CAS No. 67-72-1

Formula: C2Cl6
Basic Info

Hexachloroethane, also known as perchloroethane (PCA), C2Cl6, is a white crystalline solid at room temperature with a camphor-like odor. It has been used by the military in smoke compositions, such as base-eject smoke munitions (smoke grenades).

Molecular Weight
Exact Mass

Ethane, hexachloro-


expand collapse

Appearance & Physical State
white crystalline powder
Boiling Point
Melting Point
Flash Point
Refractive Index
Water Solubility
0.05 g/L (22 ºC)
Stable. Non-combustible. May react with hot metals, strong oxidizing agents.
Storage Condition
Vapor Density
8.16 (vs air)
Vapor Pressure
0.4 mm Hg ( 20 °C)
Safety Info
Safety Statements
WGK Germany
Risk Statements
R36/37/38; R40; R51/53
HS Code
UN 9037
Hazard Class
Packing Group
Hazard Codes
SDS 1.0
expand collapse
Download/Modify | Technical supported by XiXisys.com. For US version, EU version (23 languages) and more, please refer to xixisys.com/en/sds/search


According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name hexachloroethane

1.2 Other means of identification

Product number -
Other names Ethane, hexachloro-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Volatile organic compounds
Uses advised against no data available

1.4 Supplier's details

Company MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road,
Xuhui District, Shanghai, China
Telephone +86(21)64956998
Fax +86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-400-6021-666
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity – single exposure, Category 3

Carcinogenicity, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

2.2 GHS label elements, including precautionary statements

Signal word


Hazard statement(s)

H315 Causes skin irritation

H319 Causes serious eye irritation

H335 May cause respiratory irritation

H351 Suspected of causing cancer

H410 Very toxic to aquatic life with long lasting effects

Precautionary statement(s)

P264 Wash ... thoroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and understood.

P273 Avoid release to the environment.


P302+P352 IF ON SKIN: Wash with plenty of water/...

P321 Specific treatment (see ... on this label).

P332+P313 If skin irritation occurs: Get medical advice/attention.

P362+P364 Take off contaminated clothing and wash it before reuse.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P337+P313 If eye irritation persists: Get medical advice/attention.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P312 Call a POISON CENTER/doctor/…if you feel unwell.

P308+P313 IF exposed or concerned: Get medical advice/ attention.

P391 Collect spillage.


P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.


P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification


3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
hexachloroethane hexachloroethane 67-72-1 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest.

In case of skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap.

In case of eye contact

Rinse with plenty of water for several minutes (remove contact lenses if easily possible). Refer for medical attention.

If swallowed

Rinse mouth. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

Compound is a powerful narcotic and liver poison; may also cause changes in blood composition and neurological disturbances. Repeated exposure by inhalation can be fatal. Ingestion causes vomiting, diarrhea, severe mucosal injury, liver necrosis, cyanosis, unconsciousness, loss of reflexes, and death. Contact with eyes causes irritation and lachrymation. Can be absorbed through the skin and may produce severe skin lesions. (USCG, 1999)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Military Smoke Agents/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.

5.2 Specific hazards arising from the chemical

Special Hazards of Combustion Products: Irritating hydrogen chloride vapor may form in fire. (USCG, 1999)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. Carefully collect remainder. Then store and dispose of according to local regulations.

6.3 Methods and materials for containment and cleaning up

1. Ventilate area of spill; 2. Collect spilled material in the most convenient and safe manner for reclamation or for disposal. ... Liquid containing hexachloroethane should be absorbed in vermiculite, dry sand, earth or a similar material.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Separated from strong oxidants, alkali metals and food and feedstuffs. See Chemical Dangers. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing....Hexachloroethane must be stored to avoid contact with hot iron, zinc, aluminum, and alkalis, since violent reactions occur. Store in tightly closed containers in a cool, well-ventilated area away from heat.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 1 ppm (10 mg/cu m), skin.

NIOSH considers hexachloroethane to be a potential occupational carcinogen.

NIOSH considers ethylene dichloride; hexachloroethane; 1,1,2,2-tetrachloroethane; and 1,1,2-trichloroethane; to be potential occupational carcinogens. Additionally, NIOSH recommends that the other five chloroethane compounds: 1,1-dichloroethane; ethyl chloride; methyl chloroform; pentachloroethane; and 1,1,1,2-tetrachloroethane be treated in the workplace with caution because of their structural similarity to the four chloroethanes shown to be carcinogenic in animals.

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state white crystalline powder
Colour Colorless crystals
Odour Camphor-like odor
Melting point/ freezing point 133°C(dec.)(lit.)
Boiling point or initial boiling point and boiling range 155°C/15mmHg(lit.)
Flammability Noncombustible SolidNot combustible. Gives off irritating or toxic fumes (or gases) in a fire.
Lower and upper explosion limit / flammability limit no data available
Flash point 152°C(lit.)
Auto-ignition temperature no data available
Decomposition temperature no data available
pH no data available
Kinematic viscosity no data available
Solubility In water:0.05 g/L (22 ºC)
Partition coefficient n-octanol/water (log value) log Kow = 4.14
Vapour pressure 0.4 mm Hg ( 20 °C)
Density and/or relative density 2.091
Relative vapour density 8.16 (vs air)
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

Not flammable by standard tests in air.HEXACHLOROETHANE can react with hot iron, zinc and aluminum. Dehalogenation of this material by reaction with alkalis and metals will produce unstable chloroacetylenes. It can also react with strong oxidizing agents. .

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Hexachloroethane was among a number of chemicals studied for vigorous reactions with zinc, cadmium, or mercury.

10.6 Hazardous decomposition products

When heated to decomposition it emits toxic fumes of /hydrogen chloride/ and phosgene.

11.Toxicological information

Acute toxicity

  • Oral: LD50 Rat female oral, diluent: corn oil, 4460 mg/kg /From table/
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available


NTP: Reasonably anticipated to be a human carcinogen

Reproductive toxicity

No information is available on the reproductive or developmental effects of hexachloroethane in humans. At the highest concentrations, rats exposed to hexachloroethane by inhalation exhibited maternal toxicity, but there was no evidence of fetotoxicity or teratogenicity (birth defects). In rats exposed to high doses of hexachloroethane via gavage, maternal toxicity, a reduced gestation index, a reduction in the number of fetuses per female, and increased fetal resorption rates were observed.

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill, 0.7 g); Conditions: freshwater, flow through, 17.3°C, pH 7.1-7.8), hardness 44.4 mg/L CaCO3 (40.7-46.6 mg/L CaCO3), alkalinity 45.4 mg/L CaCO3 (42.3-57.0 mg/L CaCO3), dissolved oxygen 6.7 mg/L (4.0-8.4 mg/L); Concentration: 1820 ug/L for 24 hr
  • Toxicity to daphnia and other aquatic invertebrates: LC50 Daphnia magna 2.9 mg/L/48 hr /Conditions of bioassay not specified/.
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: Hexachloroethane at 100 mg/L achieved 0% of its theoretical BOD using an activated sludge inoculum at 30 mg/L over a 2 week incubation period and the Japanese MITI test(1). The biodegradation half-life of hexachloroethane in a non-adapted aerobic sandy soil was reported as 25-48 days(2).

12.3 Bioaccumulative potential

Bioconcentration factors of 139, 708, and 510 were measured for hexachloroethane in bluegill sunfish(1), fathead minnows(2) and rainbow trout(3), respectively. BCF values of 1.4-8.5 and 1.0-6.8 have been measured for hexachloroethane at 5 ug/L and 0.5 ug/L in carp(4). According to a classification scheme(5), BCF values of zero to 30 indicate the potential for bioconcentration in aquatic organisms are low and from 100 to 1,000 are high(SRC).

12.4 Mobility in soil

Measured Koc values ranging from 1,380 to 2,360 have been reported for hexachloroethane(1,2). According to a classification scheme(3), this range of Koc values suggests that hexachloroethane is expected to have low to slight mobility in soil.

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods


The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN3077 IMDG: UN3077 IATA: UN3077

14.2 UN Proper Shipping Name


14.3 Transport hazard class(es)


14.4 Packing group, if applicable


14.5 Environmental hazards

ADR/RID: yes IMDG: yes IATA: yes

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
hexachloroethane hexachloroethane 67-72-1 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Not Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 12, 2017
Revision Date Aug 12, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%


  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
expand collapse
Name: Hexachloroethane 99% Material Safety Data Sheet
Synonym: Ethane hexachloride; Ethylene hexachloride; 1,1,1,2,2,2-Hexachloroethane; Hexachloroethylene; Carbon hexachloride; Perchlorethan
CAS: 67-72-1
Section 1 - Chemical Product   MSDS Name:Hexachloroethane 99% Material Safety Data Sheet
Synonym:Ethane hexachloride; Ethylene hexachloride; 1,1,1,2,2,2-Hexachloroethane; Hexachloroethylene; Carbon hexachloride; Perchlorethan

CAS# Chemical Name content EINECS#
67-72-1 Hexachloroethane 99 200-666-4
Hazard Symbols: XN
Risk Phrases: 36/37/38 40

Irritating to eyes, respiratory system and skin. Limited evidence of a carcinogenic effect.Cancer suspect agent.
Potential Health Effects
Causes eye irritation. May result in corneal injury.
Causes skin irritation.
May cause central nervous system depression, kidney damage, and liver damage. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Causes irritation of mucous membrane. Causes upper respiratory tract irritation.
Possible cancer hazard based on tests with laboratory animals. May cause liver and kidney damage.

  Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:

  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

  General Information: Use proper personal protective equipment as indicated in Section 8.
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Do not let this chemical enter the environment.

Section 7 - HANDLING and STORAGE
Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Store in a cool, dry place. Keep container closed when not in use.

  Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits CAS# 67-72-1: United States OSHA: 1 ppm TWA; 10 mg/m3 TWA Belgium - TWA: 1 ppm VLE; 9.8 mg/m3 VLE France - VME: 1 ppm VME France - VLE: 10 ppm VLE Germany: 1 ppm TWA; 9.8 mg/m3 TWA Malaysia: 1 ppm TWA; 9.7 mg/m3 TWA Netherlands: 1 ppm MAC; 10 mg/m3 MAC Spain: 1 ppm VLA-ED; 9.8 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Wear appropriate protective gloves to prevent skin exposure.
Wear appropriate protective clothing to prevent skin exposure.
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Physical State: Crystals
Color: colorless
Odor: camphor
pH: Not available.
Vapor Pressure: 0.21 mm Hg @ 20
Viscosity: Not available.
Boiling Point: 186 deg C @ 777mm Hg (subl.)
Freezing/Melting Point: 185 deg C
Autoignition Temperature: Not available.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Insoluble.
Specific Gravity/Density: 2.091
Molecular Formula: C2Cl6
Molecular Weight: 236.74

  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Metals, strong oxidizing agents, strong bases, alkalies.
Hazardous Decomposition Products:
Phosgene, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, chloride fumes.
Hazardous Polymerization: Has not been reported.

CAS# 67-72-1: KI4025000 LD50/LC50:
CAS# 67-72-1: Oral, rat: LD50 = 4460 mg/kg; Skin, rabbit: LD50 = 32 gm/kg.
Hexachloroethane - ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to California: carcinogen, initial date 7/1/90 NTP: Suspect carcinogen IARC: Group 2B carcinogen Other:
See actual entry in RTECS for complete information.

  Other No information available.

  Dispose of in a manner consistent with federal, state, and local regulations.

Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
USA RQ: CAS# 67-72-1: 100 lb final RQ; 45.4 kg final RQ

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 40 Limited evidence of a carcinogenic effect.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 67-72-1: 3
CAS# 67-72-1 is listed on Canada's DSL List.
CAS# 67-72-1 is listed on Canada's Ingredient Disclosure List.
CAS# 67-72-1 is listed on the TSCA inventory.

NMR Spectrum 13C NMR : in CDCl3
expand collapse
IR Spectrum IR : KBr disc
expand collapse
Mass Spectrum Mass spectrum (electron ionization)
expand collapse

Related Compound Information

Coming Soon
Coming Soon
Coming Soon