esomeprazole

CAS No. 119141-88-7

Formula: C17H19N3O3S
Basic Info

Esomeprazole sold under the brand name Nexium among others, is a proton pump inhibitor which reduces stomach acid. It is used in the treatment of dyspepsia, peptic ulcer disease, gastroesophageal reflux disease, and Zollinger-Ellison syndrome.
It decreases secretion of acid through inhibition of the H+/K+-ATPase in the parietal cells of the stomach. By inhibiting the functioning of this transporter, the drug prevents formation of stomach acid.
Esomeprazole is the (S)-(−)-enantiomer of omeprazole. Esomeprazole is currently sold over the counter in the US and the UK.

Formula
C17H19N3O3S
Molecular Weight
345.416
Exact Mass
345.115
LogP
3.7654
PSA
96.31
Synonyms

S-enantiomer of omeprazole

esomeprazolum

(-)-Omeprazole

Esomeprazole (INN)

(S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole

[14C]-(-)-Omeprazole

(S)-6-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole

Esomeprazole

(S)-(-)-omeprazole

esomeprazol

(S)-Esomeprazole

UNII-N3PA6559FT

6-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole

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Properties
Density
1.37g/cm3
Boiling Point
600ºC at 760mmHg
Flash Point
316.7ºC
Refractive Index
1.669
Vapor Pressure
0mmHg at 25°C
Safety Info
HS Code
2933990090
Spectrum
NMR Spectrum 1H NMR : Predict
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Related Compound Information

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