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Asphalt
CAS No.8052-42-4
Formula:
Synonyms
Bitumens, extracts of steam-refined and air-refined, steam-refined, cracking-residue and air-refined bitumens
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TUMORIGENIC DATA
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Type of Test
TDLo - Lowest published toxic dose
Exposure Route
Intramuscular
Species Observed
Rodent - rat
Dose/Duration
5400 mg/kg/24W-I
Toxic Effects
Tumorigenic--neoplastic by RTECS criteria<br>Tumorigenic--facilitates action of known carcinogen
Reference
Archives of Pathology. (Chicago, IL) V.5(3)-50(3), 1928-50; V.70-99, 1960-75. For publisher information, see APLMAS. Volume(issue)/page/year: 70,372,1960
TUMORIGENIC DATA
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Type of Test
TDLo - Lowest published toxic dose
Exposure Route
Administration onto the skin
Species Observed
Rodent - mouse
Dose/Duration
130 gm/kg/81W-I
Toxic Effects
Tumorigenic--Carcinogenic by RTECS criteria<br>Lungs, Thorax, or Respiration--tumors<br>Skin and Appendages--tumors
Reference
Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 33(4-6),180,1968
TUMORIGENIC DATA
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collapse
Type of Test
TDLo - Lowest published toxic dose
Exposure Route
Intramuscular
Species Observed
Rodent - mouse
Dose/Duration
12 gm/kg/12W-I
Toxic Effects
Tumorigenic--neoplastic by RTECS criteria<br>Tumorigenic--tumors at site of application
Reference
Archives of Pathology. (Chicago, IL) V.5(3)-50(3), 1928-50; V.70-99, 1960-75. For publisher information, see APLMAS. Volume(issue)/page/year: 70,372,1960
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