1.Identification
1.1 GHS Product identifier
| Product name | 2-Butanone peroxide |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | Hi-Point 90 (in DMP) |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | For industry use only. Oxidizing/reducing agents,Process regulators |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
| Company | MOLBASE (Shanghai) Biotechnology Co., Ltd. |
|---|---|
| Address | Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road, Xuhui District, Shanghai, China |
| Telephone | +86(21)64956998 |
| Fax | +86(21)54365166 |
1.5 Emergency phone number
| Emergency phone number | +86-400-6021-666 |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
2.Hazard identification
2.1 Classification of the substance or mixture
Organic peroxides, Type D
Acute toxicity - Oral, Category 4
Skin corrosion, Category 1B
Serious eye damage, Category 1
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |    |
|---|---|
| Signal word | Danger |
| Hazard statement(s) | H242 Heating may cause a fire H302 Harmful if swallowed H314 Causes severe skin burns and eye damage |
| Precautionary statement(s) | |
| Prevention | P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P234 Keep only in original packaging. P235 Keep cool. P240 Ground and bond container and receiving equipment. P280 Wear protective gloves/protective clothing/eye protection/face protection. P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P260 Do not breathe dust/fume/gas/mist/vapours/spray. |
| Response | P370+P378 In case of fire: Use ... to extinguish. P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell. P330 Rinse mouth. P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower]. P363 Wash contaminated clothing before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P310 Immediately call a POISON CENTER/doctor/… P321 Specific treatment (see ... on this label). P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |
| Storage | P403 Store in a well-ventilated place. P410 Protect from sunlight. P411 Store at temperatures not exceeding …°C/…°F. P420 Store separately. P405 Store locked up. |
| Disposal | P501 Dispose of contents/container to ... |
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| 2-Butanone peroxide | 2-Butanone peroxide | 1338-23-4 | none | 100% |
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
Fresh air, rest. Half-upright position. Refer for medical attention.
In case of skin contact
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
In case of eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
If swallowed
Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
Extremely destructive to tissue of the mucous membranes, upper respiratory tract, eyes, and skin. Symptoms of exposure include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. (USCG, 1999)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Peroxides should be washed promptly from the skin to prevent irritation. In the case of eye contact, the eyes should be flushed immediately with large amounts of water, and medical attention should be obtained. ... Medical attention should also be obtained in case of accidental ingestion. ... /Peroxides, Organic and Inorganic/
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
In case of fire, water should be applied by the sprinkler system or by hose from a safe distance, preferably with a fog nozzle. Foam may be necessary instead if the peroxide is diluted in a low density flammable solvent. Portable extinguishers should not be used except for very small fires. Peroxides threatened by fire should be wetted from a safe distance for cooling. /Peroxides, Organic and Inorganic/
5.2 Specific hazards arising from the chemical
Behavior in Fire: Explosive. (USCG, 1999)
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Personal protection: chemical protection suit including self-contained breathing apparatus. Collect leaking and spilled liquid in sealable plastic containers as far as possible. Do NOT absorb in saw-dust or other combustible absorbents.
6.3 Methods and materials for containment and cleaning up
Spills should be cleaned up promptly using non-sparking tools and an inert, moist diluent such as vermiculite or sand. Sweepings may be placed in open containers or polyethylene bags and the area washed with water and detergent. Spilled, contaminated, waste or questionable peroxides should be destroyed. /Peroxides, Organic and Inorganic/
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Store only if stabilized. Well closed. See Chemical Dangers.
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
Recommended Exposure Limit: Ceiling Value: 0.2 ppm (1.5 mg/cu m).
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
| Physical state | clear liquid |
|---|---|
| Colour | Colorless liquid |
| Odour | Typical odor-resembles that of acetone. |
| Melting point/ freezing point | 110ºC |
| Boiling point or initial boiling point and boiling range | 19ºC |
| Flammability | Combustible LiquidCombustible. Gives off irritating or toxic fumes (or gases) in a fire. |
| Lower and upper explosion limit / flammability limit | no data available |
| Flash point | 74°C |
| Auto-ignition temperature | 555.56°C Component 2 (83.33%: LACTOSE) |
| Decomposition temperature | >80°C |
| pH | no data available |
| Kinematic viscosity | no data available |
| Solubility | In water:0.1-0.5 g/100 mL at 22 ºC |
| Partition coefficient n-octanol/water (log value) | no data available |
| Vapour pressure | 8.05E-05mmHg at 25°C |
| Density and/or relative density | 0.99g/mLat 25°C |
| Relative vapour density | Component 2 (83.33%: LACTOSE): 6.69 (Relative to Air) |
| Particle characteristics | no data available |
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
UNSTABLE AGENT WHICH LIKE HYDROGEN PEROXIDE RELEASES OXYGEN.
10.3 Possibility of hazardous reactions
METHYL ETHYL KETONE PEROXIDE is a strong oxidizing agent. May be ignited by heat, sparks or flame and undergoes self-accelerating decomposition. Explosive decomposition occurs at 110°C. Sensitive to sunlight. Ignition and/or explosion may occur if mixed with readily oxidizable materials. Reacts with combustible materials such as wood, cloth or organic materials, with chlorine, and with metals (iron, copper and their alloys and aluminum and its alloys). Incompatible with strong oxidizing agents, strong reducing agents, natural rubbers, synthetic rubbers and chemical accelerators. Incompatible with heavy metals, acids and bases.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Vigorous decomp can be stimulated by even trace amt of a wide variety of contaminants, such as strong acids, bases, metals, metal alloys and salts, sulfur cmpd, amines, accelerators or reducing agents. This is particularly true of methyl ethyl ketone and benzoyl peroxides, which are intentionally stimulated to decomp @ room temp using small amt of accelerators.
10.6 Hazardous decomposition products
no data available
11.Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 6.86 ml/kg
- Inhalation: LC50 Mouse /inhalation/ 170 ppm/4 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
no data available
12.3 Bioaccumulative potential
An estimated BCF of 13 was calculated for the 2-butanone peroxide mixture(SRC), using an estimated log Kow of 2(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low. Chemical degradation is expected to be the dominant fate process in water because of reaction with organic matter and therefore, it is doubtful that un-reacted 2-butanone peroxide would be biologically available(SRC).
12.4 Mobility in soil
2-Butanone peroxide is a mixture dimers (50%), trimers (25%), and monomer peroxy compounds(3). Using a structure estimation method based on molecular connectivity indices(1), the Koc for 2-butanone peroxide can be estimated to range from 10 to 11,000(SRC). According to a classification scheme(2), this estimated Koc range suggests that some portions of the 2-butanone peroxide mixture are expected to have very high mobility in soil, whereas other portions of the mixture are expected to be essentially immobile. 2-Butanone peroxide is a strong oxidizing agent(3) and may decompose when brought in contact with organic materials(SRC).
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
14.Transport information
14.1 UN Number
| ADR/RID: UN3105 | IMDG: UN3105 | IATA: UN3105 |
14.2 UN Proper Shipping Name
| ADR/RID: ORGANIC PEROXIDE TYPE D, LIQUID |
| IMDG: ORGANIC PEROXIDE TYPE D, LIQUID |
| IATA: ORGANIC PEROXIDE TYPE D, LIQUID |
14.3 Transport hazard class(es)
| ADR/RID: 5.2 | IMDG: 5.2 | IATA: 5.2 |
14.4 Packing group, if applicable
| ADR/RID: II | IMDG: II | IATA: II |
14.5 Environmental hazards
| ADR/RID: no | IMDG: no | IATA: no |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| 2-Butanone peroxide | 2-Butanone peroxide | 1338-23-4 | none |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
16.Other information
Information on revision
| Creation Date | Aug 12, 2017 |
|---|---|
| Revision Date | Aug 12, 2017 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
