696-07-1 structure, C4H3IN2O2

5-iodouracil

CAS No.

696-07-1

Formula:

C4H3IN2O2

Basic Info

5-Iodouracil is a halogenated pyrimidine that can be used in nucleoprotein photo-crosslinking via RNA substitution. 5-Iodouracil is used in thymidine phosphorylase targeted imaging and therapy. Studies show that DNA N-glycosylase MED1 exhibited higher preference for 5-Iodouracil and halogenated bases over non-halogenated ones.

Formula
C4H3IN2O2
Molecular Weight
237.983
Exact Mass
237.924
LogP
0.4924
PSA
66.24
Synonyms

5-iodopyriMidine-2.4-diol

5-iodo uracil

4-iodouracil

5-Iodouracil

5-iodo-uraci

5-iodo-2,4-dioxopyrimidine

5-iodine uracil

5-iodopyrimidine-2,4(1H,3H)-dione

2,4(1H,3H)-Pyrimidinedione, 5-iodo-

5IU

5-IODOURACIL extrapure

expand collapse

Properties

Appearance & Physical State
silvery white or off white crystalline powder
Density
2.39 g/cm3
Boiling Point
401ºC
Melting Point
270-274ºC
Refractive Index
1.705
Water Solubility
SOLUBLE IN COLD WATER
Stability
Stable under normal temperatures and pressures.
Storage Condition
0-6ºC

Safety Info

RTECS
YR0525000
Safety Statements
S53-S22-S26-S36/37/39-S45
WGK Germany
3
Risk Statements
R46; R20/21/22; R36/37/38
HS Code
2933599090
RIDADR
UN 2811
Caution Statement
P261; P280; P305 + P351 + P338
Hazard Codes

Synthesis Route

Related Compound Information