Pyruvic acid

CAS No. 127-17-3

Formula: C3H4O3
Basic Info

Pyruvic acid (CH3COCOOH) is the simplest of the alpha-keto acids, with a carboxylic acid and a ketone functional group. Pyruvate, the conjugate base, CH3COCOO−, is a key intermediate in several metabolic pathways.
Pyruvic acid can be made from glucose through glycolysis, converted back to carbohydrates (such as glucose) via gluconeogenesis, or to fatty acids through a reaction with acetyl-CoA. It can also be used to construct the amino acid alanine and can be converted into ethanol or lactic acid via fermentation.
Pyruvic acid supplies energy to cells through the citric acid cycle (also known as the Krebs cycle) when oxygen is present (aerobic respiration), and alternatively ferments to produce lactate when oxygen is lacking (fermentation).

Formula
C3H4O3
Molecular Weight
88.0621
Exact Mass
88.016
LogP
-0.34
PSA
54.37
Synonyms

PYRUVIC ACID pure

2-ketopropanoic acid

Pyruvic Acid

2-oxo-propanoicaci

PYRUVIC-ACID

2-Oxopropanoic acid

pyruvic

ACETYLFORMIC ACID

2-oxopropionic acid

Propanoic acid, 2-oxo-

CH3COCOOH

ACID PYRUVATE

FEMA 2970

PYRORACEMIC ACID

2-Ketopropionic Acid

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Properties
Appearance & Physical State
Colorless to light yellow liquid
Density
1.25
Boiling Point
165ºC
Melting Point
11.8ºC
Flash Point
82ºC
Refractive Index
1.426-1.43
Stability
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases. Refrigerate.
Storage Condition
2-8ºC
Vapor Pressure
0.968mmHg at 25°C
Safety Info
RTECS
UZ0829800
Safety Statements
S25-S36/37/39-S45
WGK Germany
3
Risk Statements
R34
HS Code
29335995
RIDADR
UN 3265 8/PG 2
Hazard Class
8
Packing Group
II
Caution Statement
P280; P305 + P351 + P338; P310
Hazard Codes
Hazard Declaration
Spectrum
NMR Spectrum 1H NMR : parameter in CDCl3
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IR Spectrum IR : liquid film
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Mass Spectrum Mass
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Analysis Methods
Normal alkane RI, non-polar column, custom temperature program
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Column Shape
Other
Active Phase(℃)
Methyl Silicone
Retention index
1249.
Temperature Control
Method
custom temperature program
Comments
Program: not specified
Reference
Ardrey, R.E.Moffat, A.C.Gas-liquid chromatographic retention indices of 1318 substances of toxicological interest on SE-30 or OV-1 stationary phaseJ. Chromatogr.1981, 220, 3, 195-252.

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