2-Aminopyridine

CAS No. 504-29-0

Formula: C5H6N2
Basic Info

2-Aminopyridine is an organic compound with the formula H2NC5H4N. It is one of three isomeric aminopyridines. It is a colourless solid that is used in the production of the drugs piroxicam, sulfapyridine, tenoxicam, and tripelennamine. It is produced by the reaction of sodium amide with pyridine, the Chichibabin reaction.

Formula
C5H6N2
Molecular Weight
94.1145
Exact Mass
94.0531
LogP
1.245
PSA
38.91
Synonyms

2-Pyridylamine

A-PYRIDYLAMINE

Pyridin-2-amine

2-amino-pyridine

2-pyridinylamine

2-PYRIDINAMINE

2-AP,2-Pyridinamine,2-Pyridylamine

o-Aminopyridine

pyridin-2-ylamine

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Properties
Appearance & Physical State
white to yellow flakes
Density
1.107g/cm3
Boiling Point
204-210ºC
Melting Point
59-60ºC
Flash Point
92ºC
Refractive Index
1.56552 (65ºC)
Water Solubility
Slightly soluble. 1-5 g/100 mL at 19 ºC
Stability
Stable under normal temperatures and pressures.
Storage Condition
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.
Safety Info
RTECS
US1575000
Safety Statements
S28-S36/37/39-S38-S45
WGK Germany
3
Risk Statements
R25; R36/37/38
HS Code
2942000000
RIDADR
UN 2671
Hazard Class
6.1
Packing Group
II
Caution Statement
P261; P280; P301 + P310; P305 + P351 + P338; P312
Hazard Codes
MSDS
SDS 1.0
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SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Aminopyridine

1.2 Other means of identification

Product number -
Other names 2-Pyridylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

Company MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road,
Xuhui District, Shanghai, China
Telephone +86(21)64956998
Fax +86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-400-6021-666
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 3

Acute toxicity - Dermal, Category 4

Skin irritation, Category 2

Eye irritation, Category 2

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Danger

Hazard statement(s)

H301 Toxic if swallowed

H312 Harmful in contact with skin

H315 Causes skin irritation

H319 Causes serious eye irritation

H411 Toxic to aquatic life with long lasting effects

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P273 Avoid release to the environment.

Response

P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/…

P321 Specific treatment (see ... on this label).

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P312 Call a POISON CENTER/doctor/…if you feel unwell.

P362+P364 Take off contaminated clothing and wash it before reuse.

P332+P313 If skin irritation occurs: Get medical advice/attention.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P337+P313 If eye irritation persists: Get medical advice/attention.

P391 Collect spillage.

Storage

P405 Store locked up.

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
2-Aminopyridine 2-Aminopyridine 504-29-0 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.

In case of skin contact

Remove contaminated clothes. Rinse skin with plenty of water or shower.

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

Exposure Routes: inhalation, skin absorption, ingestion, skin and/or eye contact Symptoms: Irritation eyes, nose, throat; headache, dizziness; excitement; nausea; high blood pressure; respiratory distress; lassitude (weakness, exhaustion); convulsions; stupor Target Organs: central nervous system, respiratory system (NIOSH, 2016)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

IN CASES OF ACCIDENTAL SKIN CONTACT, PROMPT, THOROUGH SKIN CLEANSING & CLOTHING CHANGE ARE NECESSARY.

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Extinguishant: Carbon dioxide, dry chemical, alcohol foam

5.2 Specific hazards arising from the chemical

This chemical is combustible.

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations.

6.3 Methods and materials for containment and cleaning up

Cover with 9:1 mixture of sand and soda ash. After mixing, transfer into a paper carton, stuffed with ruffled paper. Burn ... in furnace with afterburner and scrubber.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Separated from food and feedstuffs, strong oxidants and strong acids.IN GENERAL MATERIALS ... TOXIC AS STORED OR WHICH CAN DECOMP INTO TOXIC COMPONENTS ... SHOULD BE STORED IN COOL, WELL-VENTILATED PLACE, OUT OF ... SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD, & SHOULD BE PERIODICALLY INSPECTED & MONITORED. INCOMPATIBLE MATERIALS SHOULD BE ISOLATED.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 0.5 ppm (2 mg/cu m).

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state white to yellow flakes
Colour White leaflets or large colorless crystals
Odour Characteristic odor
Melting point/ freezing point 220°C(dec.)(lit.)
Boiling point or initial boiling point and boiling range 204-210°C(lit.)
Flammability Combustible SolidCombustible. Gives off irritating or toxic fumes (or gases) in a fire.
Lower and upper explosion limit / flammability limit no data available
Flash point 92°C
Auto-ignition temperature no data available
Decomposition temperature no data available
pH BASE
Kinematic viscosity no data available
Solubility In water:Slightly soluble. 1-5 g/100 mL at 19 ºC
Partition coefficient n-octanol/water (log value) log Kow= 0.48
Vapour pressure 0.8 mm Hg at 25°C (NIOSH, 2016)
Density and/or relative density 1.107g/cm3
Relative vapour density 3.25 (Air= 1)
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

Dust explosion possible if in powder or granular form, mixed with air.2-AMINOPYRIDINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides. Reacts with oxidizing agents .

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Strong oxidizers

10.6 Hazardous decomposition products

DANGEROUS; WHEN HEATED TO DECOMP IT EMITS HIGHLY TOXIC FUMES OF /NITROGEN OXIDES/.

11.Toxicological information

Acute toxicity

  • Oral: LD50 Rat oral 0.2 g/kg
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: no data available
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: An aerobic biological screening study, which utilized a 10 mg/l yeast extract and an Aeric Ochraqualf soil for inocula, indicated that 2-aminopyridine is not readily biodegradable(1). At 28°C and a pH of 7, less than 1% of an initial 17 ppm of 2-aminopyridine was mineralized within 30 days as evidenced via the release of inorganic nitrogen(1). In addition, an acclimated aerobic soil grab sample study demonstrated slow biodegradation of 2-aminopyridine(2). 2-Aminopyridine was added to Fincastle silt loam (Aeric Ochraqualf) with a pH of 6.7 and incubated at 25°C(2). Within 64 days, 59.5% of the available nitrogen was released to inorganic forms(2). Sterilized controls lost 14.9% of the starting material to volatilization; but, did not release inorganic nitrogen(2). A screening test, which utilized 5 ml garden soil suspensions with glucose, yeast extract and mineral salts, compared aerobic and anaerobic biodegradation of 2-aminopyridine(3). 2-Aminopyridine completely degraded in greater than 96 days under both aerobic and anaerobic conditions(3). A 0% BOD was reported using 100 mg/l 2-aminopyridine in 30 mg/l sludge in 4 weeks(4).

12.3 Bioaccumulative potential

A BCF of 3.0-7.7 and <5.1-25 at a concentration of 0.1 and 0.01 mg/l, respectively, was measured for 2-aminopyridine(1). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low.

12.4 Mobility in soil

Using a structure estimation method based on molecular connectivity indices(1), the Koc for 2-aminopyridine can be estimated to be 45(SRC). According to a classification scheme(2), this estimated Koc value suggests that 2-aminopyridine is expected to have very high mobility in soil. However, the pKa of 2-aminopyridine is 6.86(3), indicating that this compound will partially exist in the protonated form in the environment and cations generally adsorb to organic carbon and clay more strongly than their neutral counterparts.

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN2671 IMDG: UN2671 IATA: UN2671

14.2 UN Proper Shipping Name

ADR/RID: AMINOPYRIDINES (o-, m-, p,)
IMDG: AMINOPYRIDINES (o-, m-, p,)
IATA: AMINOPYRIDINES (o-, m-, p,)

14.3 Transport hazard class(es)

ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1

14.4 Packing group, if applicable

ADR/RID: II IMDG: II IATA: II

14.5 Environmental hazards

ADR/RID: yes IMDG: yes IATA: yes

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
2-Aminopyridine 2-Aminopyridine 504-29-0 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 11, 2017
Revision Date Aug 11, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
MSDS
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Name: 2-Aminopyridine Material Safety Data Sheet
Synonym: alpha-Aminopyridine; Amino-2-pyridine; 1,2-Dihydro-2-iminopyridine; alpha-Pyridinamine; 2-Pyridinamine; alpha-Pyridylamine
CAS: 504-29-0
Section 1 - Chemical Product   MSDS Name:2-Aminopyridine Material Safety Data Sheet
Synonym:alpha-Aminopyridine; Amino-2-pyridine; 1,2-Dihydro-2-iminopyridine; alpha-Pyridinamine; 2-Pyridinamine; alpha-Pyridylamine

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
504-29-0 2-Aminopyridine > 99 207-988-4
Hazard Symbols: T
Risk Phrases: 25 36/37/38

Section 3 - HAZARDS IDENTIFICATION
  EMERGENCY OVERVIEW
Toxic if swallowed. Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation. Causes redness and pain.
Skin:
Causes skin irritation. May be fatal if absorbed through the skin.
Substance is rapidly absorbed through the skin. Causes symptoms similar to those of inhalation. Causes redness and pain.
Ingestion:
May be fatal if swallowed. May cause irritation of the digestive tract. Poison by ingestion. May cause effects similar to those for inhalation exposure.
Inhalation:
Causes respiratory tract irritation. May cause severe headaches, nausea, increased blood pressure, weakness, convulsions, and a stuporous state.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
  Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
  General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Containers may explode in the heat of a fire. Combustible solid.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
  General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Remove all sources of ignition. Provide ventilation.

Section 7 - HANDLING and STORAGE
  Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Keep away from heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
  Engineering Controls:
Use only under a chemical fume hood.
Exposure Limits CAS# 504-29-0: United Kingdom, WEL - TWA: 0.5 ppm TWA; 2 mg/m3 TWA United Kingdom, WEL - STEL: 2 ppm STEL; 7.8 mg/m3 STEL United States OSHA: 0.5 ppm TWA; 2 mg/m3 TWA Belgium - TWA: 0.5 ppm VLE; 1.9 mg/m3 VLE France - VME: 0.5 ppm VME; 2 mg/m3 VME Germany: 0.5 ppm TWA; 2 mg/m3 TWA Malaysia: 0.5 ppm TWA; 1.9 mg/m3 TWA Netherlands: 0.5 ppm MAC; 2 mg/m3 MAC Spain: 0.5 ppm VLA-ED; 1.9 mg/m3 VLA-ED Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
 
Physical State: Powder
Color: cream - beige
Odor: Faint, characteristic odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 204 - 210 deg C @ 760 mm Hg
Freezing/Melting Point: 59 - 60 deg C
Autoignition Temperature: Not available.
Flash Point: 92 deg C ( 197.60 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: soluble
Specific Gravity/Density:
Molecular Formula: C5H6N2
Molecular Weight: 94.12

Section 10 - STABILITY AND REACTIVITY
  Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Ignition sources, dust generation.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
  RTECS#:
CAS# 504-29-0: US1575000 LD50/LC50:
CAS# 504-29-0: Dermal, guinea pig: LD50 = 500 mg/kg; Oral, mouse: LD50 = 145 mg/kg; Oral, rat: LD50 = 200 mg/kg.
TCLo (Inhalation, Human) = 5 Carcinogenicity:
2-Aminopyridine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
  Ecotoxicity:
Fish: Bluegill/Sunfish: LC50 = 2.82 - 7.56 mg/L; 96 Hr.; 12-22 degrees CBacteria: Phytobacterium phosphoreum: EC50 = 248-284 mg/L; 5, 15, 30 minutes; Microtox test; 15 degrees CBioaccumulation: none or low

Section 13 - DISPOSAL CONSIDERATIONS
  Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION
 
IATA
Shipping Name: AMINOPYRIDINES
Hazard Class: 6.1
UN Number: 2671
Packing Group: II
IMO
Shipping Name: AMINOPYRIDINES
Hazard Class: 6.1
UN Number: 2671
Packing Group: II
RID/ADR
Shipping Name: AMINOPYRIDINES
Hazard Class: 6.1
UN Number: 2671
Packing group: II

Section 15 - REGULATORY INFORMATION
 
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 25 Toxic if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 28B After contact with skin, wash immediately with
plenty of water and soap.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 38 In case of insufficient ventilation, wear
suitable respiratory equipment.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 504-29-0: No information available.
Canada
CAS# 504-29-0 is listed on Canada's DSL List.
CAS# 504-29-0 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 504-29-0 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A
Spectrum
NMR Spectrum 1H NMR : 90 MHz in CDCl3
expand collapse
IR Spectrum IR : KBr disc
expand collapse
Mass Spectrum Mass
expand collapse
Analysis Methods
Kovats' RI, polar column, isothermal
expand collapse
Column Shape
Capillary
Active Phase(℃)
PEG-40M
Retention index
1892.
Temperature Control
150.
Method
isothermal
Comments
50. m/0.3 mm/0.4 μm, He
Reference
Terenina, M.B.Zhuravieva, I.L.Golovnya, R.V.Peculiar features of sorption of positional isomers of formyl-, acetyl-, and aminopyridines in capillary gas-liquid chromatographyRuss. Chem. Bull. (Engl. Transl.)1997, 46, 1, 86-89.
Kovats' RI, polar column, isothermal
expand collapse
Column Shape
Packed
Active Phase(℃)
PEG-2000
Retention index
1915.
Temperature Control
179.
Method
isothermal
Comments
He, Celite 545 (44-60 mesh); Column length: 3. m
Reference
Anderson, A.Jurel, S.Shymanska, M.Golender, L.Gas-liquid chromatography of some aliphatic and heterocyclic mono- and pollyfunctional amines. VII. Retention indices of amines in some polar and unpolar stationary phasesLatv. PSR Zinat. Akad. Vestis Kim. Ser.1973, 1, 51-63.
Kovats' RI, polar column, isothermal
expand collapse
Column Shape
Packed
Active Phase(℃)
PEG-2000
Retention index
1896.
Temperature Control
180.
Method
isothermal
Comments
He, Celite 545 (44-60 mesh); Column length: 3. m
Reference
Anderson, A.Jurel, S.Shymanska, M.Golender, L.Gas-liquid chromatography of some aliphatic and heterocyclic mono- and pollyfunctional amines. VII. Retention indices of amines in some polar and unpolar stationary phasesLatv. PSR Zinat. Akad. Vestis Kim. Ser.1973, 1, 51-63.
Kovats' RI, polar column, isothermal
expand collapse
Column Shape
Packed
Active Phase(℃)
PEG-2000
Retention index
1889.
Temperature Control
200.
Method
isothermal
Comments
He, Celite 545 (44-60 mesh); Column length: 3. m
Reference
Anderson, A.Jurel, S.Shymanska, M.Golender, L.Gas-liquid chromatography of some aliphatic and heterocyclic mono- and pollyfunctional amines. VII. Retention indices of amines in some polar and unpolar stationary phasesLatv. PSR Zinat. Akad. Vestis Kim. Ser.1973, 1, 51-63.
Kovats' RI, polar column, isothermal
expand collapse
Column Shape
Packed
Active Phase(℃)
PEG-2000
Retention index
1906.
Temperature Control
200.
Method
isothermal
Comments
He, Celite 545 (44-60 mesh); Column length: 3. m
Reference
Anderson, A.Jurel, S.Shymanska, M.Golender, L.Gas-liquid chromatography of some aliphatic and heterocyclic mono- and pollyfunctional amines. VII. Retention indices of amines in some polar and unpolar stationary phasesLatv. PSR Zinat. Akad. Vestis Kim. Ser.1973, 1, 51-63.

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