quinoline

CAS No. 91-22-5

Formula: C9H7N
Basic Info

Quinoline is a heterocyclic aromatic organic compound with the chemical formula C9H7N. It is a colorless hygroscopic liquid with a strong odor. Aged samples, especially if exposed to light, become yellow and later brown. Quinoline is only slightly soluble in cold water but dissolves readily in hot water and most organic solvents. Quinoline itself has few applications, but many of its derivatives are useful in diverse applications. A prominent example is quinine, an alkaloid found in plants. 4-Hydroxy-2-alkylquinolines (HAQs) are involved in antibiotic resistance.

Formula
C9H7N
Molecular Weight
129.159
Exact Mass
129.058
LogP
2.2348
PSA
12.89
Synonyms

Benzopyridine

Leucol

Chinoleine

1-Azanaphthalene

1-Benzazine

Chinoline

Quinoline

Quinolin

Chinolin

expand collapse

Properties
Appearance & Physical State
colourless to brown liquid
Density
1.095
Boiling Point
237ºC
Melting Point
-15ºC
Flash Point
101ºC
Refractive Index
1.623-1.626
Water Solubility
slightly soluble
Stability
Stable. Incompatible with strong acids, strong oxidizing agents. May discolour on exposure to light. Hygroscopic - protect from moisture. Reacts violently and unpredictably with some materials, especially strong oxidizing agents.
Vapor Density
4.5 (vs air)
Vapor Pressure
0.07 mm Hg ( 20 °C)
Safety Info
RTECS
VA9275000
Safety Statements
S26-S36/37/39
WGK Germany
2
Risk Statements
R21/22; R37/38; R40; R41; R68
HS Code
2933499090
RIDADR
UN 2656
Hazard Class
6.1
Packing Group
III
Caution Statement
P201; P280; P305 + P351 + P338; P308 + P313
Hazard Codes
Spectrum
NMR Spectrum 1H NMR : 400 MHz in CDCl3
expand collapse
IR Spectrum IR : liquid film
expand collapse
Mass Spectrum Mass spectrum (electron ionization)
expand collapse
UV Spectrum UV/Visible spectrum
expand collapse
Toxicity
SKIN/EYE IRRITATION DATA
expand collapse
Type of Test
Standard Draize test
Exposure Route
Administration onto the skin
Species Observed
Rodent - rabbit
Dose/Duration
100 mg/24H
Toxic Effects
--
Reference
Prehled Prumyslove Toxikologie; Organicke Latky, Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,848,1986
ACUTE TOXICITY DATA
expand collapse
Type of Test
LD50 - Lethal dose, 50 percent kill
Exposure Route
Oral
Species Observed
Rodent - rat
Dose/Duration
331 mg/kg
Toxic Effects
Details of toxic effects not reported other than lethal dose value--
Reference
Prehled Prumyslove Toxikologie; Organicke Latky, Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,848,1986
ACUTE TOXICITY DATA
expand collapse
Type of Test
LD50 - Lethal dose, 50 percent kill
Exposure Route
Administration onto the skin
Species Observed
Rodent - rabbit
Dose/Duration
540 uL/kg
Toxic Effects
Details of toxic effects not reported other than lethal dose value--
Reference
AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,119,1951

Related Compound Information

PRODUCTS
Coming Soon
SUPPLIERS
Coming Soon
BRANDING
Coming Soon