5750-76-5 structure, C4HCl3N2

2,4,5-Trichloropyrimidine

CAS No.

5750-76-5

Formula:

C4HCl3N2

Basic Info

2,4,5-Trichloropyrimidine is used in the synthesis of potent and selective anaplastic lymphoma kinase (ALK-5) inhibitors, used as an anti-tumor treatment. Also used in the synthesis of EGFR inhibitors.

Formula
C4HCl3N2
Molecular Weight
183.423
Exact Mass
181.921
LogP
2.4368
PSA
25.78
Synonyms

2,5,6-TRICHLOROPYRIMIDINE

2,4,5-Trichlor-pyrimidin

2,4,5-trichloro-pyrimidine

trichloropyrimidine

5-chloro-2,4-dichloro-pyrimidine

2,3-DIHYDRO-1H-INDEN-5-YL HYDROSULFIDE

expand collapse

Properties

Appearance & Physical State
Colorless to pale yellow liquid
Density
1.6001
Boiling Point
258.5ºC at 760 mmHg
Flash Point
>110ºC
Refractive Index
1.574

Safety Info

Safety Statements
S26-S36
WGK Germany
3
Risk Statements
R36/37/38
HS Code
2933599090
RIDADR
UN1760
Hazard Class
8
Packing Group
III
Caution Statement
P261; P305 + P351 + P338
Hazard Codes
Hazard Declaration
Caution Statement

Synthesis Route

1.Synthesis Route

Precursor

Related Compound Information