2-Hexanone (methyl butyl ketone, MBK) is a ketone used as a general solvent and in paints. It dissolves cellulose nitrate, vinyl polymers and copolymers, and natural and synthetic resins. It is recommended as a solvent because it is photochemically inactive; however it has a very low safe threshold limit value (MAK value). 2-Hexanone is absorbed through the lungs, orally and dermally and its metabolite, 2,5-hexanedione, is neurotoxic. Animal tests have shown that the neurotoxic effect of 2-hexanone may be potentiated by simultaneous administration of 2-butanone (methyl ethyl ketone, MEK).
methyl n-butyl ketone
n-butyl methyl ketone
Appearance & Physical State
colorless to pale yellow liquid
2 g/100 mL (20 ºC)
Stable. Flammable. Incompatible with oxidizing agents, strong bases, reducing agents.
Sense Organs and Special Senses (Eye)--effect, not otherwise specified<br>Behavioral--headache<br>Gastrointestinal--nausea or vomiting
Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,78,1974