biphenyl

CAS No. 92-52-4

Formula: C12H10
Basic Info

Biphenyl (or diphenyl or phenylbenzene or 1,1′-biphenyl or lemonene) is an organic compound that forms colorless crystals.
It has a distinctively pleasant smell. Biphenyl is an aromatic hydrocarbon with a molecular formula (C6H5)2. It is notable as a starting material for the production of polychlorinated biphenyls (PCBs), which were once widely used as dielectric fluids and heat transfer agents.
Biphenyl is also an intermediate for the production of a host of other organic compounds such as emulsifiers, optical brighteners, crop protection products, and plastics. Biphenyl is insoluble in water, but soluble in typical organic solvents. The biphenyl molecule consists of two connected phenyl rings.

Formula
C12H10
Molecular Weight
154.208
Exact Mass
154.078
LogP
3.3536
PSA
0
Synonyms

1,1‘-Biphenyl

mcs1572

Lemonene

DIPHENYL

Bibenzene

PHPH

FEMA 3129

Biphenyl

cp390

carolidal

Xenene

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Properties
Appearance & Physical State
White crystals
Density
0.992
Boiling Point
255ºC
Melting Point
68.5-71ºC
Flash Point
113ºC
Refractive Index
1.475
Stability
Stable. Combustible. Incompatible with strong oxidising agents.
Storage Condition
0-6ºC
Safety Info
Safety Statements
S23-S60-S61
Risk Statements
R36/37/38; R50/53
HS Code
2902909010
RIDADR
UN 3077
Packing Group
III
Hazard Codes
MSDS
SDS 1.0
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SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name biphenyl

1.2 Other means of identification

Product number -
Other names 1,1‘-Biphenyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Biphenyl is used in organic syntheses, heat transfer fluids, dye carriers, food preservatives, as an intermediate for polychlorinated biphenyls, and as a fungistat in the packaging of citrus fruits.
Uses advised against no data available

1.4 Supplier's details

Company MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road,
Xuhui District, Shanghai, China
Telephone +86(21)64956998
Fax +86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-400-6021-666
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity – single exposure, Category 3

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Warning

Hazard statement(s)

H315 Causes skin irritation

H319 Causes serious eye irritation

H335 May cause respiratory irritation

H410 Very toxic to aquatic life with long lasting effects

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P273 Avoid release to the environment.

Response

P302+P352 IF ON SKIN: Wash with plenty of water/...

P321 Specific treatment (see ... on this label).

P332+P313 If skin irritation occurs: Get medical advice/attention.

P362+P364 Take off contaminated clothing and wash it before reuse.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P337+P313 If eye irritation persists: Get medical advice/attention.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P312 Call a POISON CENTER/doctor/…if you feel unwell.

P391 Collect spillage.

Storage

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
biphenyl biphenyl 92-52-4 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest. Refer for medical attention.

In case of skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap.

In case of eye contact

Rinse with plenty of water for several minutes (remove contact lenses if easily possible).

If swallowed

Rinse mouth. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

CALL FOR MEDICAL AID. VAPOR, MIST OR DUST: Irritating to eyes, nose, throat and skin. Flush affected area with plenty of water. IF IN EYES, hold eyelids open and flush with plenty of water. SOLID OR LIQUID: Irritating to skin and eyes, nose and throat. Remove contaminated clothing and shoes. Flush affected areas with plenty water. IF IN EYES, hold eyelids open and flush with plenty of water. If swallowed, do not induce vomiting. Harmful if inhaled or swallowed. Causes irritation to eyes, skin and mucous membrane and upper respiratory tract. Causes central nervous system depression, paralysis and convulsion in animals. May cause headache, diffuse gastrointestinal pain, nausea, indigestion, numbness and aching of limbs, and general fatigue. Liver function test may show abnormalities. Chronic exposure is mostly characterized by central nervous system symptoms, fatigue, headache, tremor, insomnia, sensory impairment, and mood changes. Such symptoms are rare however. (USCG, 1999)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Exposure treatment. Inhalation: Call for medical aid. Remove the victim to fresh air. If not breathing give artificial respiration. If breathing is difficult give oxygen. Ingestion: Do not induce vomiting. Skin: Wash with soap and copious amounts of water. Eyes: Flush with copious amounts of water for at least 15 min.

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Carbon dioxide, dry chemical, water spray, mist, fog.

5.2 Specific hazards arising from the chemical

Combustible. Emits toxic fumes under fire conditions. (USCG, 1999)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

6.3 Methods and materials for containment and cleaning up

Environmental considerations: Air spill: Apply water spray or mist to knock down vapors.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Separated from food and feedstuffs and oxidants. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.Materials... toxic as stored or which can decompose into toxic components... should be stored in a cool... ventilated place, out of... sun, away from fire hazard... /and/ be periodically inspected. ...Incompatible materials should be isolated...

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 1 mg/cu m (0.2 ppm).

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state White crystals
Colour White scales
Odour Pleasant, peculiar odor
Melting point/ freezing point 270°C(lit.)
Boiling point or initial boiling point and boiling range 256°C(lit.)
Flammability Combustible SolidCombustible.
Lower and upper explosion limit / flammability limit Lower flammable limit: 0.6% by volume (at 232 deg F, 111°C); Upper flammable limit: 5.8% by volume (at 311 deg F,155°C)
Flash point 77°C(lit.)
Auto-ignition temperature 540°C (USCG, 1999)
Decomposition temperature no data available
pH no data available
Kinematic viscosity 0.98 cSt at 100°C
Solubility Insoluble
Partition coefficient n-octanol/water (log value) log Kow = 4.01
Vapour pressure 0.005 mm Hg (NIOSH, 2016)
Density and/or relative density 0.992
Relative vapour density 5.31 (USCG, 1999) (Relative to Air)
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Very stable in acidic & alkaline media.

10.3 Possibility of hazardous reactions

Slight when exposed to heat or flame; can react with oxidizing materials.Dust explosion possible if in powder or granular form, mixed with air.BIPHENYL is incompatible with oxidizers.

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Reacts with oxidants causing fire and explosion hazard.

10.6 Hazardous decomposition products

This substance decomposes on heating producing toxic gases, acrid smokes and fumes.

11.Toxicological information

Acute toxicity

  • Oral: LD50 Rat oral 3280 mg/kg
  • Inhalation: LC50 Mouse inhalation 0.275 mg/L/4 hr
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Cancer Classification: Group D Not Classifiable as to Human Carcinogenicity

Reproductive toxicity

No information is available on the reproductive or developmental effects of biphenyl in humans. Limited data indicate that biphenyl does not cause teratogenic effects (birth defects) in animals. Some evidence (not significant) of fetotoxicity has been observed in rats exposed to high levels of biphenyl via gavage (experimentally placing the chemical in the stomach).

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: LC50 Lepomis macrochirus (Bluegill) 4.7 mg/L/96 hr (95% confidence interval: 4.3-5.1 mg/L); static
  • Toxicity to daphnia and other aquatic invertebrates: EC50 Daphnia magna (Water flea; intoxication, immobilization) 7.1 mmol/cu m/48 hr; static
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

Several organisms have been found that can grow on diphenyl and use it as the sole carbon source.

12.3 Bioaccumulative potential

Bioconcentration factors for biphenyl in golden orfe (Leuciscus idus melanotus) and the amphipod Rhepoxynius abronius, have been measured as 280(1) and 4,500(2). Measured BCF values for rainbow trout (Salmo gairdneri) were reported as 437(3) and 1,318(4). According to a classification scheme(5), these BCF values indicate that bioconcentration in aquatic organisms is high to very high(SRC). Bivalve molluscs, Mercenaria mercenaria L., exposed to waste crankcase oil containing biphenyl for 2 days, did not significantly depurate biphenyl over a 45 day period in clean water(6).

12.4 Mobility in soil

In three soils, the log Koc was determined to be in the range 2.94-3.52 (Koc of 871-3,331)(1). The experimental mean log Koc value in five soils was 3.16 (Koc of 1,445)(3). The log Koc value in humic acids was determined to be 3.27 (Koc of 1,862)(4). According to a recommended classification scheme(2), these log Koc values indicate biphenyl may have low to slight mobility in soil(SRC). A log Koc of 5.09 was measured using soot columns and an SRM-1650 soot standard obtained from NIST(5). A retardation factor (Rf) of 2.1 was measured for biphenyl using soil columns filled with a surface soil (organic carbon = 12.6%, 60.3% sand, 24.0% silt, 15.7% clay, porosity = 0.7)(6). A retardation factor of 2.2-2.3 was measured for biphenyl on columns packed with low carbon aquifer material(7). The sorption of biphenyl on HDTMA clays indicated that sorption occurs via partition interactions with the HDTMA-derived organic phase. The greater the HDTMA content and the larger spacings of high charge HDTMA clays increased biphenyl's sorption(8).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN3077 IMDG: UN3077 IATA: UN3077

14.2 UN Proper Shipping Name

ADR/RID: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
IMDG: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
IATA: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.

14.3 Transport hazard class(es)

ADR/RID: 9 IMDG: 9 IATA: 9

14.4 Packing group, if applicable

ADR/RID: III IMDG: III IATA: III

14.5 Environmental hazards

ADR/RID: yes IMDG: yes IATA: yes

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
biphenyl biphenyl 92-52-4 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 16, 2017
Revision Date Aug 16, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
MSDS
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Name: Biphenyl Material Safety Data Sheet
Synonym: Diphenyl
CAS: 92-52-4
Section 1 - Chemical Product   MSDS Name:Biphenyl Material Safety Data Sheet
Synonym:Diphenyl

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
92-52-4 Biphenyl 99 202-163-5
Hazard Symbols: XI N
Risk Phrases: 36/37/38 50/53

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Dangerous for the environment.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes severe skin irritation. May be absorbed through the skin.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause gastric disturbances and electrolytic imbalance.
May cause systemic toxic effects on the heart, liver, and kidneys.
May cause central nervous system depression.
Inhalation:
Dust is irritating to the respiratory tract. Causes irritation of the mucous membrane and upper respiratory tract. Inhalation may cause headache, numbness of the limbs, flaccid paralysis, nausea, or vomiting.
Chronic:
Prolonged or repeated skin contact may cause sensitization dermatitis and possible destruction and/or ulceration. May cause liver and kidney damage. May cause digestive tract and cardiac disturbances. Repeated exposure may cause central nervous system damage. Laboratory experiments have resulted in mutagenic effects.

Section 4 - FIRST AID MEASURES
  Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion.
Extinguishing Media:
Water spray may cause frothing. Use carbon dioxide, dry chemical, or water fog. Solid streams of water or high volume water jet may spread fire.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Reduce airborne dust and prevent scattering by moistening with water. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Minimize dust generation and accumulation.
Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 92-52-4: United States OSHA: 0.2 ppm TWA; 1 mg/m3 TWA Belgium - TWA: 0.2 ppm VLE; 1.3 mg/m3 VLE Germany: 0.16 ppm TWA; 1 mg/m3 TWA Germany: Skin absorber Malaysia: 0.2 ppm TWA; 1.3 mg/m3 TWA Netherlands: 0.2 ppm MAC; 1 mg/m3 MAC Spain: 0.2 ppm VLA-ED; 1.3 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Crystals
Color: white
Odor: pleasant odor - butter-like
pH: Not available.
Vapor Pressure: 9.46 mmHg @ 115
Viscosity: Not available.
Boiling Point: 255 deg C
Freezing/Melting Point: 69-72 deg C
Autoignition Temperature: 540 deg C ( 1,004.00 deg F)
Flash Point: 113 deg C ( 235.40 deg F)
Explosion Limits, lower: 0.6 vol %
Explosion Limits, upper: 5.8 vol %
Decomposition Temperature:
Solubility in water: Insoluble.
Specific Gravity/Density: 0.991
Molecular Formula: C12H10
Molecular Weight: 154.07

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 92-52-4: DU8050000 LD50/LC50:
CAS# 92-52-4: Draize test, rabbit, eye: 100 mg Mild; Draize test, rabbit, skin: 500 uL/24H Severe; Oral, mouse: LD50 = 1900 mg/kg; Oral, rabbit: LD50 = 2400 mg/kg; Oral, rat: LD50 = 2140 mg/kg; Skin, rabbit: LD50 = >5010 mg/kg.
Carcinogenicity:
Biphenyl - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
  Ecotoxicity:
Fish: Fathead Minnow: LC50 = 1.2-3.3 mg/L; 96 Hr; Flow-through at 10 CWater flea Daphnia: EC50 = 0.63-3.91 mg/L; 48 Hr; (< 24 hrs old) Static at 22.2 C (pH 7.9-8.2)Bacteria: Phytobacterium phosphoreum: EC50 = 1.9-3.3 mg/L; 5,15,30 min; Microtox test at 15CVolatilization from moist soil surfaces will occur, but it is not expected to be significant from dry soil surfaces. Biphenyl readily biodegrades aerobically in both soil and water with an increased rate of biodegradation following acclimation (resistent under anaerobic conditions). Biphenyl will volatilize from water surfaces. Estimated BCF value range = 280-4500. This value range suggests that biphenyl Other Harmful to aquatic life in very low concentrations.

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:
USA RQ: CAS# 92-52-4: 100 lb final RQ; 45.4 kg final RQ

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI N
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
R 50/53 Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 23 Do not inhale gas/fumes/vapour/spray.
S 60 This material and its container must be
disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 92-52-4: 2
Canada
CAS# 92-52-4 is listed on Canada's DSL List.
CAS# 92-52-4 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 92-52-4 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Spectrum
NMR Spectrum 1H NMR : 400 MHz in CDCl3
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IR Spectrum IR : nujol mull
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Mass Spectrum Mass
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Raman Spectrum Raman : 4880 A,200 M,powder
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ESR Spectrum ESR : ANION RADICAL, REDUCTION WITH NA IN MTHF, ENDOR
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Toxicity
ACUTE TOXICITY DATA
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Type of Test
TCLo - Lowest published toxic concentration
Exposure Route
Inhalation
Species Observed
Human
Dose/Duration
4400 ug/m3
Toxic Effects
Peripheral Nerve and Sensation--flaccid paralysis without anesthesia (usually neuromuscular blockage)<br>Gastrointestinal--nausea or vomiting<br>Gastrointestinal--other changes
Reference
Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 26,70,1973
OTHER MULTIPLE DOSE TOXICITY DATA
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Type of Test
TDLo - Lowest published toxic dose
Exposure Route
Oral
Species Observed
Rodent - rat
Dose/Duration
3300 mg/kg/15D-I
Toxic Effects
Kidney, Ureter, Bladder--changes in bladder weight<br>Blood--changes in serum composition (e.g. TP, bilirubin, cholesterol)<br>Biochemical-Enzyme inhibition, induction, or change in blood or tissue levels-phosphatases
Reference
Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 57,414,1981
OTHER MULTIPLE DOSE TOXICITY DATA
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Type of Test
TDLo - Lowest published toxic dose
Exposure Route
Oral
Species Observed
Rodent - rat
Dose/Duration
41250 mg/kg/24W-C
Toxic Effects
Kidney, Ureter, Bladder--changes in tubules (including acute renal failure, acute tubular necrosis)<br>Kidney, Ureter, Bladder--urine volume increased
Reference
Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,560,1961

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