furan

CAS No. 110-00-9

Formula: C4H4O
Basic Info

Furan is a heterocyclic organic compound, consisting of a five-membered aromatic ring with four carbon atoms and one oxygen. The class of compounds containing such rings are also referred to as furans.
Furan is a colorless, flammable, highly volatile liquid with a boiling point close to room temperature. It is soluble in common organic solvents, including alcohol, ether, and acetone, and is slightly soluble in water. It is toxic and may be carcinogenic in humans. Furan is used as a starting point to other specialty chemicals.

Formula
C4H4O
Molecular Weight
68.074
Exact Mass
68.0262
LogP
1.2796
PSA
13.14
Synonyms

tetrole oxide

Oxacyclopentadiene

1,4-Epoxy-1,3-butadiene

Oxole

Divinylene oxide

Axole

Tetrole

Furan

expand collapse

Properties
Appearance & Physical State
colourless liquid
Density
0.936
Boiling Point
31.3ºC
Melting Point
-85.6ºC
Flash Point
-35ºC
Refractive Index
1.4197-1.4217
Water Solubility
insoluble
Stability
Stable. Substances to be avoided include strong oxidising agents, acids, peroxides and oxygen. Highly flammable; can form explosive mixtures with air.
Storage Condition
2-8ºC
Vapor Density
2.35 (vs air)
Vapor Pressure
1672 mm Hg ( 55 °C)
Safety Info
RTECS
OB3870000
Safety Statements
S45-S53-S61
WGK Germany
3
Risk Statements
R12; R19; R20/22; R38; R45; R48/22; R52/53; R68
HS Code
2932999060
RIDADR
UN 2389
Hazard Class
3
Packing Group
I
Hazard Codes
MSDS
SDS 1.0
expand collapse
Download/Modify | Technical supported by XiXisys.com. For US version, EU version (23 languages) and more, please refer to xixisys.com/en/sds/search

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name furan

1.2 Other means of identification

Product number -
Other names tetrole oxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Food Contaminant: CONTAMINANT
Uses advised against no data available

1.4 Supplier's details

Company MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road,
Xuhui District, Shanghai, China
Telephone +86(21)64956998
Fax +86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-400-6021-666
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Flammable liquids, Category 1

Acute toxicity - Oral, Category 4

Skin irritation, Category 2

Acute toxicity - Inhalation, Category 4

Germ cell mutagenicity, Category 2

Carcinogenicity, Category 1B

Specific target organ toxicity – repeated exposure, Category 2

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Danger

Hazard statement(s)

H224 Extremely flammable liquid and vapour

H302 Harmful if swallowed

H315 Causes skin irritation

H332 Harmful if inhaled

H341 Suspected of causing genetic defects

H350 May cause cancer

H412 Harmful to aquatic life with long lasting effects

Precautionary statement(s)
Prevention

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

P233 Keep container tightly closed.

P240 Ground and bond container and receiving equipment.

P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.

P242 Use non-sparking tools.

P243 Take action to prevent static discharges.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and understood.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P273 Avoid release to the environment.

Response

P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].

P370+P378 In case of fire: Use ... to extinguish.

P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell.

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P321 Specific treatment (see ... on this label).

P332+P313 If skin irritation occurs: Get medical advice/attention.

P362+P364 Take off contaminated clothing and wash it before reuse.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P312 Call a POISON CENTER/doctor/…if you feel unwell.

P308+P313 IF exposed or concerned: Get medical advice/ attention.

P314 Get medical advice/attention if you feel unwell.

Storage

P403+P235 Store in a well-ventilated place. Keep cool.

P405 Store locked up.

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
furan furan 110-00-9 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest. Half-upright position. Administration of oxygen may be needed. Refer immediately for medical attention.

In case of skin contact

Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rinse mouth. Refer immediately for medical attention.

4.2 Most important symptoms/effects, acute and delayed

The vapors are narcotic. Acute exposure to furan by inhalation may involve both reversible and irreversible changes. Acute exposure by ingestion or skin absorption, as well as chronic exposure, are associated with high toxicity. (EPA, 1998)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Aliphatic hydrocarbons and related compounds/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may spread fire. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide.

5.2 Specific hazards arising from the chemical

Very dangerous, upon exposure to heat or flame. It may form unstable peroxides on exposure to air. Contact with acids can initiate a violent, heat producing reaction. Avoid acids, oxidizing agents. Upon standing in air, it may form unstable peroxides. (EPA, 1998)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: self-contained breathing apparatus. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

6.3 Methods and materials for containment and cleaning up

Evacuate and restrict persons not wearing protective equipment from area of spill or leak until cleanup is complete. Avoid breathing vapors. Keep upwind. Do not handle broken packages without protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. Shut off ignition sources; no flares, smoking, or flames in hazard area. Stop leak if you can do so without risk. Use water spray to reduce vapors. Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal. Large spills: dike far ahead of spill for later disposal. The exposure concentration limit of 10 ppm together with the low boiling point of furan requires that adequate ventilation be provided in areas handling this chemical. Establish forced ventilation to keep levels below explosive limit. Contact with liquid must be avoided since this chemical can be absorbed through the skin. Keep furan out of a confined space, such as a sewer, because of the possibility of an explosion, unless the sewer is designed to prevent the build-up of explosive concentrations. Thorough washing with soap and water followed by prolonged rinsing should be done immediately after accidental contact. It may be necessary to contain and dispose of this chemical as a hazardous waste. If material or contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Contact your Department of Environmental Protection or your regional office of the federal EPA for specific recommendations.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Fireproof. Well closed. Cool. Keep in the dark. Store only if stabilized. Separated from strong oxidants and acids. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.Before entering confined space where this chemical may be present, check to make sure that an explosive concentration does not exist. Store in an explosion-proof refrigerator. Keep in a tightly closed container under an inert atmosphere and protect from light for long-term storage. A regulated, marked area should be established where this chemical is handled, used, or stored ...

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state colourless liquid
Colour Colorless liquid, turns brown upon standing; color change is retarded if a small amount of water is added
Odour Ethereal
Melting point/ freezing point 226°C(lit.)
Boiling point or initial boiling point and boiling range 31°C
Flammability Extremely flammable.
Lower and upper explosion limit / flammability limit Lower 2.3%, upper 14.3% (% by vol)
Flash point -35°C(lit.)
Auto-ignition temperature 390°C
Decomposition temperature no data available
pH no data available
Kinematic viscosity 0.38 cP at 20°C
Solubility In water:insoluble
Partition coefficient n-octanol/water (log value) log Kow = 1.34
Vapour pressure 1672 mm Hg ( 55 °C)
Density and/or relative density 0.936
Relative vapour density 2.35 (vs air)
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

A very dangerous fire hazard when exposed to heat or flame.The vapour is heavier than air and may travel along the ground; distant ignition possible.FURAN is sensitive to heat and may turn brown upon standing. This compound may be light sensitive. When uninhibited, this compound forms explosive peroxides on exposure to air. This chemical may react with oxidizers, acids, peroxides and oxygen. It resinifies on evaporation or when in contact with mineral acids, but it is stable in alkalis. .

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Violent reaction with acids, oxidizers. Unless stablized with an inhibitor, air exposure forms unstable peroxides.

10.6 Hazardous decomposition products

When heated to decomposition it emits acrid smoke and irritating fumes.

11.Toxicological information

Acute toxicity

  • Oral: no data available
  • Inhalation: LC50 Rat inhalation 3398 ppm/1 hr
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Evaluation: There is inadequate evidence in humans for the carcinogenicity of furan. There is sufficient evidence in experimental animals for the carcinogenicity of furan. Overall evaluation: Furan is possibly carcinogenic to humans (Group 2B).

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: EC50; Species: Pimephales promelas (Fathead minnow, age 29-31 days, length 18 mm, weight 0.100 g); Conditions: freshwater, flow through, 23.2 (22.0-24.6)°C, pH 8.00, hardness 44.5 mg/L CaCO3, alkalinity 41.5 mg/L CaCO3, dissolved oxygen 80.0% (65.5-87.4%); Concentration: 99000 ug/L for 24 hr; Effect: behavior change, equilibrium /> or = 99% pure
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: Furan, present at 100 mg/L, reached 4% of its theoretical BOD in 8 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1). Adaptation (time to reach 5% reduction) and degradation (total time to reach <1 ug/L) times for aerobic degradation of furan (initial concentrations 150-250 ug/L and 50 times dilution) in a mixture of aromatic hydrocarbons and nitrogen, sulfur, oxygen containing compounds were 390 and 160 hours, and 530 and 340 hours, for the two concentrations, respectively(2).

12.3 Bioaccumulative potential

BCFs of 0.9-1.5 and <3.2-13 were measured in carp (Cyprinus carpio) at furan concentrations of 1 and 0.1 mg/L, respectively(1). According to a classification scheme(2), these BCFs suggest the potential for bioconcentration in aquatic organisms is low(SRC).

12.4 Mobility in soil

Using a structure estimation method based on molecular connectivity indices(1), the Koc of furan can be estimated to be 80(SRC). According to a classification scheme(2), this estimated Koc value suggests that furan is expected to have high mobility in soil.

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN2389 IMDG: UN2389 IATA: UN2389

14.2 UN Proper Shipping Name

ADR/RID: FURAN
IMDG: FURAN
IATA: FURAN

14.3 Transport hazard class(es)

ADR/RID: 3 IMDG: 3 IATA: 3

14.4 Packing group, if applicable

ADR/RID: II IMDG: II IATA: II

14.5 Environmental hazards

ADR/RID: no IMDG: no IATA: no

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
furan furan 110-00-9 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Not Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 10, 2017
Revision Date Aug 10, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
MSDS
expand collapse
Name: Furan stabilized with 0.025-0.04% BHT Material Safety Data Sheet
Synonym: Divinylene oxide; Oxacyclopentadiene; Furfuran; Tetrol; 1,4-Epoxy-1,3-butadiene; Oxole
CAS: 110-00-9
Section 1 - Chemical Product   MSDS Name:Furan stabilized with 0.025-0.04% BHT Material Safety Data Sheet
Synonym:Divinylene oxide; Oxacyclopentadiene; Furfuran; Tetrol; 1,4-Epoxy-1,3-butadiene; Oxole

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
110-00-9 Furan 98 203-727-3
Hazard Symbols: T F+
Risk Phrases: 12 19 20/22 38 45 48/22 52/53

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Extremely flammable. May form explosive peroxides. Harmful by inhalation and if swallowed. Irritating to skin. May cause cancer.
Harmful : danger of serious damage to health by prolonged exposure if swallowed. Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.Cancer suspect agent.
Potential Health Effects
Eye:
May cause eye irritation. At high concentrations may cause lacrimation (tearing) and irritation.
Skin:
May cause skin irritation. May be absorbed through the skin in harmful amounts. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Ingestion:
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver damage. Possible aspiration hazard.
Inhalation:
Harmful if inhaled. Irritation may lead to chemical pneumonitis and pulmonary edema. Vapors may cause dizziness or suffocation. May cause nausea, dizziness, and headache. Inhalation may cause respiratory tract irritation, oppression in the chest, dyspnea (labored breathing), central nervous system depression, and temporary visual disturbances. Exposure to high concentrations may produce narcosis, nausea and loss of consciousness.
Chronic:
Chronic exposure may cause liver damage.

Section 4 - FIRST AID MEASURES
  Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove contaminated clothing and shoes. Get medical aid if irritation develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Will be easily ignited by heat, sparks or flame. Extremely flammable liquid and vapor. Vapor may cause flash fire. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
Water may be ineffective. Use dry chemical or foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Remove all sources of ignition.
Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing.
Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. If peroxide formation is suspected, do not open or move container. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Do not distill since this removes peroxide-inhibitors. Use only with adequate ventilation.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area. Regularly check inhibitor levels to maintain peroxide levels below 1%. After opening, purge container with nitrogen before reclosing. Periodically test for peroxide formation on long-term storage. Addition of water or appropriate reducing materials will lessen peroxide formation.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Ventilation fans and other electrical service must be non-sparking and have an explosion-proof design. Use only under a chemical fume hood. Utilize a closed system process where feasible.
Exposure Limits CAS# 110-00-9: Russia: 0.5 mg/m3 TWA CAS# 128-37-0: United Kingdom, WEL - TWA: 10 mg/m3 TWA United Kingdom, WEL - STEL: 30 mg/m3 STEL Belgium - TWA: 10 mg/m3 VLE France - VME: 10 mg/m3 VME Germany: 10 mg/m3 TWA (inhalable fraction) Malaysia: 10 mg/m3 TWA Netherlands: 10 mg/m3 MAC Personal Protective Equipment Eyes: Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Liquid
Color: clear, colorless
Odor: pleasant odor - ether-like
pH: Not available.
Vapor Pressure: 600 mm Hg @ 25 deg C
Viscosity: 0.38cP @ 20C
Boiling Point: 31.3 deg C
Freezing/Melting Point: -85.6 deg C
Autoignition Temperature: 360 deg C ( 680.00 deg F)
Flash Point: -35 deg C ( -31.00 deg F)
Explosion Limits, lower: 2.3%
Explosion Limits, upper: 14.3%
Decomposition Temperature:
Solubility in water: Insoluble.
Specific Gravity/Density: 0.93 g/cm3
Molecular Formula: C4H4O
Molecular Weight: 68.08

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
May form peroxides in the absence of inhibitors. May discolor on exposure to air. Under normal storage conditions, peroxidizable compounds can form and accumulate peroxides which may explode when subjected to heat or shock. This material is most hazardous when peroxide levels are concentrated by distillation or evaporation.
Conditions to Avoid:
Ignition sources, excess heat, evaporating to near dryness, prolonged exposure to air.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, oxygen.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 110-00-9: LT8524000 CAS# 128-37-0: GO7875000 LD50/LC50:
CAS# 110-00-9: Inhalation, mouse: LC50 = 120 mg/m3/1H; Inhalation, rat: LC50 = 3398 ppm/1H.
CAS# 128-37-0: Draize test, rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, skin: 500 mg/48H Moderate; Oral, mouse: LD50 = 650 mg/kg; Oral, mouse: LD50 = 1040 mg/kg; Oral, rabbit: LD50 = 2100 mg/kg; Oral, rat: LD50 = 890 mg/kg.
For furan, CAS 110-00-9, oral LDLo (dog): 234 mg/kg.
Carcinogenicity:
Furan - California: carcinogen, initial date 10/1/93 NTP: Suspect carcinogen IARC: Group 2B carcinogen BHT - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
  Other No information available.

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: FURAN
Hazard Class: 3
UN Number: 2389
Packing Group: I
IMO
Shipping Name: FURAN
Hazard Class: 3.1
UN Number: 2389
Packing Group: I
RID/ADR
Shipping Name: FURAN
Hazard Class: 3
UN Number: 2389
Packing group: I
USA RQ: CAS# 110-00-9: 100 lb final RQ; 45.4 kg final RQ

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T F+
Risk Phrases:
R 45 May cause cancer.
R 12 Extremely flammable.
R 19 May form explosive peroxides.
R 20/22 Harmful by inhalation and if swallowed.
R 38 Irritating to skin.
R 48/22 Harmful : danger of serious damage to health
by prolonged exposure if swallowed.
R 52/53 Harmful to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 110-00-9: No information available.
CAS# 128-37-0: 1
Canada
CAS# 110-00-9 is listed on Canada's DSL List.
CAS# 128-37-0 is listed on Canada's DSL List.
CAS# 110-00-9 is not listed on Canada's Ingredient Disclosure List.
CAS# 128-37-0 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 110-00-9 is listed on the TSCA inventory.
CAS# 128-37-0 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Spectrum
NMR Spectrum 1H NMR : 90 MHz in CDCl3
expand collapse
IR Spectrum IR : liquid film
expand collapse
Mass Spectrum Mass
expand collapse
Analysis Methods
Kovats' RI, non-polar column, isothermal
expand collapse
Column Shape
Capillary
Active Phase(℃)
SPB-1
Retention index
500.
Temperature Control
100.
Method
isothermal
Comments
60. m/0.32 mm/0.25 μm
Reference
Misharina, T.A.Beletsky, I.V.Golovnya, R.V.Chromatographic and IR characteristics of methyl-, formyl-, and acetyl-substituted furans and thiophenesRuss. Chem. Bull. (Engl. Transl.)1994, 43, 1, 64-69.
Kovats' RI, non-polar column, isothermal
expand collapse
Column Shape
Packed
Active Phase(℃)
SE-30
Retention index
498.
Temperature Control
100.
Method
isothermal
Comments
Gaschrom Q; Column length: 2. m
Reference
Winskowski, J.Gaschromatographische Identifizierung von Stoffen anhand von Indexziffem und unterschiedlichen DetektorenChromatographia1983, 17, 3, 160-165.
Kovats' RI, non-polar column, isothermal
expand collapse
Column Shape
Packed
Active Phase(℃)
Apiezon L
Retention index
483.
Temperature Control
120.
Method
isothermal
Comments
Celite 545
Reference
Bogoslovsky, Yu.N.Anvaer, B.I.Vigdergauz, M.S.Chromatographic constants in gas chromatography (in Russian)Standards Publ. House, Moscow, 1978, 192.
Kovats' RI, non-polar column, isothermal
expand collapse
Column Shape
Packed
Active Phase(℃)
Apiezon L
Retention index
492.
Temperature Control
160.
Method
isothermal
Comments
Celite 545
Reference
Bogoslovsky, Yu.N.Anvaer, B.I.Vigdergauz, M.S.Chromatographic constants in gas chromatography (in Russian)Standards Publ. House, Moscow, 1978, 192.
Kovats' RI, non-polar column, isothermal
expand collapse
Column Shape
Packed
Active Phase(℃)
SE-30
Retention index
485.
Temperature Control
80.
Method
isothermal
Comments
He, Chromosorb P; Column length: 6. m
Reference
Viani, R.Müggler-Chavan, F.Reymond, D.Egli, R.H.196. Sur la composition de l'arôme de caféHelv. Chim. Acta1965, 48, 195-196, 1809-1815.
Toxicity
OTHER MULTIPLE DOSE TOXICITY DATA
expand collapse
Type of Test
TDLo - Lowest published toxic dose
Exposure Route
Oral
Species Observed
Rodent - rat
Dose/Duration
240 mg/kg/16D-I
Toxic Effects
Liver--other changes<br>Nutritional and Gross Metabolic--weight loss or decreased weight gain
Reference
National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-402,1993
OTHER MULTIPLE DOSE TOXICITY DATA
expand collapse
Type of Test
TDLo - Lowest published toxic dose
Exposure Route
Oral
Species Observed
Rodent - rat
Dose/Duration
3900 mg/kg/13W-I
Toxic Effects
Liver--hepatitis (hepatocellular necrosis), zonal<br>Kidney, Ureter, Bladder--changes in tubules (including acute renal failure, acute tubular necrosis)<br>Endocrine--changes in thymus weight
Reference
National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-402,1993
OTHER MULTIPLE DOSE TOXICITY DATA
expand collapse
Type of Test
TCLo - Lowest published toxic concentration
Exposure Route
Inhalation
Species Observed
Rodent - rat
Dose/Duration
200 mg/m3/4H/60D-I
Toxic Effects
Lungs, Thorax, or Respiration--structural or functional change in trachea or bronchi<br>Liver--other changes<br>Related to Chronic Data--death
Reference
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961- Volume(issue)/page/year: 9,106,1967

Related Compound Information

PRODUCTS
Coming Soon
SUPPLIERS
Coming Soon
BRANDING
Coming Soon