107-07-3 structure, C2H5ClO

2-chloroethanol

CAS No.

107-07-3

Formula:

C2H5ClO

Basic Info

2-Chloroethanol is an chemical compound with the formula HOCH2CH2Cl and the simplest chlorohydrin. This colorless liquid has a pleasant ether-like odor. It is miscible with water. The molecule is bifunctional, consisting of both an alkyl chloride and an alcohol functional groups.

Formula
C2H5ClO
Molecular Weight
80.5135
Exact Mass
80.0029
LogP
0.2175
PSA
20.23
Synonyms

2-hydroxyethyl chloride

2-chloro-ethanol

1-chloro-2-hydroxy-ethane

Ethanol, 2-chloro-

Chloroethanol

methanol,methyl chloride

2-CHLORETHANOL

2-Cloroetanolo

2-chloro-ethano

Ethylene chlorohydrin

2-Chloraethanol

Ghlorohydrin

Z-Chloroethanol

2-chloro-1-ethanol

2-Chloroethanol

CH2ClCH2OH

2-Chloorethanol

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Properties

Appearance & Physical State
clear, colorless liquid.
Density
1.201
Boiling Point
129ºC
Melting Point
-63ºC
Flash Point
55ºC
Refractive Index
1.4405-1.4425
Water Solubility
MISCIBLE
Stability
Stable. Incompatible with oxidizing agents.
Storage Condition
2-8ºC
Vapor Density
2.78 (vs air)
Vapor Pressure
5 mm Hg ( 20 °C)

Safety Info

RTECS
KK0875000
Safety Statements
S28-S45-S7/9
WGK Germany
3
Risk Statements
R26/27/28
HS Code
29333999
RIDADR
UN 1135
Hazard Class
6.1
Packing Group
I
Hazard Codes

MSDS

SDS 1.0
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SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloroethanol

1.2 Other means of identification

Product number -
Other names CH2ClCH2OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Intermediates
Uses advised against no data available

1.4 Supplier's details

Company MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road,
Xuhui District, Shanghai, China
Telephone +86(21)64956998
Fax +86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-400-6021-666
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 2

Acute toxicity - Dermal, Category 1

Acute toxicity - Inhalation, Category 2

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Danger

Hazard statement(s)

H300 Fatal if swallowed

H310 Fatal in contact with skin

H330 Fatal if inhaled

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P262 Do not get in eyes, on skin, or on clothing.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P284 [In case of inadequate ventilation] wear respiratory protection.

Response

P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/…

P321 Specific treatment (see ... on this label).

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P310 Immediately call a POISON CENTER/doctor/…

P361+P364 Take off immediately all contaminated clothing and wash it before reuse.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P320 Specific treatment is urgent (see ... on this label).

Storage

P405 Store locked up.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
2-chloroethanol 2-chloroethanol 107-07-3 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.

In case of skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

Very toxic; probable oral lethal dose in humans is 50-500 mg/kg or between 1 teaspoon and 1 ounce for a 70 kg (150 lb.) person. Poisoning causes liver and kidney degeneration and irritates mucous membranes; it may be cumulative. Several fatal cases with brain edema and lung edema have been reported from industrial exposure by inhalation and skin contact. It is more toxic by skin contact than orally. (EPA, 1998)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Minimum/Potential Fatal Human Dose

4= VERY TOXIC: PROBABLE ORAL LETHAL DOSE (HUMAN) 50-500 MG/KG, BETWEEN 1 TEASPOON & 1 OUNCE FOR 70 KG PERSON (150 LB).

Absorption, Distribution and Excretion

... MAY BE ABSORBED THROUGH THE SKIN.

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Water, alcohol foam, dry chemical, or carbon dioxide.

5.2 Specific hazards arising from the chemical

Its decomposition products will react with water or steam to produce toxic and corrosive fumes of phosgene and hydrogen chloride. Vapors are heavier than air and may flash back to a source of ignition. (EPA, 1998)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Personal protection: complete protective clothing including self-contained breathing apparatus. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

6.3 Methods and materials for containment and cleaning up

1. Remove all ignition sources. 2. Ventilate area of spill or leak. 3. For small quantities, absorb on paper towels. Evaporate in a safe place (such as a fume hood). Allow sufficient time for evaporating vapors to completely clear the hood ductwork. Burn the paper in a suitable location away from combustible materials. Large quantities can be collected and atomized in a suitable combustion chamber equipped with an appropriate effluent gas cleaning device. Ethylene chlorohydrin should not be allowed to enter a confined space, such as a sewer, because of the possibility of an explosion.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Fireproof. Separated from strong bases, oxidants and food and feedstuffs. Dry. Well closed.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

Recommended Exposure Limit: Ceiling value: 1 ppm (3 mg/cu m), skin.

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state clear, colorless liquid.
Colour COLORLESS GLYCERINE-LIKE LIQ
Odour FAINT ETHEREAL ODOR
Melting point/ freezing point -63ºC
Boiling point or initial boiling point and boiling range 129ºC
Flammability Class IIIA Combustible Liquid: Fl.P. at or above 60°C and below 93.33°C.Flammable. Gives off irritating or toxic fumes (or gases) in a fire.
Lower and upper explosion limit / flammability limit Lower flammable limit: 4.9% by volume; Upper flammable limit: 15.9% by volume
Flash point 55ºC
Auto-ignition temperature 425°C (USCG, 1999)
Decomposition temperature no data available
pH no data available
Kinematic viscosity 0.0343 POISE @ 20 DEG C
Solubility In water:MISCIBLE
Partition coefficient n-octanol/water (log value) log Kow = -0.06
Vapour pressure 5 mm Hg ( 20 °C)
Density and/or relative density 1.201
Relative vapour density 2.78 (vs air)
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

IT EVAPORATES READILY AT ROOM TEMPERATURE

10.3 Possibility of hazardous reactions

MODERATE, WHEN EXPOSED TO HEAT, FLAME OR OXIDIZERS.Mixing ethylene chlorohydrin in equal molar portions with any of the following substances in a closed container caused the temperature and pressure to increase: chlorosulfonic acid, ethylene diamine, and sodium hydroxide, [NFPA 1991]. Ethylenediamine reacts violently with ethylene chlorohydrin. (Lewis, R.J., Sr. 1992. Sax's Dangerous Properties of Industrial Materials, 8th Edition. New York: Van Nostrand Reinhold. pp. 1554.).

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

... WILL REACT WITH WATER OR STEAM TO PRODUCE TOXIC & CORROSIVE FUMES ... .

10.6 Hazardous decomposition products

... WHEN HEATED TO DECOMPOSITION, IT EMITS HIGHLY TOXIC FUMES OF PHOSGENE ... .

11.Toxicological information

Acute toxicity

  • Oral: LD50 Rat oral 58 mg/kg
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

A4; Not classifiable as a human carcinogen.

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: LC50 Pimephales promelas (fathead minnow) 83.7 mg/l/96 hr (95% confidence limit 75.0-93.4 mg/l), flow-through bioassay with measured concentrations, 24.0°C, dissolved oxygen 7.1 mg/l, hardness 52.3 mg/l calcium carbonate, alkalinity 44.2 mg/l calcium carbonate, and pH 7.22.
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

2-Chloroethanol is readily biodegradable in screening tests and biological treatment simulations using sewage and activated sludge inocula(1-6). Various investigators have obtained the following results in percent of theoretical BOD in screening tests using sewage inocula: 57% in 20 days(1); 50% in 10 days(2); and 87% in 10 days(3). The results of these screening tests indicate that acclimation is important in the biodegradation process.

12.3 Bioaccumulative potential

Using the log octanol/water partition coefficient for 2-chloroethanol, 0.03(1), one can estimate a BCF of 0.62 using a recommended regression equation(2,SRC). Therefore, 2-chloroethanol would not be expected to bioconcentrate in aquatic organisms.

12.4 Mobility in soil

The Koc for 2-chloroethanol estimated from molecular structure is 1.33(1). According to a suggested classification scheme, a Koc of this magnitude indicates that 2-chloroethanol will exhibit very high mobility in soil(2).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN1135 IMDG: UN1135 IATA: UN1135

14.2 UN Proper Shipping Name

ADR/RID: ETHYLENE CHLOROHYDRIN
IMDG: ETHYLENE CHLOROHYDRIN
IATA: ETHYLENE CHLOROHYDRIN

14.3 Transport hazard class(es)

ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1

14.4 Packing group, if applicable

ADR/RID: I IMDG: I IATA: I

14.5 Environmental hazards

ADR/RID: no IMDG: no IATA: no

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
2-chloroethanol 2-chloroethanol 107-07-3 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 19, 2017
Revision Date Aug 19, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
MSDS
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Name: 2-Chloroethanol 99% Material Safety Data Sheet
Synonym: 2-Chloroethyl Alcohol; Glycol Chlorohydrin
CAS: 107-07-3
Section 1 - Chemical Product   MSDS Name:2-Chloroethanol 99% Material Safety Data Sheet
Synonym:2-Chloroethyl Alcohol; Glycol Chlorohydrin

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
107-07-3 2-Chloroethanol 99 203-459-7
Hazard Symbols: T+
Risk Phrases: 26/27/28

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Very toxic by inhalation, in contact with skin and if swallowed.Moisture sensitive.
Potential Health Effects
Eye:
Causes severe eye irritation. May cause chemical conjunctivitis and corneal damage.
Skin:
Causes skin irritation. May be fatal if absorbed through the skin.
May cause irritation and dermatitis. May cause cyanosis of the extremities.
Ingestion:
Harmful if swallowed. May cause central nervous system depression, kidney damage, and liver damage. Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. Causes gastrointestinal irritation with nausea, vomiting and diarrhea.
Human fatalities have been reported from acute poisoning.
Inhalation:
Harmful if inhaled. Causes severe irritation of upper respiratory tract with coughing, burns, breathing difficulty, and possible coma.
May cause lung damage. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. Inhalation at high concentrations may cause CNS depression and asphixiation. May cause burning sensation in the chest.
Chronic:
May cause liver and kidney damage. May cause fetal effects. Effects may be delayed.

Section 4 - FIRST AID MEASURES
  Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable liquid and vapor. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use foam, dry chemical, or carbon dioxide. Water may be ineffective. DO NOT USE WATER! Do NOT get water inside containers. Do NOT use straight streams of water.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Use a spark-proof tool.
Provide ventilation. Do not get water inside containers. A vapor suppressing foam may be used to reduce vapors.

Section 7 - HANDLING and STORAGE
  Handling:
Wash hands before eating. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not allow contact with water. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep from contact with moist air and steam.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Store protected from moisture.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits CAS# 107-07-3: United Kingdom, WEL - STEL: 1 ppm STEL; 3.4 mg/m3 STEL United States OSHA: 5 ppm TWA; 16 mg/m3 TWA Belgium - STEL: 1 ppm VLE; 3.3 mg/m3 VLE France - VLE: 1 ppm VLE; 3 mg/m3 VLE Germany: 1 ppm TWA; 3.3 mg/m3 TWA Germany: Skin absorber Malaysia: 1 ppm Ceiling; 3.3 mg/m3 Ceiling Russia: 0.5 mg/m3 TWA Spain: 1 ppm VLA-EC; 3.3 mg/m3 VLA-EC Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Liquid
Color: clear, colorless
Odor: Faint, ethereal odor.
pH: Not available.
Vapor Pressure: 10 mm Hg @ 30 C
Viscosity: Not available.
Boiling Point: 129 deg C
Freezing/Melting Point: -89 deg C
Autoignition Temperature: 797 deg F ( 425.00 deg C)
Flash Point: 140 deg F ( 60.00 deg C)
Explosion Limits, lower: 4.9
Explosion Limits, upper: 15.9
Decomposition Temperature: Not available.
Solubility in water: Miscible with water.
Specific Gravity/Density: 1.20
Molecular Formula: C2H5ClO
Molecular Weight: 80.4874

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
High temperatures, mechanical shock, incompatible materials, ignition sources, moisture, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Moisture, strong oxidizing agents, strong acids, strong bases.
Hazardous Decomposition Products:
Hydrogen chloride, chlorine, phosgene, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 107-07-3: KK0875000 LD50/LC50:
CAS# 107-07-3: Dermal, guinea pig: LD50 = 20 mg/kg; Draize test, rabbit, eye: 2 mg Severe; Draize test, rabbit, eye: 33 mg Moderate; Draize test, rabbit, eye: 9 mg/6H Moderate; Draize test, rabbit, skin: 200 mg/2H Mild; Inhalation, mouse: LC50 = 385 mg/m3; Inhalation, mouse: LC50 = 385 mg/m3; Inhalation, rat: LC50 = 290 mg/m3; Inhalation, rat: LC50 = 290 mg/m3; Oral, mouse: LD50 = 81 mg/kg; Oral, mouse: LD50 = 91 mg/kg; Oral, rabbit: LD50 = 100 mg/kg; Oral, rat: LD50 = 71 mg/kg; Oral, rat: LD50 = 71 mg/kg; Skin, rabbit: LD50 = 67 mg/kg; Skin, rabbit: LD50 = 700 mg/kg; Skin, rat: LD50 = 293 mg/kg.
Carcinogenicity:
2-Chloroethanol - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
  Other For more information, see "HANDBOOK OF ENVIRONMENTAL FATE AND EXPOSURE DATA."

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: ETHYLENE CHLOROHYDRIN
Hazard Class: 6.1 (3)
UN Number: 1135
Packing Group:
IMO
Shipping Name: ETHYLENE CHLOROHYDRIN
Hazard Class: 6.1 (3.3)
UN Number: 1135
Packing Group: I
RID/ADR
Shipping Name: ETHYLENE CHLOROHYDRIN
Hazard Class: 6.1
UN Number: 1135
Packing group: I

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+
Risk Phrases:
R 26/27/28 Very toxic by inhalation, in contact with
skin and if swallowed.
Safety Phrases:
S 7/9 Keep container tightly closed and in a
well-ventilated place.
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 28 After contact with skin, wash immediately
with...
S 28A After contact with skin, wash immediately with
plenty of water.
S 33 Take precautionary measures against static
discharges.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 107-07-3: 3
Canada
CAS# 107-07-3 is listed on Canada's DSL List.
CAS# 107-07-3 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 107-07-3 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

Spectrum

NMR Spectrum 1H NMR : 90 MHz in CDCl3
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IR Spectrum IR : liquid film
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Mass Spectrum Mass spectrum (electron ionization)
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Raman Spectrum Raman : 4880 A,200 M,liquid
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Analysis Methods

Kovats' RI, non-polar column, isothermal
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Column Shape
Packed
Active Phase(℃)
Apiezon L
Retention index
633.
Temperature Control
120.
Method
isothermal
Comments
Celite 545
Reference
Bogoslovsky, Yu.N.Anvaer, B.I.Vigdergauz, M.S.Chromatographic constants in gas chromatography (in Russian)Standards Publ. House, Moscow, 1978, 192.
Kovats' RI, non-polar column, isothermal
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Column Shape
Packed
Active Phase(℃)
Apiezon L
Retention index
635.
Temperature Control
160.
Method
isothermal
Comments
Celite 545
Reference
Bogoslovsky, Yu.N.Anvaer, B.I.Vigdergauz, M.S.Chromatographic constants in gas chromatography (in Russian)Standards Publ. House, Moscow, 1978, 192.
Kovats' RI, non-polar column, isothermal
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Column Shape
Packed
Active Phase(℃)
Silicon High Vacuum Grease (obsolete)
Retention index
680.
Temperature Control
170.
Method
isothermal
Comments
H2, Celite
Reference
Janák, J.Jonas, J.Kratochvíl, M.Identification of some acetals of the tetrahydrofurane sereis by gas chromatography with the aid of the Kováts indicesCollect. Czech. Chem. Commun.1965, 30, 1, 265-276.
Van Den Dool and Kratz RI, non-polar column, temperature ramp
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Column Shape
Capillary
Active Phase(℃)
SE-30
Retention index
614.
Temperature Control
Method
temperature ramp
Comments
N2, 10. K/min; Column length: 25. m; Column diameter: 0.33 mm; T<sub>start</sub>: 100. C
Reference
Korhonen, I.O.O.Gas-liquid chromatographic analyses. XXXIX. ω-Chloroethanols on low-polarity (SE-30) and polar (OV-351) capillary columnsJ. Chromatogr.1985, 324, 181-191.
Van Den Dool and Kratz RI, non-polar column, temperature ramp
expand collapse
Column Shape
Capillary
Active Phase(℃)
SE-30
Retention index
633.
Temperature Control
Method
temperature ramp
Comments
N2, 2. K/min; Column length: 25. m; Column diameter: 0.33 mm; T<sub>start</sub>: 100. C
Reference
Korhonen, I.O.O.Gas-liquid chromatographic analyses. XXXIX. ω-Chloroethanols on low-polarity (SE-30) and polar (OV-351) capillary columnsJ. Chromatogr.1985, 324, 181-191.

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