shipping Name: XYLENE
Hazard Class: 3
UN Number: 1307
Packing Group: III
RID/ADR
Shipping Name: XYLENE
Hazard Class: 3
UN Number: 1307
Packing group:
USA RQ: CAS# 95-47-6: 1000 lb final RQ (Listed under Xylene, mixed); 454 kg fina
USA RQ: CAS# 100-41-4: 1000 lb final RQ; 454 kg final RQ
USA RQ: CAS# 106-42-3: 100 lb final RQ (Listed under Xylene, mixed); 45.4 kg fin
USA RQ: CAS# 108-38-3: 1000 lb final RQ (Listed under Xylene, mixed); 454 kg fin
USA RQ: CAS# 1330-20-7: 100 lb final RQ; 45.4 kg final RQ
USA RQ: CAS# 7440-38-2: 1 lb final RQ (no reporting of releases of this hazardou

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 10 Flammable.
R 20/21 Harmful by inhalation and in contact with
skin.
R 38 Irritating to skin.
Safety Phrases:
S 25 Avoid contact with eyes.
WGK (Water Danger/Protection)
CAS# 95-47-6: 2
CAS# 100-41-4: 1
CAS# 106-42-3: 2
CAS# 108-38-3: No information available.
CAS# 1330-20-7: 2
CAS# 7440-38-2: No information available.
Canada
CAS# 95-47-6 is listed on Canada's DSL List.
CAS# 100-41-4 is listed on Canada's DSL List.
CAS# 106-42-3 is listed on Canada's DSL List.
CAS# 108-38-3 is listed on Canada's DSL List.
CAS# 1330-20-7 is listed on Canada's DSL List.
CAS# 7440-38-2 is listed on Canada's DSL List.
CAS# 95-47-6 is listed on Canada's Ingredient Disclosure List.
CAS# 100-41-4 is listed on Canada's Ingredient Disclosure List.
CAS# 106-42-3 is listed on Canada's Ingredient Disclosure List.
CAS# 108-38-3 is listed on Canada's Ingredient Disclosure List.
CAS# 1330-20-7 is not listed on Canada's Ingredient Disclosure List.
CAS# 7440-38-2 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 95-47-6 is listed on the TSCA inventory.
CAS# 100-41-4 is listed on the TSCA inventory.
CAS# 106-42-3 is listed on the TSCA inventory.
CAS# 108-38-3 is listed on the TSCA inventory.
CAS# 1330-20-7 is listed on the TSCA inventory.
CAS# 7440-38-2 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

Spectrum

NMR Spectrum 1H NMR : Predict
expand collapse

Related Compound Information