CAS No. 106-89-8

Formula: C3H5ClO
Basic Info

Epichlorohydrin (abbreviated ECH) is an organochlorine compound and an epoxide. Despite its name, it is not a halohydrin. It is a colorless liquid with a pungent, garlic-like odor, moderately soluble in water, but miscible with most polar organic solvents. It is a chiral molecule generally existing as a racemic mixture of right-handed and left-handed enantiomers. Epichlorohydrin is a highly reactive compound and is used in the production of glycerol, plastics, epoxy glues and resins, and elastomers. In contact with water, epichlorohydrin hydrolyzes to 3-MCPD, a carcinogen found in food.

Molecular Weight
Exact Mass



3-Chloropropylene Oxide












expand collapse

Appearance & Physical State
clear, colorless
Boiling Point
Melting Point
Flash Point
Refractive Index
Stability Unstable. Flammable - note wide explosion limits and low flash point. Vapours may flow along surfaces to source of ignition. Contact with strong oxidisers may lead to fire. Incompatible with strong acids, strong bases, strong oxidizing agents, me
Storage Condition
Refrigerator (+4ºC) + Flammables area
Vapor Pressure
22mmHg at 25°C
Safety Info
Safety Statements
WGK Germany
Risk Statements
R10; R23/24/25; R34; R43; R45
HS Code
UN 2023
Hazard Class
Packing Group
Hazard Codes
SDS 1.0
expand collapse
Download/Modify | Technical supported by XiXisys.com. For US version, EU version (23 languages) and more, please refer to xixisys.com/en/sds/search


According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017


1.1 GHS Product identifier

Product name epichlorohydrin

1.2 Other means of identification

Product number -
Other names (±)-Epichlorohydrin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. The primary use of epichlorohydrin is in the production of epoxy resins used in coatings, adhesives, and plastics. Epichlorohydrin is also used in the manufacture of synthetic glycerine, textiles, paper, inks and dyes, solvents, surfactants, and pharmaceuticals. Epichlorohydrin is also listed as an inert ingredient in commercial pesticides.
Uses advised against no data available

1.4 Supplier's details

Company MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road,
Xuhui District, Shanghai, China
Telephone +86(21)64956998
Fax +86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-400-6021-666
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Flammable liquids, Category 3

Acute toxicity - Oral, Category 3

Acute toxicity - Dermal, Category 3

Skin corrosion, Category 1B

Skin sensitization, Category 1

Acute toxicity - Inhalation, Category 3

Carcinogenicity, Category 1B

2.2 GHS label elements, including precautionary statements

Signal word


Hazard statement(s)

H226 Flammable liquid and vapour

H301 Toxic if swallowed

H311 Toxic in contact with skin

H314 Causes severe skin burns and eye damage

H317 May cause an allergic skin reaction

H331 Toxic if inhaled

H350 May cause cancer

Precautionary statement(s)

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.

P233 Keep container tightly closed.

P240 Ground and bond container and receiving equipment.

P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.

P242 Use non-sparking tools.

P243 Take action to prevent static discharges.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P272 Contaminated work clothing should not be allowed out of the workplace.

P271 Use only outdoors or in a well-ventilated area.

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and understood.


P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower].

P370+P378 In case of fire: Use ... to extinguish.

P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/…

P321 Specific treatment (see ... on this label).

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P312 Call a POISON CENTER/doctor/…if you feel unwell.

P361+P364 Take off immediately all contaminated clothing and wash it before reuse.

P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P363 Wash contaminated clothing before reuse.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P310 Immediately call a POISON CENTER/doctor/…

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P333+P313 If skin irritation or rash occurs: Get medical advice/attention.

P362+P364 Take off contaminated clothing and wash it before reuse.

P311 Call a POISON CENTER/doctor/…

P308+P313 IF exposed or concerned: Get medical advice/ attention.


P403+P235 Store in a well-ventilated place. Keep cool.

P405 Store locked up.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.


P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification


3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
epichlorohydrin epichlorohydrin 106-89-8 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention.

In case of skin contact

Wear protective gloves when administering first aid. First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Put clothes in sealable container. Refer immediately for medical attention.

In case of eye contact

Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.

If swallowed

Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention.

4.2 Most important symptoms/effects, acute and delayed

This compound is caustic as both a liquid and gas. Irritation of the eyes and skin, and skin sensitization has been observed. Exposure to epichlorohydrin has caused inflammation of the lungs, asthmatic bronchitis, and liver and kidney damage. In acute poisonings, death may be caused by respiratory paralysis. (EPA, 1998)

4.3 Indication of immediate medical attention and special treatment needed, if necessary


5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Avoid use of dry chemical if fire occurs in container with confined vent. Containers may explode in fire because of polymerization.

5.2 Specific hazards arising from the chemical

When heated to decomposition, this compound evolves highly toxic fumes of phosgene and carbon monoxide. Reactive and incompatible with strong oxidizers, strong acids, caustics, zinc, aluminum, chlorides of iron and aluminumand compounds with an active hydrogen atom, including water. Unstable, avoid heat, contaminants, strong acids and bases, certain curing agents such as ethylenediamine. Hazardous polymerization may occur. (EPA, 1998)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Do NOT wash away into sewer. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

6.3 Methods and materials for containment and cleaning up

Remove all ignition sources. Ventilate area of spill or leak.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Fireproof. Separated from strong oxidants, acids, bases, aluminium, zinc, amines and food and feedstuffs. Well closed.Separate from acids, alkalies, salts, water, and oxidizers. Store in a cool, dry, well-ventilated location. Inside storage should be in a standard flammable liquids storage warehouse, room, or cabinet.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

NIOSH considers epichlorohydrin to be a potential occupational carcinogen.

NIOSH usually recommends that occupational exposures to carcinogens be limited to the lowest feasible concn.

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state clear, colorless
Colour Colorless liquid
Odour Odor is sweet, pungent or chloroform-like ... generally perceived as a slightly irritating chloroformlike odor
Melting point/ freezing point -26°C(lit.)
Boiling point or initial boiling point and boiling range 117°C
Flammability Class IC Flammable Liquid: Fl.P. at or above 22.78°C and below 37.78°C.Flammable. Gives off irritating or toxic fumes (or gases) in a fire.
Lower and upper explosion limit / flammability limit Lower flammable limit: 3.8% and upper flammable limit: 21.0%.
Flash point 32°C(lit.)
Auto-ignition temperature 411.11°C (USCG, 1999)
Decomposition temperature no data available
pH no data available
Kinematic viscosity 0.0103 poise at 25°C
Solubility 50 to 100 mg/mL at 22.22°C
Partition coefficient n-octanol/water (log value) log Kow = 0.45
Vapour pressure 22mmHg at 25°C
Density and/or relative density 1.183
Relative vapour density 3.29 (EPA, 1998) (Relative to Air)
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Epichlorohydrin can be oxidized by free radical process in liquid or gas phases; these reactions may occur as photochemically initiated atmospheric reactions.

10.3 Possibility of hazardous reactions

Flammable liquid when exposed to heat or flame.1-CHLORO-2,3-EPOXYPROPANE may polymerize exothermically if heated or contaminated. Reacts explosively with aniline. Ignites on contact with potassium tert-butoxide. Reacts with trichloroethylene to give the explosive dichloroacetylene. Violent reaction with sulfuric acid or isopropylamine. Exothermic polymerization on contact with strong acids or bases, zinc, aluminum, aluminum chloride, iron, ferric chloride [Sax, 9th ed., 1996, p. 1469].

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Strong oxidizers, strong acids, certain salts, caustics, zinc, aluminum, water [Note: May polymerize in presence of strong acids and bases particularly when hot.].

10.6 Hazardous decomposition products

When heated to decomp, emits toxic fumes of /hydrogen chloride/.

11.Toxicological information

Acute toxicity

  • Oral: LD50 Guinea pig oral 178 mg/kg
  • Inhalation: LC50 Rat inhalation 250 ppm/8 hr
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available


Cancer Classification: Group B2 Probable Human Carcinogen

Reproductive toxicity

In humans occupationally exposed to epichlorohydrin, effects on sperm counts, hormone levels, and fertility have been not detected. Epichlorohydrin has been demonstrated to reduce fertility in male rats when inhaled or administered orally. (-) Teratogenic effects (birth defects) have not been observed in studies of rodents exposed by inhalation or ingestion.

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: LC50; Species: Danio rerio (Zebra danio); Conditions: static; Concentration: 30500 ug/L for 96 hr /formulation
  • Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (Water flea); Conditions: static, 20-22°C, pH 7.6-7.7, oxygen saturated; Concentration: 30 mg/L for 24 hr /from table
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: An unspecified amount of epichlorohydrin reached 18% of its theoretical BOD in 1 week using an activated sludge inoculum and the Japanese MITI test(1). Pure cultures were able to biodegrade epichlorohydrin rapidly to 3-chloro-1,2-propanediol(2). Epichlorohydrin achieved 3% of the theoretical BOD in a sewage sludge over a 5 day incubation period, but achieved 14% of the theoretical BOD following acclimation(3). Epichlorohydrin was 67% biodegraded in an activated sludge degradability test following a 1 day acclimation period(4).

12.3 Bioaccumulative potential

An estimated BCF of 3 was calculated for epichlorohydrin(SRC), using a log Kow of 0.45(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low.

12.4 Mobility in soil

The Koc of epichlorohydrin is estimated as 40(SRC), using a log Kow of 0.45(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that epichlorohydrin is expected to have very high mobility in soil(SRC).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods


The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN2023 IMDG: UN2023 IATA: UN2023

14.2 UN Proper Shipping Name


14.3 Transport hazard class(es)

ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1

14.4 Packing group, if applicable


14.5 Environmental hazards

ADR/RID: no IMDG: no IATA: no

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
epichlorohydrin epichlorohydrin 106-89-8 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 10, 2017
Revision Date Aug 10, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%


  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
expand collapse
  Epichlorohydrin      Revision number: 5    

  Product name:        Epichlorohydrin    
  Revision number:        5    

  GHS classification
    Category 3
  Flammable liquids
    Category 3
  Acute toxicity (Oral)
  Acute toxicity (Dermal)        Category 3    
    Category 2
  Acute toxicity (Inhalation)
  Skin corrosion/irritation        Category 1B    
    Category 1
  Serious eye damage/eye irritation
  Respiratory sensitization        Category 1    
    Category 1
  Skin sensitization
  Germ cell mutagenicity        Category 2    
    Category 1B
  Reproductive toxicity        Category 2    
  Specific target organ toxicity        Liver, Respiratory system, Kidney, Central nervous system    
  - Single exposure [Category 1]
  Specific target organ toxicity        Liver, Respiratory system, Heart, Kidney, Central nervous    
  - Repeated exposure [Category 1]        system, Lung    
  Acute aquatic hazard        Category 3    
  GHS label elements, including precautionary statements
  Pictograms or hazard symbols
  Signal word
  Hazard statements        Flammable liquid and vapour    
    Toxic if swallowed or in contact with skin
    Fatal if inhaled
    Causes severe skin burns and eye damage
    May cause allergy or asthma symptoms or breathing
    difficulties if inhaled
    May cause an allergic skin reaction
    Suspected of causing genetic defects
    May cause cancer
    Suspected of damaging fertility or the unborn child

    Causes damage to organs : Liver Respiratory system Kidney
    Central nervous system
    Causes damage to organs through prolonged or repeated
    exposure : Liver Respiratory system Heart Kidney Central
    nervous system Lung
    Harmful to aquatic life
  Precautionary statements:
  [Prevention]        Obtain special instructions before use.    
    Do not handle until all safety precautions have been read and understood.
    Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
    Keep container tightly closed.
    Use explosion-proof electrical/ventilating/lighting equipment. Take precautionary
    measures against ignition by the static discharge and the spark.
    Do not breathe dust/fume/gas/mist/vapours/spray.
    Use only outdoors or in a well-ventilated area.
    Avoid release to the environment.
    Do not eat, drink or smoke when using this product.
    Contaminated work clothing should not be allowed out of the workplace.
    Wash hands thoroughly after handling.
    Wear respiratory protection.
    Wear protective gloves and eye/face protection.
  [Response]        IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for    
    breathing. Immediately call a POISON CENTER or doctor/physician.
    IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Rinse
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
    if present and easy to do. Continue rinsing.
    IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse
    skin with water/shower.
    If skin irritation or rash occurs: Get medical advice/attention.
    Remove/Take off immediately all contaminated clothing.
    Wash contaminated clothing before reuse.
    Immediately call a POISON CENTER or doctor/physician.
  [Storage]        Store in a well-ventilated place. Keep container tightly closed.    
    Store locked up.
  [Disposal]        Dispose of contents/container through a waste management company authorized by    
    the local government.
  Other hazards which do not        May cause polimerization.    
  result in classification

  Components:        Epichlorohydrin    
  Percent:        >99.0%(GC)    
  CAS Number:        106-89-8    
  Synonyms:        Chloromethyloxirane , 3-Chloropropylene Oxide , 1-Chloro-2,3-epoxypropane    
  Chemical Formula:        C3H5ClO    

  Inhalation:        Remove victim to fresh air and keep at rest in a position comfortable for breathing.    
    Immediately call a POISON CENTER or doctor/physician.
  Skin contact:        Remove/Take off immediately all contaminated clothing. Gently wash with plenty of    
    soap and water. Immediately call a POISON CENTER or doctor/physician.
  Eye contact:        Rinse cautiously with water for several minutes. Remove contact lenses, if present    
    and easy to do. Continue rinsing.Immediately call a POISON CENTER or
  Ingestion:        Immediately call a POISON CENTER or doctor/physician. Rinse mouth.    
  Most important        Burning sensation, Cough, Sore throat, Headache, Laboured breathing, Nausea,    
  symptoms/effects, acute Shortness of breath, Vomiting, Tremor, Gastrospasm, Diarrhoea, Collapse, Redness,
  and delayed:        Burn, Pain, Blistering, Blurred Vvsion    
  Protection of first-aiders: A rescuer should wear personal protective equipment, such as rubber gloves and air-
    tight goggles.
  Indication of immediate Medical ovservation is indicated. Depending on the degree of exposure, periodic
  medical attantion and        medical examination is indicated.    
  special treatment needed, if

    Dry chemical, foam, water spray, carbon dioxide.
  Suitable extinguishing
  Unsuitable extinguishing Solid streams of water
  Specific hazards arising This substance may polimerize explosively when heated or involved in a fire.
  from the chemical:        Container may explode when heated. Combat fire from a sheltered position.    
    Take care as it may decompose upon combustion or in high temperatures to
    generate poisonous fume.
  Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing
    method according to the surrounding situation is used. Uninvolved persons should
    evacuate to a safe place. In case of fire in the surroundings: Keep containers cool by
    spraying with water. Eliminate all ignition sources if safe to do so.
  Special protective        When extinguishing fire, be sure to wear personal protective equipment.    
  equipment for firefighters:

  Personal precautions,        Use extra personal protective equipment (self-contained breathing apparatus). Keep    
  protective equipment and people away from and upwind of spill/leak. Ensure adequate ventilation. Entry to non-
  emergency procedures: involved personnel should be controlled around the leakage area by roping off, etc.
  Environmental precautions: Prevent product from entering drains.
  Methods and materials for Absorb spilled material in dry sand or inert absorbent before recovering it into a
  containment and cleaning covered container. In case of large amount of spillage, contain a spill by bunding.
  up: Adhered or collected material should be promptly disposed of, in accordance with
    appropriate laws and regulations.
  Prevention of secondary Remove all sources of ignition. Fire-extinguishing devices should be prepared in
  hazards:        case of a fire. Use spark-proof tools and explosion-proof equipment.    

  Precautions for safe handling
  Technical measures:        Handling is performed in a well ventilated place. Wear suitable protective equipment.    
    Prevent generation of vapour or mist. Keep away from heat/sparks/open flame/hot
    surfaces. -No smoking. Take measures to prevent the build up of electrostatic
    charge. Use explosion-proof equipment. Wash hands and face thoroughly after
    Use a closed system if possible. Use a ventilation, local exhaust if vapour or aerosol
    will be generated.
  Advice on safe handling: Avoid all contact!
  Conditions for safe storage, including any
  Storage conditions:        Keep container tightly closed. Store in a cool, dark and well-ventilated place.    
    Store locked up.
    Store away from incompatible materials such as oxidizing agents.
    Comply with laws.
  Packaging material:

  Engineering controls:        Install a closed system or local exhaust. Also install safety shower and eye bath.    

  Exposure limits:
  ACGIH TLV(TWA):        0.5 ppm (skin)    
  OSHA PEL(TWA):        5 ppm (skin)    
  Personal protective equipment
  Respiratory protection: Half or full facepiece respirator, self-contained breathing apparatus(SCBA), supplied
    air respirator, etc. Use respirators approved under appropriate government standards
    and follow local and national regulations.
    Impervious gloves.
  Hand protection:
  Eye protection:        Safety goggles. A face-shield, if the situation requires.    
  Skin and body protection: Impervious protective clothing. Protective boots, if the situation requires.

  Physical state (20°C):        Liquid    
  Form:        Clear    
  Odour:        Chloroform-like    
  Odour threshold:        0.93 ppm    
  pH: No data available
  Melting point/freezing point:-26°C
  Boiling point/range:        117°C    
  Flash point:        32°C    
  Flammability or explosive
  Lower:        3.8%    
  Upper:        21%    
  Vapour pressure:        1.6kPa/20°C    
  Vapour density:        3.2    
  Relative density:        1.18    
  [Water]        Soluble (6g/100mL)    
  [Other solvents]
  Miscible:        Many organic solvents    
  Log Pow:        0.26    
  Autoignition temperature:        385°C    

  Chemical stability:        Polymerization may occur under the influences of heat, light or on contact with    
    polymelization initiators such as peroxides etc.
  Possibility of hazardous No special reactivity has been reported.
  Conditions to avoid:        Heat, Spark, Open flame, Static discharge, Light    
  Incompatible materials: Oxidizing agents, Acids, Bases, Halogenated compounds, Magnesium, Their alloys,
    Metal powders, Sodium
  Hazardous decomposition Carbon monoxide, Carbon dioxide, Hydrogen chloride

  Acute Toxicity:        ihl-hmn TCLo:40 ppm/2H    
    ihl-rat LC50:250 ppm/8H
    orl-rat LD50:90 mg/kg
    skn-rbt LD50:515 mg/kg
  Skin corrosion/irritation: skn-rbt 10 mg/24H open
    eye-rbt 100 mg/24H MOD
  Serious eye
  damage/irritation:        eye-rbt 100 mg SEV    

  Germ cell mutagenicity: dni-hmn-hla 2700 umol/L
    mmo-esc 1 uL/plate (+/-S9)
    mmo-ssp 21 mmol/L (-S9)
    mmo-ssp 800 umol/L (+S9)
  Carcinogenicity:        ihl-rat TCLo:100 ppm/6H/30D-C    
    ipr-mus TDLo:2400 mg/kg/8W-I
    orl-rat TDLo:60 g/kg/81W-I
    scu-mus TDLo:720 mg/kg/18W-I
  IARC =        Group 2A (Probably carcinogenic to humans)    
  NTP =        b (Reasonably anticipated to be carcinogens)    
  Reproductive toxicity:        No data available    
  RTECS Number:        TX4900000    

  Fish:        No data available    
    No data available
  Algae:        No data available    
  Persistence / degradability: 68% (by BOD), 84% (by TOC), 93% (by GC)
  Bioaccumulative        3    
  Mobility in soil
  Log Pow:
  Soil adsorption (Koc):        40    
  Henry's Law

    Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material
    with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system.
    Observe all federal, state and local regulations when disposing of the substance.

    6.1: Toxic substance.
  Hazards Class:
  Subsidiary risk:        3: Flammable liquid.    
  Proper shipping name:        Epichlorohydrin    
  Packing group:
  Marine pollutant        Y    

  Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002
  and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport,
    loading and unloading were prescribed.
  The list of a dangerous chemical(2002)/CN-No.: 61052

NMR Spectrum 1H NMR : 90 MHz in CDCl3
expand collapse
IR Spectrum IR : CCl4 solution
expand collapse
Mass Spectrum Mass
expand collapse
Raman Spectrum Raman : 4880 A,200 M,liquid
expand collapse
Analysis Methods
Kovats' RI, non-polar column, isothermal
expand collapse
Column Shape
Active Phase(℃)
Retention index
Temperature Control
Gaschrom Q; Column length: 2. m
Winskowski, J.Gaschromatographische Identifizierung von Stoffen anhand von Indexziffem und unterschiedlichen DetektorenChromatographia1983, 17, 3, 160-165.
Kovats' RI, non-polar column, isothermal
expand collapse
Column Shape
Active Phase(℃)
Silicon High Vacuum Grease (obsolete)
Retention index
Temperature Control
H2, Celite
Janák, J.Jonas, J.Kratochvíl, M.Identification of some acetals of the tetrahydrofurane sereis by gas chromatography with the aid of the Kováts indicesCollect. Czech. Chem. Commun.1965, 30, 1, 265-276.
Normal alkane RI, non-polar column, temperature ramp
expand collapse
Column Shape
Active Phase(℃)
Retention index
Temperature Control
temperature ramp
25. m/0.20 mm/0.10 μm, N2/He, 6. K/min; T<sub>start</sub>: 50. C; T<sub>end</sub>: 250. C
Zenkevich, I.G.Experimentally measured retention indices.2005.
Normal alkane RI, non-polar column, temperature ramp
expand collapse
Column Shape
Active Phase(℃)
Retention index
Temperature Control
temperature ramp
36. m/0.25 mm/0.25 μm, 5. K/min; T<sub>start</sub>: 35. C; T<sub>end</sub>: 240. C
Huang, C.Liang, H.Han, S.The analysis of organic compounds in waste water by gas extraction/thermal desorption/gas chromatography-mass spectrometryChin. J. Chromatogr.1996, 14, 6, 421-424.
Normal alkane RI, non-polar column, custom temperature program
expand collapse
Column Shape
Active Phase(℃)
Retention index
Temperature Control
custom temperature program
60. m/0.53 mm/5. μm, He; Program: 40C(6min) =&gt; 5C/min =&gt; 80C =&gt; 10C/min =&gt; 200C
Flanagan, R.J.Streete, P.J.Ramsey, J.D.Volatile Substance AbuseUNODC Technical Series, No 5, United Nations, Office on Drugs and Crime, Vienna International Centre, PO Box 500, A-1400 Vienna, Austria, 1997, 56, retrieved from http://www.odccp.org/pdf/technica

Related Compound Information

Coming Soon
Coming Soon
Coming Soon